Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)
Jean Pascal Lefaucheur,Andrea Antal,Samar S. Ayache,David H. Benninger,Jerome Brunelin,Filippo Cogiamanian,Maria Cotelli,Dirk De Ridder,Roberta Ferrucci,Berthold Langguth,Paola Marangolo,Veit Mylius,Michael A. Nitsche,Frank Padberg,Ulrich Palm,Emmanuel Poulet,Alberto Priori,Simone Rossi,Martin Schecklmann,Sven Vanneste,Ulf Ziemann,Luis Garcia-Larrea,Walter Paulus +22 more
TLDR
It remains to be clarified whether the probable or possible therapeutic effects of tDCS are clinically meaningful and how to optimally perform tDCS in a therapeutic setting.About:
This article is published in Clinical Neurophysiology.The article was published on 2017-01-01 and is currently open access. It has received 1062 citations till now. The article focuses on the topics: Transcranial direct-current stimulation & Dorsolateral prefrontal cortex.read more
Citations
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Transcranial direct current stimulation reduces seizure frequency in patients with refractory focal epilepsy: A randomized, double-blind, sham-controlled, and three-arm parallel multicenter study
Dongju Yang,Qun Wang,Cuiping Xu,Fang Fang,Jingjing Fan,Liping Li,Qiaoyi Du,Ruihua Zhang,Ye Wang,Yicong Lin,Zhaoyang Huang,Hongmei Wang,Chunhong Chen,Qinlan Xu,Yue Wang,Yi Zhang,Zhang Zhang,Xin Zhao,Xuan Zhao,Ting Li,Chunyan Liu,Yulian Niu,Qihui Zhou,Qilin Zhou,Yiran Duan,Xiao Liu,Tingting Yu,Qing Xue,Jing Li,Xiaona Dai,Jiaqi Han,Changhong Ren,Huini Xu,Na Li,Jishui Zhang,Na Xu,Kun Yang,Yuping Wang +37 more
TL;DR: Fourteen consecutive days tDCS significantly decreased SFs in patients with refractory focal epilepsy, with 2 × 20-min daily stimulation protocol being superior to 20-mindaily stimulation protocol.
Journal ArticleDOI
Methods and strategies of tDCS for the treatment of pain: current status and future directions.
Kevin Pacheco-Barrios,Alejandra Cardenas-Rojas,Aurore Thibaut,Aurore Thibaut,Beatriz Teixeira Costa,Isadora Santos Ferreira,Wolnei Caumo,Felipe Fregni +7 more
TL;DR: Conventional tDCS approaches demonstrated promising effects to manage pain and new strategies are under development to enhance tDCS effects and make this approach more easily available by using, for instance, home-based devices.
Journal ArticleDOI
Neuromodulation directed at the prefrontal cortex of subjects with obesity reduces snack food intake and hunger in a randomized trial.
Sascha Heinitz,Martin Reinhardt,Paolo Piaggi,Christopher M. Weise,Enrique Diaz,Emma J. Stinson,Colleen A. Venti,Susanne B. Votruba,Eric M. Wassermann,Miguel Alonso-Alonso,Jonathan Krakoff,Marci E. Gluck +11 more
TL;DR: Short-term anodal tDCS of the left DLPFC did not have an immediate effect on ad libitum food intake or thereby weight change, relative to sham tDCS.
Journal ArticleDOI
Brain Modulation by Electric Currents in Fibromyalgia: A Structured Review on Non-invasive Approach With Transcranial Electrical Stimulation.
Filippo Brighina,Massimiliano Curatolo,Giuseppe Cosentino,Marina de Tommaso,Giuseppe Battaglia,Piercarlo Sarzi-Puttini,Giuliana Guggino,Brigida Fierro +7 more
TL;DR: The great majority of reports, based on direct currents (transcranial direct currents stimulation: tDCS) and targeting M1, showed efficacy on pain measures and less on cognitive and affective symptoms, even if several aspects as maintenance of therapeutical effects and optimal stimulation parameters remain to be established.
Journal ArticleDOI
Literature Review on the Effects of tDCS Coupled with Robotic Therapy in Post Stroke Upper Limb Rehabilitation.
Davide Simonetti,Loredana Zollo,Stefano Milighetti,Sandra Miccinilli,Marco Bravi,Federico Ranieri,Giovanni Magrone,Eugenio Guglielmelli,Vincenzo Di Lazzaro,Silvia Sterzi +9 more
TL;DR: The literature analysis seems to demonstrate that the association of tDCS with robotic training has the same clinical gain derived from robotic therapy alone, so future studies should investigate combined approach tailored to the individual patient's characteristics.
References
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Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation.
Michael A. Nitsche,Walter Paulus +1 more
TL;DR: Transcranial electrical stimulation using weak current may be a promising tool to modulate cerebral excitability in a non‐invasive, painless, reversible, selective and focal way.
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Neuroinflammation in Alzheimer's disease
Michael T. Heneka,Monica J. Carson,Joseph El Khoury,Gary E. Landreth,Frederic Brosseron,Douglas L. Feinstein,Andreas H. Jacobs,Tony Wyss-Coray,Tony Wyss-Coray,Javier Vitorica,Richard M. Ransohoff,Karl Herrup,Sally A. Frautschy,Bente Finsen,Guy C. Brown,Alexei Verkhratsky,Alexei Verkhratsky,Alexei Verkhratsky,Koji Yamanaka,Jari Koistinaho,Eicke Latz,Eicke Latz,Annett Halle,Gabor C. Petzold,Terrence Town,Dave Morgan,Mari L. Shinohara,V. Hugh Perry,Clive Holmes,Clive Holmes,Nicolas G. Bazan,David J. Brooks,Stéphane Hunot,Bertrand Joseph,Nikolaus Deigendesch,Olga Garaschuk,Erik Boddeke,Charles A. Dinarello,John C.S. Breitner,Greg M. Cole,Douglas T. Golenbock,Markus P. Kummer +41 more
TL;DR: Genome-wide analysis suggests that several genes that increase the risk for sporadic Alzheimer's disease encode factors that regulate glial clearance of misfolded proteins and the inflammatory reaction.
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Publication bias in clinical research
TL;DR: The presence of publication bias in a cohort of clinical research studies is confirmed and it is suggested that conclusions based only on a review of published data should be interpreted cautiously, especially for observational studies.
Book
Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex
TL;DR: The development of stimulus selectivity in the primary sensory cortex of higher vertebrates is considered in a general mathematical framework and a synaptic evolution scheme of a new kind is proposed in which incoming patterns rather than converging afferents compete.
Journal ArticleDOI
Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex
Rita Z. Goldstein,Nora D. Volkow +1 more
TL;DR: An integrated model of drug addiction that encompasses intoxication, bingeing, withdrawal, and craving is proposed, and results imply that addiction connotes cortically regulated cognitive and emotional processes, which result in the overvaluing of drug reinforcers, the undervalued of alternative rein forcers, and deficits in inhibitory control for drug responses.
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