Université de Sherbrooke

About: Université de Sherbrooke is a education organization based out in Sherbrooke, Quebec, Canada. It is known for research contribution in the topics: Population & Receptor. The organization has 14922 authors who have published 28783 publications receiving 792511 citations. The organization is also known as: Universite de Sherbrooke & Sherbrooke University.

Coupling superconducting qubits via a cavity bus.

Abstract: Microfabricated superconducting circuit elements can harness the power of quantum behaviour for information processing. Unlike classical information bits, quantum information bits (qubits) can form superpositions or mixture states of ON and OFF, offering a faster, natural form of parallel processing. Previously, direct qubit–qubit coupling has been achieved for up to four qubits, but now two independent groups demonstrate the next crucial step: communication and exchange of quantum information between two superconducting qubits via a quantum bus, in the form of a resonant cavity formed by a superconducting transmission line a few millimetres long. Using this microwave cavity it is possible to store, transfer and exchange quantum information between two quantum bits. It can also perform multiplexed qubit readout. This basic architecture lends itself to expansion, offering the possibility for the coherent interaction of many superconducting qubits. The cover illustrates a zig-zag-shaped resonant cavity or quantum bus linking two superconducting phase qubits. One of two papers that demonstrate the communication of individual quantum states between superconducting qubits via a quantum bus. This quantum bus is a resonant cavity formed by a superconducting transmission line of several millimetres. Quantum information, initially defined in one qubit on one end, can be stored in this quantum bus and at a later time retrieved by a second qubit at the other end. Superconducting circuits are promising candidates for constructing quantum bits (qubits) in a quantum computer; single-qubit operations are now routine1,2, and several examples3,4,5,6,7,8,9 of two-qubit interactions and gates have been demonstrated. These experiments show that two nearby qubits can be readily coupled with local interactions. Performing gate operations between an arbitrary pair of distant qubits is highly desirable for any quantum computer architecture, but has not yet been demonstrated. An efficient way to achieve this goal is to couple the qubits to a ‘quantum bus’, which distributes quantum information among the qubits. Here we show the implementation of such a quantum bus, using microwave photons confined in a transmission line cavity, to couple two superconducting qubits on opposite sides of a chip. The interaction is mediated by the exchange of virtual rather than real photons, avoiding cavity-induced loss. Using fast control of the qubits to switch the coupling effectively on and off, we demonstrate coherent transfer of quantum states between the qubits. The cavity is also used to perform multiplexed control and measurement of the qubit states. This approach can be expanded to more than two qubits, and is an attractive architecture for quantum information processing on a chip.

The Mixed Methods Appraisal Tool (MMAT) Version 2018 for Information Professionals and Researchers.

Abstract: INTRODUCTION: Appraising the quality of studies included in systematic reviews combining qualitative and quantitative evidence is challenging. To address this challenge, a critical appraisal tool was developed: the Mixed Methods Appraisal Tool (MMAT). The aim of this paper is to present the enhancements made to the MMAT. DEVELOPMENT: The MMAT was initially developed in 2006 based on a literature review on systematic reviews combining qualitative and quantitative evidence. It was subject to pilot and interrater reliability testing. A revised version of the MMAT was developed in 2018 based on the results from usefulness testing, a literature review on critical appraisal tools and a modified e-Delphi study with methodological experts to identify core criteria. TOOL DESCRIPTION: The MMAT assesses the quality of qualitative, quantitative, and mixed methods studies. It focuses on methodological criteria and includes five core quality criteria for each of the following five categories of study designs: (a) qualitative, (b) randomized controlled, (c) nonrandomized, (d) quantitative descriptive, and (e) mixed methods. CONCLUSION: The MMAT is a unique tool that can be used to appraise the quality of different study designs. Also, by limiting to core criteria, the MMAT can provide a more efficient appraisal.

Fractionation of lignocellulosics by steam-aqueous pretreatments

Abstract: Physical processing or pretreatment of lignocellulosics concerns the ultrastructural modification of materials such as wood, straw and bagasse. The substrates produced can be subsequently converted by chemicals. The various pretreatment options will be discussed in the light of the ultrastructural, polymeric and chemical modifications that are obtained. The processes can be classified as follows: (i) steam; (ii) aqueous; and (iii) organosolvolysis treatments. All of these have their antecedents in the thermomechanical processes developed by the pulp and paper or fibreboard industries. Sequential application of thermomechanical technology leads to fractionation of the substrate into the major polymeric fractions: cellulose, hemicellulose and lignin in varying degrees of modification. A number of pretreatment concepts are now at a commercial scale and are being applied to produce foodstuffs from lignocellulosics for use by ruminant animals. The same techniques are being piloted in the energy and chemicals from lignocellulosics field.

Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity

Abstract: Background: Recent reports suggest that Clostridium difficile colitis may be evolving into a more severe disease. During the second half of 2002 we noted an increase in the number of patients with severe C. difficile -associated diarrhea (CDAD) in our institution. We describe cases of CDAD at our institution over a 13-year period and investigate changes in illness severity. Methods: We undertook a retrospective chart review of all cases of CDAD diagnosed at the Centre hospitalier universitaire de Sherbrooke from Jan. 1, 1991, to Dec. 31, 2003. Because the hospital serves a well-defined population of Quebec, we were also able to calculate population-based incidence during this period. We abstracted data on individual patients from patient charts and from hospital and pharmacy computer databases. We defined cases of CDAD as having a positive C. difficile cytotoxicity assay result, or endoscopic or histopathological evidence of pseudomembranous colitis. A case was considered complicated if one or more of the following was observed: megacolon, perforation, colectomy, shock requiring vasopressor therapy, or death within 30 days after diagnosis. Results: A total of 1721 cases of CDAD were diagnosed during the study period. The incidence increased from 35.6 per 100 000 population in 1991 to 156.3 per 100 000 in 2003; among patients aged 65 years or more, it increased from 102.0 to 866.5 per 100 000. The proportion of cases that were complicated increased from 7.1% (12/169) in 1991–1992 to 18.2% (71/390) in 2003 ( p p 9 /L or greater) and an elevated creatinine level (200 μmol/L or greater) were strongly associated with adverse outcomes: in 2003, 45 (40.9%) of 110 patients with a high leukocyte count or creatinine level, or both, had complicated CDAD and 28 (25.5%) died within 30 days after diagnosis. After adjustment for age and other confounding factors, patients initially given oral vancomycin therapy had a risk of progression to complicated CDAD that was 79% lower than the risk among patients initially treated with metronidazole (adjusted odds ratio 0.2, 95% confidence interval 0.06–0.8, p = 0.02). Interpretation: An epidemic of CDAD with an increased case-fatality rate has had important consequences on the elderly population of our region. Our observational data suggest that the equivalence of vancomycin and metronidazole in the treatment of CDAD needs to be questioned.

A review of vegetation indices

Abstract: In the field of remote sensing applications, scientists have developed vegetation indices (VI) for qualitatively and quantitatively evaluating vegetative covers using spectral measurements. The spectral response of vegetated areas presents a complex mixture of vegetation, soil brightness, environmental effects, shadow, soil color and moisture. Moreover, the VI is affected by spatial‐temporal variations of the atmosphere. Over forty vegetation indices have been developed during the last two decades in order to enhance vegetation response and minimize the effects of the factors described above. This paper summarizes, refers and discusses most of the vegetation indices found in the literature. It presents different existing classifications of indices and proposes to group them in a new classification.