Institution
Brown University
Education•Providence, Rhode Island, United States•
About: Brown University is a education organization based out in Providence, Rhode Island, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 35778 authors who have published 90896 publications receiving 4471489 citations. The organization is also known as: brown.edu & Brown.
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TL;DR: It is found that in the National Weight Control Registry, successful long-term weight loss maintainers share common behavioral strategies, including eating a diet low in fat, frequent self-monitoring of body weight and food intake, and high levels of regular physical activity.
Abstract: ▪ Abstract Obesity is now recognized as a serious chronic disease, but there is pessimism about how successful treatment can be. A general perception is that almost no one succeeds in long-term maintenance of weight loss. To define long-term weight loss success, we need an accepted definition. We propose defining successful long-term weight loss maintenance as intentionally losing at least 10% of initial body weight and keeping it off for at least 1 year. According to this definition, the picture is much more optimistic, with perhaps greater than 20% of overweight/obese persons able to achieve success. We found that in the National Weight Control Registry, successful long-term weight loss maintainers (average weight loss of 30 kg for an average of 5.5 years) share common behavioral strategies, including eating a diet low in fat, frequent self-monitoring of body weight and food intake, and high levels of regular physical activity. Weight loss maintenance may get easier over time. Once these successful main...
1,415 citations
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11 Sep 2000TL;DR: In this paper, the authors propose a methodology of the teleological power of judgment, which is a dialectic of the Aesthetic Power of Judgment (APJ) and the Teleological Power of judgment (TOPJ).
Abstract: Editor's introduction Part I. The First Draft of the Introduction: 1. The first draft of the introduction Part II. Critique of the Power of Judgment: 2. Preface 3. Introduction Part III. First Part: Critique of the Aesthetic Power of Judgment: 4. First section, first book: analytic of the beautiful 5. First section, second book: analytic of the sublime 6. Deduction of pure aesthetic judgments 7. Second section: the dialectic of the aesthetic power of judgment 8. Appendix: on the methodology of taste Part IV. Second Part: Critique of the Teleological Power of Judgment: 9. First division: analytic of the teleological power of judgment 10. Second division: dialectic of the teleological power of judgment 11. Appendix: methodology of the teleological power of judgment.
1,415 citations
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TL;DR: In this article, a necessary criterion for brittle fracture in crystals is established, in terms of the spontaneous emission of dislocations from an atomically sharp cleavage crack, and the stability of a sharp crack against emission of a blunting dislocation for a number of crystals and crystal types in two dimensions and the energy to form a stable loop of dislocation from the crack tip in three dimensions.
Abstract: A necessary criterion for brittle fracture in crystals is established, in terms of the spontaneous emission of dislocations from an atomically sharp cleavage crack. We have calculated the stability of a sharp crack against emission of a blunting dislocation for a number of crystals and crystal types in two dimensions and the energy to form a stable loop of dislocation from the crack tip in three dimensions. We find that contrary to previous expectations, an atomically sharp cleavage crack is stable in a wide range of crystal types, but that in the face centred cubic metals investigated, blunting reactions occur spontaneously. Of the body centred metals investigated, iron is an intermediate case between the brittle and ductile cases, and the ionic and covalent crystals investigated are all stable against dislocation emission. Qualitatively, we find that crystals whose dislocations have wide cores, and small values of the parameter μb/γ (μb/γ⋦7·5 to 10) are ductile while crystals with narrow cores ...
1,413 citations
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TL;DR: The treatment gap for mental disorders is universally large, though it varies across regions, and it is likely that the gap reported here is an underestimate due to the unavailability of community-based data from developing countries where services are scarcer.
Abstract: Mental disorders are highly prevalent and cause considerable suffering and disease burden. To compound this public health problem, many individuals with psychiatric disorders remain untreated although effective treatments exist. We examine the extent of this treatment gap. We reviewed community-based psychiatric epidemiology studies that used standardized diagnostic instruments and included data on the percentage of individuals receiving care for schizophrenia and other non-affective psychotic disorders, major depression, dysthymia, bipolar disorder, generalized anxiety disorder (GAD), panic disorder, obsessive-compulsive disorder (OCD), and alcohol abuse or dependence. The median rates of untreated cases of these disorders were calculated across the studies. Examples of the estimation of the treatment gap for WHO regions are also presented. Thirty-seven studies had information on service utilization. The median treatment gap for schizophrenia, including other non-affective psychosis, was 32.2%. For other disorders the gap was: depression, 56.3%; dysthymia, 56.0%; bipolar disorder, 50.2%; panic disorder, 55.9%; GAD, 57.5%; and OCD, 57.3%. Alcohol abuse and dependence had the widest treatment gap at 78.1%. The treatment gap for mental disorders is universally large, though it varies across regions. It is likely that the gap reported here is an underestimate due to the unavailability of community-based data from developing countries where services are scarcer. To address this major public health challenge, WHO has adopted in 2002 a global action programme that has been endorsed by the Member States.
1,412 citations
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TL;DR: In this paper, the authors present a new algorithm to model the input uncertainty and its propagation in incompressible flow simulations, which is represented spectrally by employing orthogonal polynomial functionals from the Askey scheme as trial basis to represent the random space.
1,412 citations
Authors
Showing all 36143 results
Name | H-index | Papers | Citations |
---|---|---|---|
Walter C. Willett | 334 | 2399 | 413322 |
Robert Langer | 281 | 2324 | 326306 |
Robert M. Califf | 196 | 1561 | 167961 |
Eric J. Topol | 193 | 1373 | 151025 |
Joan Massagué | 189 | 408 | 149951 |
Joseph Biederman | 179 | 1012 | 117440 |
Gonçalo R. Abecasis | 179 | 595 | 230323 |
James F. Sallis | 169 | 825 | 144836 |
Steven N. Blair | 165 | 879 | 132929 |
Charles M. Lieber | 165 | 521 | 132811 |
J. S. Lange | 160 | 2083 | 145919 |
Christopher J. O'Donnell | 159 | 869 | 126278 |
Charles M. Perou | 156 | 573 | 202951 |
David J. Mooney | 156 | 695 | 94172 |
Richard J. Davidson | 156 | 602 | 91414 |