Open Access
Common values in assessing health outcomes from disease and injury: Disability weights measurement study for the Global Burden of Disease Study 2010
Joshua A. Salomon,Theo Vos,Daniel R Hogan,Michael L. Gagnon,Mohsen Naghavi,Ali H. Mokdad,Nazma Begum,Ravi V. Shah,Muhammad Karyana,Soewarta Kosen,M.R. Farje,G. Moncada,Arup Dutta,Sunil Sazawal,Anthony Dyer,Jason F. S. Seiler,Victor Aboyans,L. Baker,Amanda J Baxter,Emelia J. Benjamin,Kavi Bhalla,Aref A. Bin Abdulhak,Fiona M. Blyth,Rupert R A Bourne,Tasanee Braithwaite,Peter Brooks,Traolach S. Brugha,Claire Bryan-Hancock,Rachelle Buchbinder,Peter Burney,Bianca Calabria,Honglei Chen,Sumeet S. Chugh,R. Cooley,Michael H. Criqui,Marita Cross,Kaustubh Dabhadkar,Nabila Dahodwala,Adrian Davis,Louisa Degenhardt,Cesar Diaz-Torne,E. R. Dorsey,Tim Driscoll,Karen Edmond,Alexis Elbaz,Majid Ezzati,Valery L. Feigin,Cleusa P. Ferri,Abraham D. Flaxman,Louise Flood,Marlene Fransen,K. Fuse,Belinda J. Gabbe,Richard F. Gillum,Juanita A. Haagsma,James Harrison,Rasmus Havmoeller,Roderick J. Hay,A. Hel-Baqui,Hans W. Hoek,Howard J. Hoffman,E. Hogeland,Damian G Hoy,Deborah Jarvis,Ganesan Karthikeyan,Lisa M. Knowlton,Tim Lathlean,Janet L Leasher,Stephen S Lim,Steven E. Lipshultz,Alan D. Lopez,Rafael Lozano,Ronan A Lyons,Reza Malekzadeh,Wagner Marcenes,Lyn March,David J. Margolis,Neil McGill,John J. McGrath,George A. Mensah,A.C. Meyer,Catherine Michaud,Andrew E. Moran,Rintaro Mori,M. E. Murdoch,Luigi Naldi,Charles R. Newton,Rosana E. Norman,Saad B. Omer,Richard H. Osborne,Neil Pearce,Fernando Perez-Ruiz,Norberto Perico,Konrad Pesudovs,David Phillips,Farshad Pourmalek,Martin Prince,Jürgen Rehm,G. Remuzzi,Kathryn Richardson,Robin Room,Sukanta Saha,Uchechukwu Sampson,Lidia Sanchez-Riera,Maria Segui-Gomez,Saeid Shahraz,Kenji Shibuya,Deo Singh,Karen Sliwa,Emma Smith,Isabelle Soerjomataram,Timothy J. Steiner,Wilma A. Stolk,Lars Jacob Stovner,Christopher R. Sudfeld,Hugh R. Taylor,Imad M. Tleyjeh,M.J. Van Der Werf,W.L. Watson,David J. Weatherall,Robert G. Weintraub,Marc G. Weisskopf,Harvey Whiteford,James D. Wilkinson,Anthony D. Woolf,Zhi Jie Zheng,Christopher J L Murray +126 more
TLDR
This study represents the most extensive empirical effort as yet to measure disability weights and reports strong evidence of highly consistent results.Abstract:
NOTE: This article is free to read on the journal website provided you register (which is free).
BACKGROUND
Measurement of the global burden of disease with disability-adjusted life-years (DALYs) requires disability weights that quantify health losses for all non-fatal consequences of disease and injury. There has been extensive debate about a range of conceptual and methodological issues concerning the definition and measurement of these weights. Our primary objective was a comprehensive re-estimation of disability weights for the Global Burden of Disease Study 2010 through a large-scale empirical investigation in which judgments about health losses associated with many causes of disease and injury were elicited from the general public in diverse communities through a new, standardised approach.
