Journal ArticleDOI
Basilar artery occlusion
TLDR
If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken, however, the best treatment approach to improve clinical outcome still needs to be ascertained.Abstract:
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.read more
Citations
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Journal ArticleDOI
The effects of aging on the functional and structural properties of the rat basilar artery
Nihal Tümer,Hale Z. Toklu,Judy M. Muller-Delp,Sehkar Oktay,Sehkar Oktay,Payal Ghosh,Kevin H. Strang,Michael D. Delp,Philip J. Scarpace +8 more
TL;DR: Findings indicate that aging produces dysfunction of both the endothelium and the vascular smooth muscle in the basilar artery, possibly through decreases in smooth muscle cell number and concomitant hypertrophy.
Journal ArticleDOI
Impact of stroke mechanism in acute basilar occlusion with reperfusion therapy
Woo Jin Lee,Kunhwa Jung,Kunhwa Jung,Young Jin Ryu,Jeong-Min Kim,Soon-Tae Lee,Soon-Tae Lee,Kon Chu,Kon Chu,Manho Kim,Manho Kim,Sang Kun Lee,Sang Kun Lee,Chul-Ho Sohn,Jae Kyu Roh +14 more
TL;DR: This work aimed to evaluate the impact of underlying mechanism of basilar artery (BA) occlusion on the outcomes after endovascular therapy for reperfusion and the outcome factors associated with each mechanism, and to identify radiologic parameters enabling to distinguish the underlying mechanism.
Journal ArticleDOI
Posterior Circulation Endovascular Thrombectomy for Large-Vessel Occlusion: Predictors of Favorable Clinical Outcome and Analysis of First-Pass Effect.
Andrea Alexandre,Iacopo Valente,Arturo Consoli,Mariangela Piano,Leonardo Renieri,J.D. Gabrieli,R. Russo,Antonio Armando Caragliano,Maria Ruggiero,Andrea Saletti,G Lazzarotti,Marco Pileggi,Nicola Limbucci,Mirco Cosottini,Amedeo Cervo,F. Viaro,Sergio Vinci,C. Commodaro,Fabio Pilato,Alessandro Pedicelli +19 more
TL;DR: In this article, the authors evaluated predictors of favorable clinical outcome and analyzed the effect of first-pass thrombectomy in 10 high-volume stroke centers in Europe, including the period from January 2016 to July 2019.
Journal ArticleDOI
Significance of angiographic clot meniscus sign in mechanical thrombectomy of basilar artery stroke.
TL;DR: The clot meniscus sign is related to high first pass effect and short procedure time and is a reliable predictor of successful recanalization in patients with acute BAO.
Journal ArticleDOI
Brainstem Strokes in Children: An 11-Year Series From a Tertiary Pediatric Center
TL;DR: Even with basilar artery occlusion and high stroke scales, outcome was good when systemic anticoagulation was started promptly, and magnetic resonance angiography was equivalent to digital subtractionAngiography for basilar arteries occlusions but not for vertebral artery dissection.
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The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease.
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