Institution
University of Louisville
Education•Louisville, Kentucky, United States•
About: University of Louisville is a education organization based out in Louisville, Kentucky, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 24600 authors who have published 49248 publications receiving 1573346 citations. The organization is also known as: UofL.
Topics: Population, Poison control, Transplantation, Cancer, Stem cell
Papers published on a yearly basis
Papers
More filters
TL;DR: In this trial involving patients with advanced heart failure who were ineligible for heart transplantation, a small, intrapericardial, centrifugal‐flow LVAD was found to be noninferior to an axial‐ flow LVAD with respect to survival free from disabling stroke or device removal for malfunction or failure.
Abstract: BackgroundMechanical circulatory support with a left ventricular assist device (LVAD) is an established treatment for patients with advanced heart failure. We compared a newer LVAD design (a small intrapericardial centrifugal-flow device) against existing technology (a commercially available axial-flow device) in patients with advanced heart failure who were ineligible for heart transplantation. MethodsWe conducted a multicenter randomized trial involving 446 patients who were assigned, in a 2:1 ratio, to the study (centrifugal-flow) device or the control (axial-flow) device. Adults who met contemporary criteria for LVAD implantation for permanent use were eligible to participate in the trial. The primary end point was survival at 2 years free from disabling stroke or device removal for malfunction or failure. The trial was powered to show noninferiority with a margin of 15 percentage points. ResultsThe intention-to treat-population included 297 participants assigned to the study device and 148 participan...
592 citations
Haidong Wang1, Zulfiqar A Bhutta2, Zulfiqar A Bhutta3, Matthew M Coates1 +610 more•Institutions (263)
TL;DR: The Global Burden of Disease 2015 Study provides an analytical framework to comprehensively assess trends for under-5 mortality, age-specific and cause-specific mortality among children under 5 years, and stillbirths by geography over time and decomposed the changes in under- 5 mortality to changes in SDI at the global level.
591 citations
University of Texas MD Anderson Cancer Center1, University Hospital of Basel2, Odense University Hospital3, Hoffmann-La Roche4, University of Louisville5, Aarhus University Hospital6, Memorial Sloan Kettering Cancer Center7, Cornell University8, Houston Methodist Hospital9, Columbia University Medical Center10, University of North Carolina at Chapel Hill11, Cleveland Clinic12, Li Ka Shing Faculty of Medicine, University of Hong Kong13, Zhejiang University14, Radboud University Nijmegen Medical Centre15, City of Hope National Medical Center16, Asan Medical Center17, University of California, San Francisco18, Southwest Washington Medical Center19, BC Cancer Research Centre20, Peking University21, Northwestern University22, Quest Diagnostics23
TL;DR: It is concluded that MYC/BCL2 coexpression in DLBCL is associated with an aggressive clinical course, is more common in the ABC subtype, and contributes to the overall inferior prognosis of patients with ABC-DLBCL.
584 citations
TL;DR: The death of superantigen-stimulated T cells in vivo is mediated by Bim and may be modulated by a decrease in Bcl-2, which is also found to be resistant to SEB-induced deletion.
583 citations
TL;DR: It is shown that bovine milk can serve as a scalable source of exosomes that can act as a carrier for chemotherapeutic/chemopreventive agents and ability to achieve tumor targetability.
576 citations
Authors
Showing all 24802 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Robert M. Califf | 196 | 1561 | 167961 |
| Aaron R. Folsom | 181 | 1118 | 134044 |
| Yang Gao | 168 | 2047 | 146301 |
| Stephen J. O'Brien | 153 | 1062 | 93025 |
| James J. Collins | 151 | 669 | 89476 |
| Anthony E. Lang | 149 | 1028 | 95630 |
| Sw. Banerjee | 146 | 1906 | 124364 |
| Hermann Kolanoski | 145 | 1279 | 96152 |
| Ferenc A. Jolesz | 143 | 631 | 66198 |
| Daniel S. Berman | 141 | 1363 | 86136 |
| Aaron T. Beck | 139 | 536 | 170816 |
| Kevin J. Tracey | 138 | 561 | 82791 |
| C. Dallapiccola | 136 | 1717 | 101947 |
| Michael I. Posner | 134 | 414 | 104201 |
| Alan Sher | 132 | 486 | 68128 |