Rockefeller University

About: Rockefeller University is a education organization based out in New York, New York, United States. It is known for research contribution in the topics: Population & Gene. The organization has 15867 authors who have published 32938 publications receiving 2940261 citations. The organization is also known as: Rockefeller University & Rockefeller Institute.

Stressed or stressed out: what is the difference?

Abstract: The term “allostasis” has been coined to clarify ambiguities associated with the word “stress.” Allostasis refers to the adaptive processes that maintain homeostasis through the production of mediators such as adrenalin, cortisol and other chemical messengers. These mediators of the stress response promote adaptation in the aftermath of acute stress, but they also contribute to allostatic overload, the wear and tear on the body and brain that result from being “stressed out.” This conceptual framework has created a need to know how to improve the efficiency of the adaptive response to stressors while minimizing overactivity of the same systems, since such overactivity results in many of the common diseases of modern life. This framework has also helped to demystify the biology of stress by emphasizing the protective as well as the damaging effects of the body's attempts to cope with the challenges known as stressors.

Nutritional studies with chlamydomonas reinhardi

Abstract: At present, we are investigating the genetic mechanisms involved in chlorophyll biosynthesis and chloroplast development. For this project, i t has been necessary to use a unicellular organism which is photosynthetic but can also be grown in the dark, and which has a sexual phase in its life-cycle. The ability of the organism to grow in the dark has been of particular importance because of our interest in mutants unable to synthesize chlorophyll and which are therefore non-photosynthetic. The sexual requirement is necessary for carrying out the genetic analysis. The organism chosen, Chlamydomonas reinhardi, a unicellular green alga, was isolated by Professor G. M. Smith, to whom we are indebted for the mating type strains used in this work. The nutritional studies to be reported here are concerned, first, with vegetative growth of the organism in light and dark and, second, with the nutritional conditions which we have found to be of critical importance in controlling the sexual phases of the life-cycle.