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Journal ArticleDOI

Basilar artery occlusion

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TLDR
If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken, however, the best treatment approach to improve clinical outcome still needs to be ascertained.
Abstract
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.

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Citations
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Journal ArticleDOI

Endovascular therapy for acute ischemic stroke: The standard of care.

TL;DR: Five trials in 2015 were completed demonstrating superior outcomes with intra-arterial therapy with improved results attributed to higher and faster rates of recanalization in a select patient population, which introduced a new standard of care in the management of acute ischemic stroke patients.
Journal ArticleDOI

Outcomes and Complications of Endovascular Mechanical Thrombectomy in the Treatment of Acute Posterior Circulation Occlusions: A Systematic Review

TL;DR: In patients with AIS caused by LVO of the posterior circulation, successful reperfusion can be achieved via EMT, with approximately a third of these patients achieving a good functional outcome.
Journal ArticleDOI

Vascular vertigo and dizziness: Diagnostic criteria

TL;DR: In this article , the diagnosis criteria for vascular vertigo and dizziness were formulated by the Committee for the Classification of Vestibular Disorders of the Bárány Society.
Journal ArticleDOI

Mechanical Thrombectomy in Basilar Artery Thrombosis: Technical Advances and Safety in a 10-Year Experience

TL;DR: High recanalization rates have been achieved since the introduction of MT in BAO, however, modern stent retriever and suction devices allow for safer and more rapid recansalization compared with previous MT devices.
Journal ArticleDOI

Recanalization is the Key for Better Outcome of Thrombectomy in Basilar Artery Occlusion

TL;DR: Patients with basilar artery occlusion were excluded from previous randomized controlled trials of endovascular treatment (ET) for acute ischemic stroke, but are commonly treated in clinical practice and predictors of functional outcome of ET in patients with BAO are analyzed to improve patient selection for ET.
References
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Journal ArticleDOI

The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease.

TL;DR: The results suggest the Penumbra System allows safe and effective revascularization in patients experiencing ischemic stroke secondary to large vessel occlusive disease who present within 8 hours from symptom onset.
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