Journal ArticleDOI
Basilar artery occlusion
TLDR
If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken, however, the best treatment approach to improve clinical outcome still needs to be ascertained.Abstract:
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.read more
Citations
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Journal ArticleDOI
Acute ischemic stroke treatment using mechanical thrombectomy: A study of 137 patients
Rakeshsingh K Singh,Vishal Annaji Chafale,Rakesh Shyam Lalla,Keyurkumar Chandrakantbhai Panchal,Anil Pandurang Karapurkar,Satish V Khadilkar,Pawan K Ojha,Yogesh Godge,Rakesh K. Singh,Rajesh Benny +9 more
TL;DR: With careful patient selection, clinical outcome in PC was comparable to AC despite delayed presentation and higher baseline NIHSS, which is associated with significant better clinical outcome at 3 months.
Journal ArticleDOI
Initial Assessment and Triage of the Stroke Patient
TL;DR: Intravenous tissue plasminogen activator is recommended for all qualified patients and patients with presentations suggesting large vessel occlusion should be evaluated for mechanical thrombectomy and intravenous thrombolysis for ischemic stroke.
Journal ArticleDOI
A novel route of revascularization in basilar artery occlusion and review of the literature
TL;DR: In this paper, the authors describe the first report of retrograde vertebral artery (VA) revascularization using thyrocervical collaterals for anterograde mechanical aspiration of a BAO followed by stenting of the chronically occluded VA origin.
Journal ArticleDOI
ADC quantification in basilar artery occlusion as an indicator of clinical outcome after endovascular treatment.
TL;DR: ADC quantification of ischemic lesions at baseline MRI seems to predict clinical outcome in patients with BAO undergoing EVT, more importantly than isChemic area or TICI grade.
Journal ArticleDOI
Acute Basilar Artery Occlusion: Does Recanalization Improve Clinical Outcome? A Critically Appraised Topic.
TL;DR: IVT is the standard of care for BAO patients presenting within 4.5 hours of symptom onset, whereas recanalization is associated with better outcomes regardless of how recanality is achieved, according to a recent meta-analysis.
References
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Journal ArticleDOI
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Journal ArticleDOI
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Journal ArticleDOI
The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease.
TL;DR: The results suggest the Penumbra System allows safe and effective revascularization in patients experiencing ischemic stroke secondary to large vessel occlusive disease who present within 8 hours from symptom onset.
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