University of Kansas

About: University of Kansas is a education organization based out in Lawrence, Kansas, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 38183 authors who have published 81381 publications receiving 2986312 citations. The organization is also known as: KU & Univ of Kansas.

An ARIMA-Model-Based Approach to Seasonal Adjustment

Abstract: This article proposes a model-based procedure to decompose a time series uniquely into mutually independent additive seasonal, trend, and irregular noise components. The series is assumed to follow the Gaussian ARIMA model. Properties of the procedure are discussed and an actual example is given.

Adult Bone Marrow Cell Therapy Improves Survival and Induces Long-Term Improvement in Cardiac Parameters A Systematic Review and Meta-Analysis

Abstract: Background—Despite rapid clinical translation and widespread enthusiasm, the therapeutic benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart disease continue to remain controversial. A synthesis of the available data is critical to appreciate and underscore the true impact of this promising approach. Methods and Results—A total of 50 studies (enrolling 2625 patients) identified by database searches through January 2012 were included. Weighted mean differences for changes in left ventricular (LV) ejection fraction, infarct size, LV end-systolic volume, and LV end-diastolic volume were estimated with random-effects meta-analysis. Compared with control subjects, BMC-treated patients exhibited greater LV ejection fraction (3.96%; 95% confidence interval, 2.90–5.02; P<0.00001) and smaller infarct size (−4.03%, 95% confidence interval, −5.47 to −2.59; P<0.00001), LV end-systolic volume (−8.91 mL; 95% confidence interval, −11.57 to −6.25; P<0.00001), and LV end-diastolic volu...

Deep glacial troughs and stabilizing ridges unveiled beneath the margins of the Antarctic ice sheet

Abstract: The Antarctic ice sheet has been losing mass over past decades through the accelerated flow of its glaciers, conditioned by ocean temperature and bed topography. Glaciers retreating along retrograde slopes (that is, the bed elevation drops in the inland direction) are potentially unstable, while subglacial ridges slow down the glacial retreat. Despite major advances in the mapping of subglacial bed topography, significant sectors of Antarctica remain poorly resolved and critical spatial details are missing. Here we present a novel, high-resolution and physically based description of Antarctic bed topography using mass conservation. Our results reveal previously unknown basal features with major implications for glacier response to climate change. For example, glaciers flowing across the Transantarctic Mountains are protected by broad, stabilizing ridges. Conversely, in the marine basin of Wilkes Land, East Antarctica, we find retrograde slopes along Ninnis and Denman glaciers, with stabilizing slopes beneath Moscow University, Totten and Lambert glacier system, despite corrections in bed elevation of up to 1 km for the latter. This transformative description of bed topography redefines the high- and lower-risk sectors for rapid sea level rise from Antarctica; it will also significantly impact model projections of sea level rise from Antarctica in the coming centuries.