METHODS
We surveyed respondents in two ways: household surveys of adults aged 18 years or older (face-to-face interviews in Bangladesh, Indonesia, Peru, and Tanzania; telephone interviews in the USA) between Oct 28, 2009, and June 23, 2010; and an open-access web-based survey between July 26, 2010, and May 16, 2011. The surveys used paired comparison questions, in which respondents considered two hypothetical individuals with different, randomly selected health states and indicated which person they regarded as healthier. The web survey added questions about population health equivalence, which compared the overall health benefits of different life-saving or disease-prevention programmes. We analysed paired comparison responses with probit regression analysis on all 220 unique states in the study. We used results from the population health equivalence responses to anchor the results from the paired comparisons on the disability weight scale from 0 (implying no loss of health) to 1 (implying a health loss equivalent to death). Additionally, we compared new disability weights with those used in WHO's most recent update of the Global Burden of Disease Study for 2004.
FINDINGS
13,902 individuals participated in household surveys and 16,328 in the web survey. Analysis of paired comparison responses indicated a high degree of consistency across surveys: correlations between individual survey results and results from analysis of the pooled dataset were 0·9 or higher in all surveys except in Bangladesh (r=0·75). Most of the 220 disability weights were located on the mild end of the severity scale, with 58 (26%) having weights below 0·05. Five (11%) states had weights below 0·01, such as mild anaemia, mild hearing or vision loss, and secondary infertility. The health states with the highest disability weights were acute schizophrenia (0·76) and severe multiple sclerosis (0·71). We identified a broad pattern of agreement between the old and new weights (r=0·70), particularly in the moderate-to-severe range. However, in the mild range below 0·2, many states had significantly lower weights in our study than previously.
INTERPRETATION
This study represents the most extensive empirical effort as yet to measure disability weights. By contrast with the popular hypothesis that disability assessments vary widely across samples with different cultural environments, we have reported strong evidence of highly consistent results.read more
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Journal Article
Characterizing the epidemiological transition in Mexico: National and subnational burden of diseases, injuries, and risk factors (vol 5, pg e125, 2008)
Gretchen A Stevens,Rodrigo H Dias,Kevin J. A. Thomas,Juan A Rivera,Natalie Carvalho,Simón Barquera,Kenneth Hill,Majid Ezzati +7 more
TL;DR: A unique characteristic of the epidemiological transition in Mexico is that overweight and obesity, high blood glucose, and alcohol use are responsible for larger burden of disease than other noncommunicable disease risks such as tobacco smoking.
Journal ArticleDOI
Migraine
Michel D. Ferrari,Peter J. Goadsby,Rami Burstein,Tobias Kurth,Cenk Ayata,Andrew Charles,Messoud Ashina,Arn M. J. M. van den Maagdenberg,David W. Dodick +8 more
TL;DR: This Primer by Ferrari and colleagues summarizes the epidemiology, pathophysiology, diagnosis and treatment of migraine, and quality of life issues faced by patients with migraine and future research avenues are discussed.
Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: Quantifying the epidemiological transition
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TL;DR: The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age-sex groups, and countries as discussed by the authors.
