Journal ArticleDOI
Basilar artery occlusion
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TLDR
If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken, however, the best treatment approach to improve clinical outcome still needs to be ascertained.Abstract:
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.read more
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Journal ArticleDOI
Current endovascular strategies for posterior circulation large vessel occlusion stroke: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee.
TL;DR: While many questions about pc-ELVO remain to be studied, there is evidence to support particular practices in its evaluation and treatment.
Journal ArticleDOI
Diagnostic and prognostic impact of pc-ASPECTS applied to perfusion CT in the basilar artery international cooperation study
Lars-Peder Pallesen,Johannes Gerber,Imanuel Dzialowski,Erik J.R.J. van der Hoeven,Patrik Michel,Thomas Pfefferkorn,Christoph Ozdoba,L. Jaap Kappelle,Baerbel Wiedemann,Andrei Khomenko,Ale Algra,Michael D. Hill,Ruediger von Kummer,Andrew M. Demchuk,Wouter J. Schonewille,Volker Puetz +15 more
TL;DR: The posterior circulation Acute Stroke Prognosis Early CT Score (pc‐APECTS) applied to CT angiography source images (CTA‐SI) predicts the functional outcome of patients in the Basilar Artery International Cooperation Study (BASICS).
Journal ArticleDOI
Posterior circulation cerebrovascular syndromes: diagnosis and management.
Ursula G. Schulz,Urs Fischer +1 more
TL;DR: The anatomy, aetiology and presentation of posterior circulation stroke is summarized, current approaches to management are discussed, and the preferred use of MRI for diagnosing posterior fossa lesions are discussed.
Journal ArticleDOI
Recanalization treatments in basilar artery occlusion—Systematic analysis:
Perttu J. Lindsberg,Tiina Sairanen,Simon Nagel,Oili Salonen,Heli Silvennoinen,Daniel Strbian +5 more
TL;DR: Endovascular mechanical approaches have been reported to provide superior outcomes over pharmacological thrombolysis in basilar artery occlusion andStricter patient selection would assist in translating excellent recanalization rates into improved clinical outcomes and more acceptable futility rates.
Journal ArticleDOI
Response to Late-Window Endovascular Revascularization Is Associated With Collateral Status in Basilar Artery Occlusion.
Fana Alemseged,Erik J.R.J. van der Hoeven,Francesca Di Giuliano,Darshan G Shah,Fabrizio Sallustio,Francesco Arba,Timothy Kleinig,Steven Bush,Richard Dowling,Bernard Yan,Gagan Sharma,Nicola Limbucci,Roberto Floris,Geoffrey A. Donnan,Volker Puetz,Marina Diomedi,Mark W Parsons,Peter Mitchell,Stephen M. Davis,Nawaf Yassi,Nawaf Yassi,Wouter J. Schonewille,Bruce C.V. Campbell +22 more
TL;DR: Revascularization is associated with good outcome in patients with basilar artery occlusion with good collaterals and less extensive occlusions, even >6 hours after onset.
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Journal ArticleDOI
The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease.
TL;DR: The results suggest the Penumbra System allows safe and effective revascularization in patients experiencing ischemic stroke secondary to large vessel occlusive disease who present within 8 hours from symptom onset.
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