Adama University

About: Adama University is a education organization based out in Nazrēt, Ethiopia. It is known for research contribution in the topics: Population & Adsorption. The organization has 840 authors who have published 1010 publications receiving 5547 citations. The organization is also known as: Adama Science and Technology University & ቴክኖሎጂ ዩኒቨርሲቲ, አዳማ ሳይንስና ቴክኖሎጂ ዩኒቨርሲቲ.

Modeling Heat Transfer Enhancement of Ferrofluid (Fe3O4–H2O) Flow in a Microchannel Filled with a Porous Medium

Abstract: Heat transfer characteristics and hydrodynamical properties of ferrofluid through microchannels with non-uniform permeable walls temperature and filled with porous media plays an important role in modern microfluidic applications, such as solar collectors, nuclear reactors, micro-electro-chemical cell transport, micro heat exchanging, microchip cooling, and electronic equipment. Therefore, this paper presents the investigation of ferrofluid (Fe3O4-H2O) heat transfer characteristics as well as hydrodynamical properties in a permeable microchannel with non-uniform permeable walls. The semi-discretization finite difference method is utilized to solve the highly non-linear partial differential equations that govern the momentum and energy equations. Accordingly, the numerical outcomes reveal that the ferrofluid velocity and temperature profiles indicate a rising trend as the pressure gradient parameter, the variable viscosity parameter, the Darcy number, the Eckert number, and Prandtl number increase. The Reynolds number, which is a suction/injection parameter, shows a contrary influence on the ferrofluid velocity and temperature whereas nanoparticles volume fraction and the Forchheimer constant show a decreasing effect on the ferrofluid velocity and temperature. The outcomes also depict that the coefficient of skin friction at the cold wall of the microchannel is larger for higher values of the nanoparticles volume fraction, the variable viscosity parameter, the Darcy number, and the Eckert number. Besides, the coefficient of skin friction at the hot wall rises with the Darcy number, and the Prandtl number. Furthermore, the heat transfer rate at both cold and hot walls of the microchannel increases as the variable viscosity parameter, the Darcy number, the Eckert number, and the Prandtl number increase. The nanoparticles volume fraction and Darcy number show a retarding effect on the heat transfer rate at both walls of the microchannel.

Synthesis, Molecular Docking Analysis, and Evaluation of Antibacterial and Antioxidant Properties of Stilbenes and Pinacol of Quinolines.

Abstract: Emergence of antimicrobial resistance to standard commercial drugs has become a critical public health concern worldwide. Hence, novel antimicrobials with improved biological activities are urgently needed. In this regard, a series of quinoline-stilbene derivatives were synthesized from substituted quinoline and benzyltriphenylphosphonium chloride using Wittig reaction. Furthermore, a novel pinacol of quinoline was synthesized by pinacolinazation of 2-methoxyquinoline-3-carbaldehyde which was achieved by aluminum powder-potassium hydroxide reagent combination at ambient temperature in methanol. The structures of the synthesized compounds were established based on their spectral data. The antibacterial activities of the synthesized compounds were evaluated in vitro by the paper disc diffusion method against two Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) and two Gram-negative bacteria (Escherichia coli and Salmonella typhimurium). The best activity was displayed by compound 19 against E. coli with an inhibition zone of 16.0 ± 0.82 mm and 14.67 ± 0.94 mm at 500 and 250 μg/mL, respectively. This is close to ciprofloxacin which is used as a positive control. The results of in silico molecular docking evaluation of the compounds against E. coli DNA gyraseB were in good agreement with the in vitro antibacterial analysis. Compounds 19 (−6.9 kcal/mol) and 24 (−7.1 kcal/mol) showed the maximum binding affinity close to ciprofloxacin (−7.3 kcal/mol) used as positive control. Therefore, the antibacterial activity displayed by these compounds is encouraging for further investigation to improve the activities of quinoline-stilbenes by incorporating various bioisosteric groups in one or more positions of the phenyl nuclei for their potential pharmacological use. Findings of the DPPH radical scavenging assay indicated that some of the quinolone stilbenes and pinacol possess moderate antioxidant properties compared to ascorbic acid used as a natural antioxidant.

Coupled fixed points theorems for generalized weak contractions in ordered b-metric spaces

Abstract: In this paper, we prove some fixed points, coupled coincidence point and coupled common fixed point results for mappings satisfying an almost generalized contraction conditions in partially ordered...