Journal ArticleDOI
Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
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Kemp Bohan,Mohammad Keykhaei,Yousef Khader,Himanshu Khajuria,Gulfaraz Khan,Imteyaz Ahmad Khan,Junaid Khan,Moien Ab Khan,Javad Khanali,Amir Khater,Mahalaqua Nazli Khatib,Mahmoud Khodadost,Abdullah T Khoja,Omid Khosravizadeh,Jagdish Khubchandani,Gyu Ri Kim,Hanna Kim,Min Seo Kim,Yun Jin Kim,Jonathan M. Kocarnik,Ali-Asghar Kolahi,Rajasekaran Koteeswaran,G Anil Kumar,Carlo La Vecchia,Dharmesh Kumar Lal,Iván Landires,Savita Lasrado,Jeffrey V. Lazarus,Caterina Ledda,Doo Woong Lee,Sang-Woong Lee,Yeong Yeh Lee,Miriam Levi,Jiarui Li,Stephen S Lim,Stany W. Lobo,Platon D. Lopukhov,Joana A. Loureiro,Jennifer H MacLachlan,Hassan Magdy Abd El Razek,Muhammed Magdy Abd El Razek,Azeem Majeed,Alaa Makki,Mohammad-Reza Malekpour,Reza Malekzadeh,Ahmad Azam Malik,Fariborz Mansour-Ghanaei,Mohammad Ali Mansournia,Francisco Rogerlândio Martins-Melo,Philippa C Matthews,Walter Mendoza,Ritesh G. Menezes,Tuomo J. Meretoja,Amanual Getnet Mersha,Tomislav Mestrovic,Ted R. Miller,Le H. Minh,Andreea Mirică,Seyyedmohammadsadeq Mirmoeeni,Erkin M. Mirrakhimov,Sarthak Misra,Prasanna Mithra,Babak Moazen,Ashraf Mohamadkhani,Mokhtar Mohammadi,Shafiu Mohammed,Nagabhishek Moka,Ali H. Mokdad,Jalal Moludi,Sara Momtazmanesh,Lorenzo Monasta,Ghobad Moradi,Maliheh Moradzadeh,Rahmatollah Moradzadeh,Paula Moraga,E Mostafavi,Sumaira Mubarik,M Muniyandi,Christopher J L Murray,Mohsen Naghavi,Mukhammad David Naimzada,Sreenivas Narasimha Swamy,Zuhair S. Natto,Biswa Prakash Nayak,Javad Nazari,Ionut Negoi,Serban Negru,Seyed Aria Nejadghaderi,Sandhya Neupane Kandel,Huong Lan Thi Nguyen,Che Henry Ngwa,Robina Niazi,Chukwudi A Nnaji,Jean Jacques Noubiap,Ali A. Nowroozi,Virginia Núñez-Samudio,Bogdan Oancea,C Ochir,Oluwakemi Ololade Odukoya,In-Hwan Oh,Andrew T Olagunju,Babayemi O Olakunde,Ahmed Omar Bali,Emad Omer,Stanislav S. Otstavnov,Bilcha Oumer,Jagadish Rao Padubidri,Adrian Pana,Anamika Pandey,Eun Cheol Park,Fatemeh Pashazadeh Kan,Urvish K Patel,Uttam Paudel,Ionela-Roxana Petcu,Zahra Zahid Piracha,Richard Pollok,Maarten J. Postma,Akram Pourshams,Hossein Poustchi,Mohammad Rabiee,Navid Rabiee,Alireza Rafiei,Sima Rafiei,Pavan Manibettu Raghuram,Mosiur Rahman,Amir Masoud Rahmani,Setyaningrum Rahmawaty,Aashish Rajesh,Priyanga Ranasinghe,Chythra R Rao,Sowmya J. Rao,Mahsa Rashidi,Mohammad Mahdi Rashidi,David Laith Rawaf,Salman Rawaf,Reza Rawassizadeh,Negar Rezaei,Aziz Rezapour,Sahba Rezazadeh-Khadem,Jefferson A. Buendía Rodriguez,Godfrey Mutashambara Rwegerera,Siamak Sabour,Basema Saddik,Mohammad Reza Saeb,Umar Saeed,Amirhossein Sahebkar,K. M. Saif-Ur-Rahman,Sarvenaz Salahi,Hamideh Salimzadeh,Chethan Sampath,Abdallah M. Samy,Juan Sanabria,Francesco Sanmarchi,Milena Santric-Milicevic,Arash Sarveazad,Brijesh Sathian,Monika Sawhney,Abdul-Aziz Seidu,Sadaf G. Sepanlou,Allen Seylani,Saeed Shahabi,Masood Ali Shaikh,Elaheh Shaker,Murad Z. Shakhmardanov,Mohammed Shannawaz,Suchitra M Shenoy,Jeevan K. Shetty,Pavanchand Shetty,Kenji Shibuya,Jae Il Shin,Parnian Shobeiri,Migbar Sibhat,Achintya D. Singh,Jasvinder A. Singh,Surjit Singh,Valentin Yurievich Skryabin,Anna Aleksandrovna Skryabina,Amir Ali Sohrabpour,Suhang Song,Seidamir Pasha Tabaeian,Eyayou Girma Tadesse,M. Taheri,Mircea Tampa,Ker-Kan Tan,Ahmad Tavakoli,Abdelghani Tbakhi,Belay Tefera,Arash Tehrani-Banihashemi,Habtamu Molla Tesfaw,Rekha