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Open AccessJournal ArticleDOI

Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)

TLDR
It remains to be clarified whether the probable or possible therapeutic effects of tDCS are clinically meaningful and how to optimally perform tDCS in a therapeutic setting.
About
This article is published in Clinical Neurophysiology.The article was published on 2017-01-01 and is currently open access. It has received 1062 citations till now. The article focuses on the topics: Transcranial direct-current stimulation & Dorsolateral prefrontal cortex.

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Citations
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Methods and strategies of tDCS for the treatment of pain: current status and future directions.

TL;DR: Conventional tDCS approaches demonstrated promising effects to manage pain and new strategies are under development to enhance tDCS effects and make this approach more easily available by using, for instance, home-based devices.
Journal ArticleDOI

Brain Modulation by Electric Currents in Fibromyalgia: A Structured Review on Non-invasive Approach With Transcranial Electrical Stimulation.

TL;DR: The great majority of reports, based on direct currents (transcranial direct currents stimulation: tDCS) and targeting M1, showed efficacy on pain measures and less on cognitive and affective symptoms, even if several aspects as maintenance of therapeutical effects and optimal stimulation parameters remain to be established.
Journal ArticleDOI

Literature Review on the Effects of tDCS Coupled with Robotic Therapy in Post Stroke Upper Limb Rehabilitation.

TL;DR: The literature analysis seems to demonstrate that the association of tDCS with robotic training has the same clinical gain derived from robotic therapy alone, so future studies should investigate combined approach tailored to the individual patient's characteristics.
References
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Journal ArticleDOI

Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation.

TL;DR: Transcranial electrical stimulation using weak current may be a promising tool to modulate cerebral excitability in a non‐invasive, painless, reversible, selective and focal way.
Journal ArticleDOI

Neuroinflammation in Alzheimer's disease

Michael T. Heneka, +41 more
- 01 Apr 2015 - 
TL;DR: Genome-wide analysis suggests that several genes that increase the risk for sporadic Alzheimer's disease encode factors that regulate glial clearance of misfolded proteins and the inflammatory reaction.
Journal ArticleDOI

Publication bias in clinical research

TL;DR: The presence of publication bias in a cohort of clinical research studies is confirmed and it is suggested that conclusions based only on a review of published data should be interpreted cautiously, especially for observational studies.
Book

Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex

TL;DR: The development of stimulus selectivity in the primary sensory cortex of higher vertebrates is considered in a general mathematical framework and a synaptic evolution scheme of a new kind is proposed in which incoming patterns rather than converging afferents compete.
Journal ArticleDOI

Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex

TL;DR: An integrated model of drug addiction that encompasses intoxication, bingeing, withdrawal, and craving is proposed, and results imply that addiction connotes cortically regulated cognitive and emotional processes, which result in the overvaluing of drug reinforcers, the undervalued of alternative rein forcers, and deficits in inhibitory control for drug responses.
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