Journal ArticleDOI
Basilar artery occlusion
TLDR
If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken, however, the best treatment approach to improve clinical outcome still needs to be ascertained.Abstract:
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or MRI, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.read more
Citations
More filters
Journal ArticleDOI
Effect of Baseline Characteristics on the Outcome of Stent Retriever-Based Thrombectomy in Acute Basilar Artery Occlusions: A Single-Center Experience and Pooled Data Analysis.
Wanling Wen,Zifu Li,Yongwei Zhang,Pengfei Yang,Keith Simfukwe,Yibin Fang,Tian-Yi Zhang,Ben-Qiang Deng,Bo Hong,Jianmin Liu,Qinghai Huang +10 more
TL;DR: SRT with or without additional treatment appeared to be effective for the treatment of BAO, and successful reperfusion, distal segment occlusion, and cardiac embolism were associated with favorable outcome.
Journal ArticleDOI
Utility of digital subtraction angiography-based collateral evaluation in medically treated acute symptomatic basilar artery stenosis.
Woo Jin Lee,Kunhwa Jung,Kunhwa Jung,Young Jin Ryu,Jeong-Min Kim,Soon-Tae Lee,Soon-Tae Lee,Kon Chu,Kon Chu,Manho Kim,Manho Kim,Sang Kun Lee,Sang Kun Lee,Jae-Kyu Roh +13 more
TL;DR: This work investigated the efficacy of digital subtraction angiography (DSA)‐based collateral perfusion evaluation in association with long‐term outcomes of medically treated symptomatic basilar artery stenosis.
Journal ArticleDOI
Valor de la escala ASPECTS de circulación posterior y del índice puente-mesencéfalo en imágenes de TC sin contraste y angiografía por TC en pacientes con oclusiones de la arteria basilar recanalizados tras trombectomía mecánica
Mariano Werner,Antonio López-Rueda,Federico Zarco,Jordi Blasco,L. San Román,Sergio Amaro,Enrique Carrero,Ricard Valero,Laura Oleaga,Juan Macho,Núria Bargalló +10 more
TL;DR: Un objetivo principal de nuestro estudio fue hacer una valoracion del valor pronostico de la escala ASPECTS y del indice puente-mesencefalo en pacientes con oclusiones de the arteria basilar, sometidos, con exito, a recanalizacion angiografica tras trombectomia mecanica.
Journal ArticleDOI
Successful endovascular recanalization of a partially occluded basilar artery fenestration.
TL;DR: A 76-year-old man with a history of arterial hypertension, obstructive sleep apnea, dyslipidemia, family history of cardiovascular events, prestroke and overweight was presented 90 minutes after acute onset of right-sided sensorimotor hemiparesis, hemiataxia and dysarthria.
Journal ArticleDOI
DWI cerebellar infarct volume as predictor of outcomes after endovascular treatment of acute basilar artery occlusion.
Isabelle Mourand,Mehdi Mahmoudi,Cyril Dargazanli,Frederique Pavillard,Caroline Arquizan,Julien Labreuche,Imad Derraz,Nicolas Gaillard,Genevieve Blanchet-Fourcade,Pierre-Henri Lefevre,Yassine Boukriche,Gregory Gascou,Lucas Corti,Vincent Costalat,Emmanuelle Le Bars,Federico Cagnazzo +15 more
TL;DR: In a series of MRI-selected patients with ABAO, pre-EVT CIV was an independent predictor of 90-day mortality and the risk of death was increased for baseline CIV ≥4.7 mL.
References
More filters
Journal ArticleDOI
Guidelines for management of ischaemic stroke and transient ischaemic attack 2008
Peter A. Ringleb,Marie-Germaine Bousser,Gary A. Ford,Philip M.W. Bath,Michael Brainin,Valeria Caso,Álvaro Cervera,Ángel Chamorro,Charlotte Cordonnier,László Csiba,Antoni Dávalos,Hans-Christoph Diener,José M. Ferro,Werner Hacke,Michael G. Hennerici,Markku Kaste,Peter Langhorne,Kennedy R. Lees,Didier Leys,J. Lodder,Hugh S. Markus,Jean-Louis Mas,Heinrich Mattle,Keith W. Muir,Bo Norrving,Victor Obach,Stefano Paolucci,E. Bernd Ringelstein,Peter D. Schellinger,Juhani Sivenius,Skvortsova Vi,Katharina S. Sunnerhagen,Lars Thomassen,Danilo Toni,Rüdiger von Kummer,Nils Wahlgren,Marion F Walker,Joanna M. Wardlaw +37 more
TL;DR: The article covers referral and emergency management, Stroke Unit service, diagnostics, primary and secondary prevention, general stroke treatment, specific treatment including acute management, management of complications, and rehabilitation.
