University of Jordan

About: University of Jordan is a education organization based out in Amman, Jordan. It is known for research contribution in the topics: Population & Medicine. The organization has 7796 authors who have published 13764 publications receiving 213526 citations.

Analytical approximate solutions of systems of fractional algebraic–differential equations by homotopy analysis method

Abstract: In this paper, we develop a framework to obtain approximate solutions to systems of algebraic–differential equations of fractional order by employing the homotopy analysis method (HAM). The study highlights the efficiency of the method and its dependence on the auxiliary parameter ħ . Numerical examples are examined to highlight the significant features of the HAM method. The method shows improvements over existing analytical techniques

Formulation and in vitro evaluation of xanthan gum or carbopol 934-based mucoadhesive patches, loaded with nicotine.

Abstract: Bilayer nicotine mucoadhesive patches were prepared and evaluated to determine the feasibility of the formulation as a nicotine replacement product to aid in smoking cessation. Nicotine patches were prepared using xanthan gum or carbopol 934 as a mucoadhesive polymers and ethyl cellulose as a backing layer. The patches were evaluated for their thickness, weight and content uniformity, swelling behavior, drug–polymers interaction, adhesive properties, and drug release. The physicochemical interactions between nicotine and the polymers were investigated by Fourier transform infrared (FTIR) spectroscopy. Mucoadhesion was assessed using two-arm balance method, and the in vitro release was studied using the Franz cell. FTIR revealed that there was an acid base interaction between nicotine and carbopol as well as nicotine and xanthan. Interestingly, the mucoadhesion and in vitro release studies indicated that this interaction was strong between the drug and carbopol whereas it was weak between the drug and xanthan. Loading nicotine concentration to non-medicated patches showed a significant decrease in the mucoadhesion strength of carbopol patches and no significant effect on the mucoadhesion strength of xanthan patches. In vitro release studies of the xanthan patches showed a reasonable fast initial release profile followed by controlled drug release over a 10-h period.

Enhanced multi-verse optimizer for task scheduling in cloud computing environments

Abstract: Cloud computing is a trending technology that allows users to use computing resources remotely in a pay-per-use model. One of the main challenges in cloud computing environments is task scheduling, in which tasks should be scheduled efficiently to minimize execution time and cost while maximizing resources’ utilization. Many meta-heuristic algorithms are used for task scheduling in cloud environments in the literature such as Multi-Verse Optimizer (MVO) and Particle Swarm Optimization (PSO). In this paper, an Enhanced version of the Multi-Verse Optimizer (EMVO) is proposed as a superior task scheduler in this area. The proposed EMVO is compared with both original MVO and the PSO algorithms in cloud environments. The results show that EMVO substantially outperforms both MVO and PSO algorithms in terms of achieving minimized makespan time and increasing resources’ utilization.

Direct 3D Printing of Flexible Nasal Prosthesis: Optimized Digital Workflow from Scan to Fit

Abstract: A maxillofacial prosthesis is a successful treatment modality to restore missing facial parts. Digital technologies and 3D printing are employed in constructing facial prostheses such as ears; however, their application is still partial, and final prostheses are usually manufactured conventionally using stone molds. This report aims to introduce a complete digital workflow to construct a nasal prosthesis and compare it to the conventional workflow of a patient requiring a nasal prosthesis. A computer tomography scan showing the defect was exported to specialized software to create 3D reconstructions of the patient's face and underlying bone. The nose was digitally designed restoring facial esthetics, anatomy, shape, and skin color. Different skin tones were digitally matched to skin tissues adjacent to the defect area using the Spectromatch system. The design was 3D printed in flexible and colorful material at 16 μm resolution using a 3D printer. External color pigmentations were applied to the nose for optimum esthetics, and the prosthetic nose was sealed in silicone and left to heat polymerize for 15 minutes. The prosthetic nose was retained in place using biomedical adhesive, and the patient was pleased with it. This report proposes a complete digital workflow to directly design and fabricate a prosthetic nose of acceptable esthetics. Such a workflow can lead to enhanced prosthesis reproducibility and acceptability and may become an effective treatment option for treatment of patients with facial defects.