Journal ArticleDOI
Basilar artery occlusion
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TLDR
If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken, however, the best treatment approach to improve clinical outcome still needs to be ascertained.Abstract:
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.read more
Citations
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Journal ArticleDOI
Acute Symptomatic Basilar Artery Stenosis: MR Imaging Predictors of Early Neurologic Deterioration and Long-term Outcomes.
Woo Jin Lee,Keun-Hwa Jung,Young Jin Ryu,Keon-Joo Lee,Soon-Tae Lee,Kon Chu,Sang Kun Lee,Jae-Kyu Roh +7 more
TL;DR: In medically treated symptomatic BAS, MR imaging parameters such as proximal basilar FHV and DW imaging-based pc-ASPECTS have independent prognostic values for END development and long-term outcomes.
Journal ArticleDOI
Computed Tomography Perfusion Deficit Volumes Predict Functional Outcome in Patients With Basilar Artery Occlusion.
Matthias P. Fabritius,Steffen Tiedt,Daniel Puhr-Westerheide,Sergio Grosu,Stefan Maurus,Vincent Schwarze,Johannes Rübenthaler,Lena Stueckelschweiger,Jens Ricke,Thomas Liebig,Lars Kellert,Katharina Feil,Konstantinos Dimitriadis,Wolfgang G. Kunz,Paul Reidler +14 more
TL;DR: CTP imaging parameters contain prognostic information for functional outcome in patients with stroke due to basilar artery occlusion and may identify patients with higher risk of disability at an early stage of hospitalization.
Journal ArticleDOI
Endovascular revascularization for basilar artery occlusion.
TL;DR: This review examines the approaches to stroke syndromes due to basilar artery thrombosis for intravenous and intra-arterial tissue plasminogen activator as well as mechanical approaches to restoring perfusion in this critical area of the brain.
Journal ArticleDOI
Thrombus Histology of Basilar Artery Occlusions : Are There Differences to the Anterior Circulation?
Maria Berndt,Holger Poppert,K. Steiger,J. Pelisek,J. Pelisek,Paul Oberdieck,Christian Maegerlein,Claus Zimmer,Silke Wunderlich,Benjamin Friedrich,Tobias Boeckh-Behrens,Benno Ikenberg +11 more
TL;DR: The results depict a differing thrombus composition of basilar thrombi in comparison to anterior circulation clots with an overall higher amount of RBC, which may reflect different pathophysiologic processes between anterior and posterior circulation thrombogenesis.
Journal ArticleDOI
Evolving Role of Endovascular Treatment of Acute Ischemic Stroke
TL;DR: The available evidence does not provide support for the use of endovascular treatment of acute ischemic stroke in clinical practice, and the new challenge is how to study the latest generation of devices called stent retrievers, which are faster in recanalizing and easier to use, in selected patients with acute isChemic stroke.
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TL;DR: Higher rates of recanalization were associated with a newer generation thrombectomy device compared with first-generation devices, but these differences did not achieve statistical significance.
Journal ArticleDOI
The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease.
TL;DR: The results suggest the Penumbra System allows safe and effective revascularization in patients experiencing ischemic stroke secondary to large vessel occlusive disease who present within 8 hours from symptom onset.
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