Institution
University of São Paulo
Education•São Paulo, Brazil•
About: University of São Paulo is a education organization based out in São Paulo, Brazil. It is known for research contribution in the topics: Population & Context (language use). The organization has 136513 authors who have published 272320 publications receiving 5127869 citations. The organization is also known as: USP & Universidade de São Paulo.
Topics: Population, Context (language use), Medicine, Health care, Immune system
Papers published on a yearly basis
Papers
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TL;DR: The results indicate that succinate is an important substrate for isolated mitochondrial reactive oxygen production in brain, heart, kidney, and skeletal muscle, whereas fatty acids generate significant quantities of oxidants in kidney and liver.
380 citations
TL;DR: The immunologic and metabolic functions of AT macrophages and their different facets in obesity and the metabolic syndrome are reviewed.
Abstract: Immune cell infiltration in (white) adipose tissue (AT) during obesity is associated with the development of insulin resistance. In AT, the main population of leukocytes are macrophages. Macrophages can be classified into two major populations: M1, classically activated macrophages, and M2, alternatively activated macrophages, although recent studies have identified a broad range of macrophage subsets. During obesity, AT M1 macrophage numbers increase and correlate with AT inflammation and insulin resistance. Upon activation, pro-inflammatory M1 macrophages induce aerobic glycolysis. By contrast, in lean humans and mice, the number of M2 macrophages predominates. M2 macrophages secrete anti-inflammatory cytokines and utilize oxidative metabolism to maintain AT homeostasis. Here, we review the immunologic and metabolic functions of AT macrophages and their different facets in obesity and the metabolic syndrome.
380 citations
TL;DR: This paper examined the geographic distribution of biological diversity in the Atlantic Forest of South America, synthesized the most conspicuous forest biodiversity responses to human disturbances, and proposed further conservation initiatives for this biota, and offer a range of general insights into the prospects of forest species persistence in human-modified tropical forest landscapes worldwide.
380 citations
TL;DR: A systematic review and meta-analysis of tDCS studies targeting the DLPFC found that healthy participants respond faster, but not more accurate on cognitive tasks after a-tDCS, but increasing the current density and/or charge might be able to enhance response accuracy, particularly in females.
380 citations
TL;DR: The TIGGE project aims to facilitate closer cooperation between the academic and operational meteorological communities by expanding the availability of operational products for research and exploring the concept and benefits of multimodel probabilistic weather forecasts, with a particular focus on high-impact weather prediction.
Abstract: Ensemble forecasting is increasingly accepted as a powerful tool to improve early warnings for high-impact weather. Recently, ensembles combining forecasts from different systems have attracted a considerable level of interest. The Observing System Research and Predictability Experiment (THORPEX) Interactive Grand Globa l Ensemble (TIGGE) project, a prominent contribution to THORPEX, has been initiated to enable advanced research and demonstration of the multimodel ensemble concept and to pave the way toward operational implementation of such a system at the international level. The objectives of TIGGE are 1) to facilitate closer cooperation between the academic and operational meteorological communities by expanding the availability of operational products for research, and 2) to facilitate exploring the concept and benefits of multimodel probabilistic weather forecasts, with a particular focus on high-impact weather prediction. Ten operational weather forecasting centers producing daily global ensemble ...
380 citations
Authors
Showing all 138091 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| George M. Whitesides | 240 | 1739 | 269833 |
| Peter Libby | 211 | 932 | 182724 |
| Robert C. Nichol | 187 | 851 | 162994 |
| Paul M. Thompson | 183 | 2271 | 146736 |
| Terrie E. Moffitt | 182 | 594 | 150609 |
| Douglas R. Green | 182 | 661 | 145944 |
| Richard B. Lipton | 176 | 2110 | 140776 |
| Robin M. Murray | 171 | 1539 | 116362 |
| George P. Chrousos | 169 | 1612 | 120752 |
| David A. Bennett | 167 | 1142 | 109844 |
| Barry M. Popkin | 157 | 751 | 90453 |
| David H. Adams | 155 | 1613 | 117783 |
| Joao Seixas | 153 | 1538 | 115070 |
| Matthias Egger | 152 | 901 | 184176 |
| Ichiro Kawachi | 149 | 1216 | 90282 |