Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)
Jean Pascal Lefaucheur,Andrea Antal,Samar S. Ayache,David H. Benninger,Jerome Brunelin,Filippo Cogiamanian,Maria Cotelli,Dirk De Ridder,Roberta Ferrucci,Berthold Langguth,Paola Marangolo,Veit Mylius,Michael A. Nitsche,Frank Padberg,Ulrich Palm,Emmanuel Poulet,Alberto Priori,Simone Rossi,Martin Schecklmann,Sven Vanneste,Ulf Ziemann,Luis Garcia-Larrea,Walter Paulus +22 more
TLDR
It remains to be clarified whether the probable or possible therapeutic effects of tDCS are clinically meaningful and how to optimally perform tDCS in a therapeutic setting.About:
This article is published in Clinical Neurophysiology.The article was published on 2017-01-01 and is currently open access. It has received 1062 citations till now. The article focuses on the topics: Transcranial direct-current stimulation & Dorsolateral prefrontal cortex.read more
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Walking in multiple sclerosis improves with tDCS: a randomized, double-blind, sham-controlled study.
Giuseppina Pilloni,Claire Choi,Michael Shaw,Giancarlo Coghe,Lauren B. Krupp,Marilyn Moffat,Eleonora Cocco,Massimiliano Pau,Leigh Charvet +8 more
TL;DR: To evaluate whether multiple sessions of transcranial direct current stimulation applied to the primary motor (M1) cortex paired with aerobic exercise can improve walking functions in multiple sclerosis (MS), data are presented on subjects with a history of multiple sclerosis.
Journal ArticleDOI
Anodal transcranial direct current stimulation over left inferior frontal gyrus enhances sentence comprehension
TL;DR: In this article, anodal tDCS over the left inferior frontal gyrus (LIFG) was used to enhance natural language comprehension in a sentence-to-picture matching task.
Journal ArticleDOI
Polarity-specific modulation of pain processing by transcranial direct current stimulation – a blinded longitudinal fMRI study
Steffen Naegel,Josephine Biermann,Nina Theysohn,Christoph Kleinschnitz,Hans-Christoph Diener,Zaza Katsarava,Mark Obermann,Dagny Holle +7 more
TL;DR: This study demonstrates polarity-specific modulation of cerebral pain processing, in reconfirmation of previous electrophysiological data, and contributes to a network-based understanding of tDCS’s impact on cerebral pain-processing.
Journal ArticleDOI
Effectiveness of anodal transcranial direct current stimulation to improve muscle strength and motor functionality after incomplete spinal cord injury: a systematic review and meta-analysis.
Amanda Vitória Lacerda de Araújo,Felipe Piccarone Gonçalves Ribeiro,Thais Massetti,Kelsey A. Potter-Baker,Mar Cortes,Ela B. Plow,Talita Dias da Silva,James Tonks,Renato Anghinah,Fernando Henrique Magalhães,Felipe Fregni,Carlos Bandeira de Mello Monteiro +11 more
TL;DR: Overall, there was a significant effect of tDCS in improving motor functionality following iSCI, however, a small ES and the marginal p-value suggest that these results should be interpreted with caution.
Journal ArticleDOI
Long-lasting increase in axonal excitability after epidurally applied DC.
TL;DR: The results show that combining epidural stimulation and transspinal DC polarization may dramatically improve their outcome and result in more effective pain control and the return of impaired motor functions.
References
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Journal ArticleDOI
Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation.
Michael A. Nitsche,Walter Paulus +1 more
TL;DR: Transcranial electrical stimulation using weak current may be a promising tool to modulate cerebral excitability in a non‐invasive, painless, reversible, selective and focal way.
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Neuroinflammation in Alzheimer's disease
Michael T. Heneka,Monica J. Carson,Joseph El Khoury,Gary E. Landreth,Frederic Brosseron,Douglas L. Feinstein,Andreas H. Jacobs,Tony Wyss-Coray,Tony Wyss-Coray,Javier Vitorica,Richard M. Ransohoff,Karl Herrup,Sally A. Frautschy,Bente Finsen,Guy C. Brown,Alexei Verkhratsky,Alexei Verkhratsky,Alexei Verkhratsky,Koji Yamanaka,Jari Koistinaho,Eicke Latz,Eicke Latz,Annett Halle,Gabor C. Petzold,Terrence Town,Dave Morgan,Mari L. Shinohara,V. Hugh Perry,Clive Holmes,Clive Holmes,Nicolas G. Bazan,David J. Brooks,Stéphane Hunot,Bertrand Joseph,Nikolaus Deigendesch,Olga Garaschuk,Erik Boddeke,Charles A. Dinarello,John C.S. Breitner,Greg M. Cole,Douglas T. Golenbock,Markus P. Kummer +41 more
TL;DR: Genome-wide analysis suggests that several genes that increase the risk for sporadic Alzheimer's disease encode factors that regulate glial clearance of misfolded proteins and the inflammatory reaction.
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Publication bias in clinical research
TL;DR: The presence of publication bias in a cohort of clinical research studies is confirmed and it is suggested that conclusions based only on a review of published data should be interpreted cautiously, especially for observational studies.
Book
Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex
TL;DR: The development of stimulus selectivity in the primary sensory cortex of higher vertebrates is considered in a general mathematical framework and a synaptic evolution scheme of a new kind is proposed in which incoming patterns rather than converging afferents compete.
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Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex
Rita Z. Goldstein,Nora D. Volkow +1 more
TL;DR: An integrated model of drug addiction that encompasses intoxication, bingeing, withdrawal, and craving is proposed, and results imply that addiction connotes cortically regulated cognitive and emotional processes, which result in the overvaluing of drug reinforcers, the undervalued of alternative rein forcers, and deficits in inhibitory control for drug responses.
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