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Institution

Université de Sherbrooke

EducationSherbrooke, Quebec, Canada
About: Université de Sherbrooke is a education organization based out in Sherbrooke, Quebec, Canada. It is known for research contribution in the topics: Population & Receptor. The organization has 14922 authors who have published 28783 publications receiving 792511 citations. The organization is also known as: Universite de Sherbrooke & Sherbrooke University.


Papers
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Journal ArticleDOI
TL;DR: ICU survivors of greater than or equal to 1 week of MV may be stratified into four disability groups based on age and ICU length of stay to stratify patients for post-ICU disability and recovery to 1 year after critical illness.
Abstract: Rationale: Disability risk groups and 1-year outcome after greater than or equal to 7 days of mechanical ventilation (MV) in medical/surgical intensive care unit (ICU) patients are unknown and may inform education, prognostication, rehabilitation, and study design.Objectives: To stratify patients for post-ICU disability and recovery to 1 year after critical illness.Methods: We evaluated a multicenter cohort of 391 medical/surgical ICU patients who received greater than or equal to 1 week of MV at 7 days and 3, 6, and 12 months after ICU discharge. Disability risk groups were identified using recursive partitioning modeling.Measurements and Main Results: The 7-day post-ICU Functional Independence Measure (FIM) determined the recovery trajectory to 1-year after ICU discharge and was an independent risk factor for 1-year mortality. The 7-day post-ICU FIM was predicted by age and ICU length of stay. By 2 weeks of MV, ICU patients could be stratified into four disability groups characterized by increasing risk...

233 citations

Journal ArticleDOI
TL;DR: This description of primary care attributes in measurable terms provides an evaluation lexicon to assess initiatives to renew primary health care and serves as a guide for instrument selection.
Abstract: PURPOSE In 2004, we undertook a consultation with Canadian primary health care experts to define the attributes that should be evaluated in predominant and proposed models of primary health care in the Canadian context. METHOD Twenty persons considered to be experts in primary health care or recommended by at least 2 peers responded to an electronic Delphi process. The expert group was balanced between clinicians (principally family physicians and nurses), academics, and decision makers from all regions in Canada. In 4 iterative rounds, participants were asked to propose and modify operational definitions. Each round incorporated the feedback from the previous round until consensus was achieved on most attributes, with a final consensus process in a face-to-face meeting with some of the experts. RESULTS Operational definitions were developed and are proposed for 25 attributes; only 5 rate as specific to primary care. Consensus on some was achieved early (relational continuity, coordination-continuity, family-centeredness, advocacy, cultural sensitivity, clinical information management, and quality improvement process). The definitions of other attributes were refined over time to increase their precision and reduce overlap between concepts (accessibility, quality of care, interpersonal communication, community orientation, comprehensiveness, multidisciplinary team, responsiveness, integration). CONCLUSION This description of primary care attributes in measurable terms provides an evaluation lexicon to assess initiatives to renew primary health care and serves as a guide for instrument selection.

233 citations

Journal ArticleDOI
TL;DR: In this paper, a survey of the empirical literature regarding the use and management of Intellectual Property rights (IPRs) is presented, focusing on the US, Canada, EU, Japan and Australia and the protection of IP in specific industry groups.

232 citations

Journal ArticleDOI
TL;DR: A hypothesis is proposed in which direct and indirect effects of SLA on each of NAR and RGR are decomposed, and which leads to a trade-off between SLA and NAR as a function of daily irradiance.
Abstract: Summary 1 Three separate experiments were conducted, involving 27 herbaceous species and 14 woody species aged 15–30 days, in order to determine the relative importance of net assimilation rate (NAR), specific leaf area (SLA) and leaf weight ratio (LWR) in explaining interspecific variations in relative growth rate. 2 Daily quantum inputs were 31·12 mol m−2 day−1 in the first experiment and 33·17 mol m−2 day−1 in the second and third experiments. This is about twice the typical irradiance of most other experiments in this area, but only about 85% of the daily photon flux in nature. Plants were cultivated in hydroponic sand culture in a solution containing 5·8 mm nitrogen. 3 RGR was strongly and positively correlated with NAR in all three experiments. RGR was weakly and negatively correlated with SLA, while the correlation between RGR and LWR was weak and variable. 4 These results are compared to those already published in the literature: the commonly reported result that interspecific variation in RGR is determined primarily by SLA is partly due to the low irradiance used in most experiments, and the relative importance of SLA and NAR changes depending on irradiance. 5 A hypothesis is proposed in which direct and indirect effects of SLA on each of NAR and RGR are decomposed, and which leads to a trade-off between SLA and NAR as a function of daily irradiance.

232 citations

Journal ArticleDOI
TL;DR: A new algorithm for determining the number of clusters in a given data set and a new validity index for measuring the "goodness" of clustering are presented.

232 citations


Authors

Showing all 15051 results

NameH-indexPapersCitations
Masashi Yanagisawa13052483631
Joseph V. Bonventre12659661009
Jeffrey L. Benovic9926430041
Alessio Fasano9647834580
Graham Pawelec8957227373
Simon C. Robson8855229808
Paul B. Corkum8857637200
Mario Leclerc8837435961
Stephen M. Collins8632025646
Ed Harlow8619061008
William D. Fraser8582730155
Jean Cadet8337224000
Vincent Giguère8222727481
Robert Gurny8139628391
Jean-Michel Gaillard8141026780
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202384
2022189
20211,858
20201,805
20191,625
20181,543