Journal ArticleDOI
Basilar artery occlusion
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TLDR
If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken, however, the best treatment approach to improve clinical outcome still needs to be ascertained.Abstract:
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.read more
Citations
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Journal ArticleDOI
Less thrombolysis in posterior circulation infarction-a necessary evil?
TL;DR: The clinical presentation, management, and outcome of PCI in the NORSTROKE registry is described, with a focus on posterior circulation infarction.
Journal ArticleDOI
Intracranial Stenting as Rescue Therapy After Failure of Mechanical Thrombectomy for Basilar Artery Occlusion: Data From the ANGEL-ACT Registry.
Gang Luo,Feng Gao,Xuelei Zhang,Baixue Jia,Xiaochuan Huo,Raynald Liu,Man Sum Chi,Man Sum Chi,Gaoting Ma,Guangge Peng,Jingyu Zhang,Zhongqi Qi,Xu Guo,Bin Han,Xu Tong,Bo Wang,Ligang Song,Lian Liu,Zijun He,Dapeng Mo,Ning Ma,Xuan Sun,Ming Yang,Zhongrong Miao +23 more
TL;DR: Wang et al. as discussed by the authors evaluated the safety and efficacy of rescue stenting following mechanical thrombectomy (MT) failure in patients with acute posterior circulation stroke due to basilar artery occlusion (BAO).
Journal ArticleDOI
Childhood acute basilar artery thrombosis successfully treated with mechanical thrombectomy using stent retrievers: case report and review of the literature.
Giancarlo Nicosia,Giancarlo Nicosia,Domenico Cicala,Giuseppe Mirone,Pietro Spennato,Vincenzo Trischitta,Claudio Ruggiero,Gianluigi Guarneri,Mario Muto,Giuseppe Cinalli +9 more
TL;DR: This case is the first case of basilar artery occlusion treated with Solitaire stent, in a child under 24 months, and indicates that basilar arteries recanalization in children can be achieved safely and with excellent clinical outcome using endovascular thrombectomy with the new generation self-expanding and retrievable stents.
Journal ArticleDOI
Intravenous alteplase at 0.6 mg/kg for acute stroke patients with basilar artery occlusion: the stroke acute management with urgent risk factor assessment and improvement (SAMURAI) Recombinant tissue plasminogen activator registry.
Tetsuya Miyagi,Masatoshi Koga,Yoshiaki Shiokawa,Jyoji Nakagawara,Yasuhiro Hasegawa,Eisuke Furui,Kazumi Kimura,Kazuomi Kario,Satoshi Okuda,Hiroshi Yamagami,Yasushi Okada,Tomohisa Nezu,Koichiro Maeda,Kaoru Endo,Kazuo Minematsu,Kazunori Toyoda +15 more
TL;DR: The use of low-dose alteplase resulted in similar outcomes when comparing acute BAO and MCO patients, and vital and functional outcomes at 3 months were relatively better in this study.
Journal ArticleDOI
A Pre-Intervention 4-Item Scale for Predicting Poor Outcome Despite Successful Recanalization in Basilar Artery Occlusion
TL;DR: As a pre-intervention predictive model, the 4-item scale has promising predictive value for poor outcome despite successful recanalization in BAO patients treated with EVT, Nevertheless, external validation with blinded outcome is still needed to confirm its performance before clinical application.
References
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Journal ArticleDOI
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TL;DR: Higher rates of recanalization were associated with a newer generation thrombectomy device compared with first-generation devices, but these differences did not achieve statistical significance.
Journal ArticleDOI
The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease.
TL;DR: The results suggest the Penumbra System allows safe and effective revascularization in patients experiencing ischemic stroke secondary to large vessel occlusive disease who present within 8 hours from symptom onset.
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