Journal ArticleDOI
Basilar artery occlusion
TLDR
If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken, however, the best treatment approach to improve clinical outcome still needs to be ascertained.Abstract:
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.read more
Citations
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Journal ArticleDOI
Mechanical thrombectomy with the Solitaire AB stent for treatment of acute basilar artery occlusion: A single-center experience.
Shiwei Du,Gengsheng Mao,Dongmei Li,Ming Qiu,Qingbin Nie,Haibo Zhu,Yang Yang,You-ping Zhang,Youxiang Li,Zhongxue Wu +9 more
TL;DR: Application of the Solitaire AB stent retriever in acute BAO resulted in a high recanalization rate without procedural complications, and with good clinical outcome, and further prospective trials are needed to confirm the potential clinical benefit of this treatment approach.
Journal ArticleDOI
Outcomes in Endovascular Therapy for Basilar Artery Occlusion: Intracranial Atherosclerotic Disease vs. Embolism.
Longfei Wu,Gary B Rajah,Eric E Cosky,Xiling Wu,Chuanhui Li,Jian Chen,Wenbo Zhao,Di Wu,Yuchuan Ding,Xunming Ji +9 more
TL;DR: Wang et al. as discussed by the authors explored the impact of the underlying pathological mechanisms on prognosis at 90-days and long-term follow-up in BAO patients treated with endovascular therapy (EVT).
Journal ArticleDOI
Implications of Mechanical Endovascular Thrombectomy for Acute Basilar and Posterior Cerebral Artery Occlusion
Hyun-Nyung Lee,Bum-Tea Kim,Soo Bin Im,Sun-Chul Hwang,Je-Hoon Jeong,Moonyoung Chung,Jong-Hyun Park,Dong-Seong Shin +7 more
TL;DR: In this article, the authors investigated the medical records of patients who underwent MET for posterior circulation ischemic stroke from January 2012 to August 2016, in patients with or without injected intravenous tissue plasminogen activator.
Journal ArticleDOI
DWI-pc-ASPECT score in basilar artery occlusion: is 6 points or less always indicative of a bad outcome?
TL;DR: Even with DWI-pc-ASPECTS of 6 or less, good clinical outcome can be achieved after endovascular reperfusion therapy, and in patients aged over 70 years, a favourable outcome was low, even after successful recanalisation.
Journal ArticleDOI
Clinical Outcomes of Patients with Acute Basilar Artery Occlusion in Brazil: An Observational Study.
Francisco Antunes Dias,Frederico F Alessio-Alves,Luis Henrique de Castro-Afonso,Pedro Cougo,Clara Monteiro Antunes Barreira,Millene Rodrigues Camilo,Guilherme Seizem Nakiri,Daniel Giansante Abud,Octavio M. Pontes-Neto +8 more
TL;DR: BAO is associated with high morbidity and mortality in patients with acute basilar artery occlusion in Brazil and access to acute recanalization therapies may decrease mortality in those patients.
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The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease.
TL;DR: The results suggest the Penumbra System allows safe and effective revascularization in patients experiencing ischemic stroke secondary to large vessel occlusive disease who present within 8 hours from symptom onset.
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