Institution
University of Warsaw
Education•Warsaw, Poland•
About: University of Warsaw is a education organization based out in Warsaw, Poland. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 20832 authors who have published 56617 publications receiving 1185084 citations. The organization is also known as: Uniwersytet Warszawski & Warsaw University.
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TL;DR: The data suggest that three different ribonucleases can serve as catalytic subunits for the exosome in human cells, and this work demonstrates the association of two different Dis3p homologs—hDIS3 and hDIS3L—with the humanExosome core.
Abstract: The eukaryotic RNA exosome is a ribonucleolytic complex involved in RNA processing and turnover. It consists of a nine-subunit catalytically inert core that serves a structural function and participates in substrate recognition. Best defined in Saccharomyces cerevisiae, enzymatic activity comes from the associated subunits Dis3p (Rrp44p) and Rrp6p. The former is a nuclear and cytoplasmic RNase II/R-like enzyme, which possesses both processive exo- and endonuclease activities, whereas the latter is a distributive RNase D-like nuclear exonuclease. Although the exosome core is highly conserved, identity and arrangements of its catalytic subunits in different vertebrates remain elusive. Here, we demonstrate the association of two different Dis3p homologs—hDIS3 and hDIS3L—with the human exosome core. Interestingly, these factors display markedly different intracellular localizations: hDIS3 is mainly nuclear, whereas hDIS3L is strictly cytoplasmic. This compartmental distribution reflects the substrate preferences of the complex in vivo. Both hDIS3 and hDIS3L are active exonucleases; however, only hDIS3 has retained endonucleolytic activity. Our data suggest that three different ribonucleases can serve as catalytic subunits for the exosome in human cells.
250 citations
TL;DR: In this article, a measurement of the H→ττ signal strength is performed using events recorded in proton-proton collisions by the CMS experiment at the LHC in 2016 at a center-of-mass energy of 13TeV.
250 citations
TL;DR: The NA48 experiment at CERN has performed a new measurement of direct CP violation, based on data taken in 1997 by simultaneously collecting KL and KS decays into π0π0 and π+π− as discussed by the authors.
249 citations
249 citations
University of Lisbon1, University of Cambridge2, Texas A&M University3, Florida State University4, Johns Hopkins University5, Argonne National Laboratory6, University of Wisconsin-Madison7, Lawrence Berkeley National Laboratory8, University of Vienna9, Stanford University10, Michigan State University11, Royal Holloway, University of London12, Moscow State University13, Fermilab14, Chonbuk National University15, CERN16, University of Freiburg17, Pontifical Catholic University of Chile18, University of Paris19, University of Delhi20, Austrian Academy of Sciences21, National Autonomous University of Mexico22, University of Würzburg23, University of Zurich24, Max Planck Society25, Indian Institute of Science26, Aristotle University of Thessaloniki27, University of Barcelona28, University of California, Davis29, University of Tokushima30, University of California, Santa Cruz31, University of Science and Technology of China32, Tsinghua University33, Uppsala University34, Tokyo Gakugei University35, Spanish National Research Council36, National Taiwan University37, University of Liverpool38, University of Warsaw39, University of Michigan40, Seoul National University41, Yonsei University42, University of Southampton43, University of Bonn44, University of Montpellier45, RWTH Aachen University46, Laboratoire d'Annecy-le-Vieux de physique des particules47, University of Pennsylvania48, Carleton University49, University of Florida50, University of Glasgow51, University of Tokyo52, University of Lyon53, Harish-Chandra Research Institute54, University of Colorado Boulder55, Kyoto University56, University of Minnesota57, University of Rochester58, Durham University59, Tata Institute of Fundamental Research60, Paul Scherrer Institute61, University of Hamburg62, Chung-Ang University63, University of Sheffield64, University of Chicago65, Tohoku University66, Peking University67
TL;DR: In this article, a supersymmetry Parameter Analysis SPA (SPA) scheme is proposed based on a consistent set of conventions and input parameters, which connect parameters in different schemes and relate the Lagrangian parameters to physical observables at LHC and high energy e+e-linear collider experiments.
Abstract: High-precision analyses of supersymmetry parameters aim at reconstructing the fundamental supersymmetric theory and its breaking mechanism. A well defined theoretical framework is needed when higher-order corrections are included. We propose such a scheme, Supersymmetry Parameter Analysis SPA, based on a consistent set of conventions and input parameters. A repository for computer programs is provided which connect parameters in different schemes and relate the Lagrangian parameters to physical observables at LHC and high energy e+e- linear collider experiments, i.e., masses, mixings, decay widths and production cross sections for supersymmetric particles. In addition, programs for calculating high-precision low energy observables, the density of cold dark matter (CDM) in the universe as well as the cross sections for CDM search experiments are included. The SPA scheme still requires extended efforts on both the theoretical and experimental side before data can be evaluated in the future at the level of the desired precision. We take here an initial step of testing the SPA scheme by applying the techniques involved to a specific supersymmetry reference point.
249 citations
Authors
Showing all 21191 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Alexander Malakhov | 139 | 1486 | 99556 |
| Emmanuelle Perez | 138 | 1550 | 99016 |
| Piotr Zalewski | 135 | 1388 | 89976 |
| Krzysztof Doroba | 133 | 1440 | 89029 |
| Hector F. DeLuca | 133 | 1303 | 69395 |
| Krzysztof M. Gorski | 132 | 380 | 105912 |
| Igor Golutvin | 131 | 1282 | 88559 |
| Jan Krolikowski | 131 | 1289 | 83994 |
| Michal Szleper | 130 | 1238 | 82036 |
| Anatoli Zarubin | 129 | 1204 | 86435 |
| Malgorzata Kazana | 129 | 1175 | 81106 |
| Artur Kalinowski | 129 | 1162 | 81906 |
| Predrag Milenovic | 129 | 1185 | 81144 |
| Marcin Konecki | 128 | 1178 | 79392 |
| Karol Bunkowski | 128 | 1192 | 79455 |