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Open AccessJournal ArticleDOI

Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)

TLDR
It remains to be clarified whether the probable or possible therapeutic effects of tDCS are clinically meaningful and how to optimally perform tDCS in a therapeutic setting.
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This article is published in Clinical Neurophysiology.The article was published on 2017-01-01 and is currently open access. It has received 1062 citations till now. The article focuses on the topics: Transcranial direct-current stimulation & Dorsolateral prefrontal cortex.

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Posted ContentDOI

Convolutional neural network MRI segmentation for fast and robust optimization of transcranial electrical current stimulation of the human brain

TL;DR: Results indicate that StarNEt matches FreeSurfer performance on the trained tasks while reducing computation time from several hours to a few seconds, and with the potential to evolve into an effective technique even when patients present large brain abnormalities.
Posted ContentDOI

Prospects for transcranial temporal interference stimulation in humans: a computational study

TL;DR: The results suggest that tTIS is capable of producing more focal fields and allows for better steerability, while field strengths from tACS were slightly higher, and it was possible to steer the peak tT IS field by manipulating the relative strength of the two input fields.
Journal ArticleDOI

Control of cortical oscillatory frequency by a closed-loop system.

TL;DR: A closed-loop system able to control the frequency of slow oscillations (SO) spontaneously generated by the cortical network in vitro that guarantees artifact removal, minimal gaps in data acquisition and robustness in spite of slice heterogeneity is presented.
Journal ArticleDOI

Transcranial Direct Current Stimulation (tDCS) as a Useful Rehabilitation Strategy to Improve Cognition in Patients With Alzheimer's Disease and Parkinson's Disease: An Updated Systematic Review of Randomized Controlled Trials

TL;DR: In this article , a systematic review aimed at evaluating the effects of transcranial direct current stimulation (tDCS) on cognition in people suffering from Alzheimer's disease and Parkinson's disease was conducted.
Journal ArticleDOI

Predictive models for response to non-invasive brain stimulation in stroke: A critical review of opportunities and pitfalls

TL;DR: In this paper, the authors discuss current approaches studying non-invasive brain stimulation in stroke and challenges associated with the development of predictive models of responsiveness to NBSs, and discuss crucial requirements for valid predictive modeling in particular the presence of sufficiently large sample sizes.
References
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Journal ArticleDOI

Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation.

TL;DR: Transcranial electrical stimulation using weak current may be a promising tool to modulate cerebral excitability in a non‐invasive, painless, reversible, selective and focal way.
Journal ArticleDOI

Neuroinflammation in Alzheimer's disease

Michael T. Heneka, +41 more
- 01 Apr 2015 - 
TL;DR: Genome-wide analysis suggests that several genes that increase the risk for sporadic Alzheimer's disease encode factors that regulate glial clearance of misfolded proteins and the inflammatory reaction.
Journal ArticleDOI

Publication bias in clinical research

TL;DR: The presence of publication bias in a cohort of clinical research studies is confirmed and it is suggested that conclusions based only on a review of published data should be interpreted cautiously, especially for observational studies.
Book

Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex

TL;DR: The development of stimulus selectivity in the primary sensory cortex of higher vertebrates is considered in a general mathematical framework and a synaptic evolution scheme of a new kind is proposed in which incoming patterns rather than converging afferents compete.
Journal ArticleDOI

Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex

TL;DR: An integrated model of drug addiction that encompasses intoxication, bingeing, withdrawal, and craving is proposed, and results imply that addiction connotes cortically regulated cognitive and emotional processes, which result in the overvaluing of drug reinforcers, the undervalued of alternative rein forcers, and deficits in inhibitory control for drug responses.
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