Thapar,A Thavamani,Seyed Abolfazl Tohidast,Daniel N. Tollosa,Maria Elena Tosti,Marcos Roberto Tovani-Palone,Eugenio Traini,Mai T. Tran,Indang Trihandini,Biruk Shalmeno Tusa,Irfan Ullah,Marco Vacante,Sahel Valadan Tahbaz,Pascual R. Valdez,Shoban Babu Varthya,Bay Van Vo,Yasir Waheed,Adisu Birhanu Weldesenbet,Melat Woldemariam,Suowen Xu,Seyed Hossein Yahyazadeh Jabbari,Mehdi Yaseri,Yigizie Yeshaw,Vahit Yiğit,Birhanu Wubale Yirdaw,Naohiro Yonemoto,Chuanhua Yu,Ismaeel Yunusa,Mazyar Zahir,Leila Zaki,Mohammad Zamani,Maryam Zamanian,Mikhail Sergeevich Zastrozhin,Theo Vos,John W. Ward,M. Ashworth Dirac +440 more
TL;DR: The prevalence of chronic HBV infection declined over time, particularly in children younger than 5 years, since the introduction of hepatitis B vaccination, andHBV-related death rates also decreased, but HBV- related death counts increased as a result of population growth, ageing, and cohort effects.
Journal ArticleDOI
The Global Burden of Disease Study at 30 years
TL;DR: The Global Burden of Disease Study (GBD) as mentioned in this paper has been used to provide timely, valid and relevant assessments of critical health outcomes for more than 30 years and has become progressively more granular.
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The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.
TL;DR: This is the first in a planned series of 10 volumes that will attempt to "summarize epidemiological knowledge about all major conditions and most risk factors" and use historical trends in main determinants to project mortality and disease burden forward to 2020.
Journal Article
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 (vol 380, pg 2197, 2012)
TL;DR: In this article, a comprehensive update of disease burden worldwide incorporating a systematic reassessment of disease and injury-specific epidemiology has been done since the 1990 study, and the authors aimed to calculate disease burden globally and for 21 regions for 1990, 2005, and 2010 with methods to enable meaningful comparisons over time.
Journal ArticleDOI
Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010.
Harvey Whiteford,Harvey Whiteford,Louisa Degenhardt,Louisa Degenhardt,Juergen Rehm,Juergen Rehm,Amanda J Baxter,Amanda J Baxter,Alize J. Ferrari,Alize J. Ferrari,Holly E. Erskine,Holly E. Erskine,Fiona J Charlson,Fiona J Charlson,Rosana E. Norman,Rosana E. Norman,Abraham D. Flaxman,Nicole E. Johns,Roy Burstein,Christopher J L Murray,Theo Vos +20 more
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) as discussed by the authors was used to estimate the burden of disease attributable to mental and substance use disorders in terms of disability-adjusted life years (DALYs), years of life lost to premature mortality (YLLs), and years lived with disability (YLDs).
Journal ArticleDOI
Worldwide Epidemiology of Atrial Fibrillation: A Global Burden of Disease 2010 Study
Sumeet S. Chugh,Rasmus Havmoeller,Kumar Narayanan,David Singh,Michiel Rienstra,Emelia J. Benjamin,Richard F. Gillum,Younghoon Kim,John H. McAnulty,Zhi Jie Zheng,Mohammad H. Forouzanfar,Mohsen Naghavi,George A. Mensah,Majid Ezzati,Christopher J L Murray +14 more
TL;DR: Evidence of progressive increases in overall burden, incidence, prevalence, and AF-associated mortality between 1990 and 2010 is provided, with significant public health implications.
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