Journal ArticleDOI
Basilar artery occlusion
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TLDR
If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken, however, the best treatment approach to improve clinical outcome still needs to be ascertained.Abstract:
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.read more
Citations
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Journal ArticleDOI
Bridging versus direct endovascular therapy in basilar artery occlusion.
Sergio Nappini,Francesco Arba,Giovanni Pracucci,Valentina Saia,Danilo Caimano,Nicola Limbucci,Leonardo Renieri,Andrea Zini,Domenico Inzitari,Danilo Toni,Salvatore Mangiafico +10 more
TL;DR: In this article, the authors evaluated safety and efficacy of intravenous recombinant tissue Plasminogen Activator plus endovascular (bridging) therapy in patients with acute ischaemic stroke due to basilar artery occlusion (BAO).
Journal ArticleDOI
A New Era of Extended Time Window Acute Stroke Interventions Guided by Imaging.
Bhavya Rehani,Simon G Ammanuel,Yi Zhang,Wade S. Smith,Daniel L Cooke,Steven W. Hetts,S. Andrew Josephson,Anthony S. Kim,J. Claude Hemphill,William P. Dillon +9 more
TL;DR: The advanced imaging algorithm for ischemic stroke workup is reviewed in the multiple studies published to date and the results of the clinical trials for late ischeic stroke that can be clinically useful are summarized.
Journal ArticleDOI
Outcome and recanalization rate of tandem basilar artery occlusion treated by mechanical thrombectomy.
Mahmoud Elhorany,Gregoire Boulouis,Wagih Ben Hassen,Sophie Crozier,Eimad Shotar,Nader-Antoine Sourour,Stéphanie Lenck,Kevin Premat,Robert Fahed,Vincent Degos,Ahmed Mohamed Elhfnawy,Ossama Mansour,El-Sayed Ali Tag El-din,Wael Fadel,Sonia Alamowitch,Yves Samson,Olivier Naggara,Frédéric Clarençon +17 more
TL;DR: Mechanical thrombectomy for patients with tandem basilar artery occlusion tends to be associated with lower rates of successful reperfusion and good clinical outcome, and higher rate of mortality.
Journal ArticleDOI
Childhood basilar artery occlusion: a report of 5 cases and review of the literature.
Mahesh Chikkannaiah,Warren D. Lo +1 more
TL;DR: There was strong correlation between the NIHSS and the mRS, and certain children with basilar artery occlusion may be treated conservatively and have better outcomes than adults.
Journal ArticleDOI
Predictors of Early Neurological Deterioration in Stroke Due to Vertebrobasilar Occlusion.
TL;DR: In this article, the authors explored the predictors of early neurological deterioration in patients with vertebrobasilar occlusion (VBO) in both primary endovascular therapy (EVT) and medical management (MM) groups.
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Journal ArticleDOI
Mechanical Thrombectomy for Acute Ischemic Stroke: Final Results of the Multi MERCI Trial
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TL;DR: Higher rates of recanalization were associated with a newer generation thrombectomy device compared with first-generation devices, but these differences did not achieve statistical significance.
Journal ArticleDOI
The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease.
TL;DR: The results suggest the Penumbra System allows safe and effective revascularization in patients experiencing ischemic stroke secondary to large vessel occlusive disease who present within 8 hours from symptom onset.
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