Journal ArticleDOI
Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials.
Kennedy R. Lees,Erich Bluhmki,Rüdiger von Kummer,Thomas G. Brott,Danilo Toni,James C. Grotta,Gregory W. Albers,Markku Kaste,John R. Marler,Scott Hamilton,Barbara C. Tilley,Stephen M. Davis,Geoffrey A. Donnan,Werner Hacke +13 more
TL;DR: Patients with ischaemic stroke selected by clinical symptoms and CT benefit from intravenous alteplase when treated up to 4.5 h should be taken to shorten delay in initiation of treatment to increase benefit to a maximum.
Journal ArticleDOI
The International Stroke Trial (IST): A randomised trial of aspirin, subcutaneous heparin, both, or neither among 19 435 patients with acute ischaemic stroke
Peter Sandercock,Rory Collins,Carl Counsell,Barbara Farrell,Richard Peto,Jim Slattery,Charles Warlow,S Anderson,A Bowie,J Boyle,A Brownlie,D Charlton,Gina Cranswick,L Day,Martin Dennis,Paul Dorman,H Fraser,M Kaye,Richard I. Lindley,M Liu,C MacDonald,I McCrindle,G Middleton,D. Perry,V Scoltock,Brenda Smith,Hugh R. Taylor,Fiona Waddell,Joanna Wardlaw,J Crowther,J Heineman,S Knight,Andrew Radley,R Ripley,S Richards,S Wilberforce,Zhengming Chen,J vanGijn,Michael R. Harrison,Lars Wilhelmsen +39 more
TL;DR: Aspirinallocated patients had significantly fewer recurrent ischaemic strokes within 14 days with no significant excess of haemorrhagic strokes, so the reduction in death or non-fatal recurrent stroke with aspirin was significant.
Journal ArticleDOI
Mechanical Thrombectomy for Acute Ischemic Stroke: Final Results of the Multi MERCI Trial
Wade S. Smith,Gene Sung,Jeffrey L. Saver,Ronald F. Budzik,Gary Duckwiler,David S Liebeskind,Helmi L. Lutsep,Marilyn M. Rymer,Randall T. Higashida,Sidney Starkman,Y. Pierre Gobin +10 more
TL;DR: Higher rates of recanalization were associated with a newer generation thrombectomy device compared with first-generation devices, but these differences did not achieve statistical significance.
Journal ArticleDOI
The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease.
TL;DR: The results suggest the Penumbra System allows safe and effective revascularization in patients experiencing ischemic stroke secondary to large vessel occlusive disease who present within 8 hours from symptom onset.
Related Papers (5)
Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study.
Wouter J. Schonewille,Christine A. C. Wijman,Patrik Michel,Christina Rueckert,Christian Weimar,Heinrich Mattle,Stefan T. Engelter,David Tanne,Keith W. Muir,Carlos A. Molina,Vincent Thijs,Heinrich Audebert,Thomas Pfefferkorn,Kristina Szabo,Perttu J. Lindsberg,Gabriel R. de Freitas,L. Jaap Kappelle,Ale Algra +17 more
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
Mayank Goyal,Bijoy K Menon,Wim H. van Zwam,Diederik W.J. Dippel,Peter Mitchell,Andrew M. Demchuk,Antoni Dávalos,Charles B. L. M. Majoie,Aad van der Lugt,Maria Angeles De Miquel,Geoffrey A. Donnan,Yvo B.W.E.M. Roos,Alain Bonafe,Reza Jahan,Hans-Christoph Diener,Lucie A. van den Berg,Elad I. Levy,Olvert A. Berkhemer,Vitor Mendes Pereira,Jeremy L. Rempel,Mónica Millán,Stephen M. Davis,Daniel Roy,John Thornton,Luis San Roman,Marc Ribo,Debbie Beumer,Bruce Stouch,Scott Brown,Bruce C.V. Campbell,Robert J. van Oostenbrugge,Jeffrey L. Saver,Michael D. Hill,Tudor G Jovin +33 more