Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)
Jean Pascal Lefaucheur,Andrea Antal,Samar S. Ayache,David H. Benninger,Jerome Brunelin,Filippo Cogiamanian,Maria Cotelli,Dirk De Ridder,Roberta Ferrucci,Berthold Langguth,Paola Marangolo,Veit Mylius,Michael A. Nitsche,Frank Padberg,Ulrich Palm,Emmanuel Poulet,Alberto Priori,Simone Rossi,Martin Schecklmann,Sven Vanneste,Ulf Ziemann,Luis Garcia-Larrea,Walter Paulus +22 more
TLDR
It remains to be clarified whether the probable or possible therapeutic effects of tDCS are clinically meaningful and how to optimally perform tDCS in a therapeutic setting.About:
This article is published in Clinical Neurophysiology.The article was published on 2017-01-01 and is currently open access. It has received 1062 citations till now. The article focuses on the topics: Transcranial direct-current stimulation & Dorsolateral prefrontal cortex.read more
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Efficacy and safety of transcranial direct current stimulation as an add-on treatment for obsessive-compulsive disorder: a randomized, sham-controlled trial.
Renata de Melo Felipe da Silva,Andre R. Brunoni,Stephan Goerigk,Marcelo C. Batistuzzo,Daniel L. C. Costa,Juliana Belo Diniz,Frank Padberg,Giordano D’Urso,Euripedes Constantino Miguel,Roseli G. Shavitt +9 more
TL;DR: The results suggest that cathodal tDCS over the SMA is an effective add-on strategy in treatment-resistant OCD.
Journal ArticleDOI
A systematic review and meta-analysis of transcranial direct-current stimulation effects on cognitive function in patients with Alzheimer’s disease
TL;DR: Improved memory and general cognitive function in patients with AD was shown in this meta-analysis, and due to the small number of studies and the high heterogeneity of the data, more high-quality studies using standardized parameters and measures are needed before tDCS can be considered as a treatment for AD.
Journal ArticleDOI
Electroencephalography and Functional Magnetic Resonance Imaging-Guided Simultaneous Transcranial Direct Current Stimulation and Repetitive Transcranial Magnetic Stimulation in a Patient With Minimally Conscious State.
Yicong Lin,Tiaotiao Liu,Qian Huang,Yingying Su,Weibi Chen,Daiquan Gao,Xin Tian,Taicheng Huang,Zonglei Zhen,Tao Han,Hong Ye,Yuping Wang +11 more
TL;DR: The application of EEG and fMRI to characterize the functional connectivity features of the network in an MCS patient provided a reasonable and accurate stimulation target and verified the changes in functional connectivity resulting from stimulation.
Journal ArticleDOI
The Effects of Transcranial Direct Current Stimulation on Balance and Gait in Stroke Patients: A Systematic Review and Meta-Analysis.
TL;DR: In this article, the authors explored the short-term effects of transcranial direct current stimulation (tDCS) on improving balance function and gait in stroke patients, and showed that active tDCS has beneficial effects on timed up and go test (TUGT) [mean difference (MD): 0.35; 95% confidence interval (CI):0.11 to 0.58] and functional ambulation category (FAC) (MD: -2.93; 95 percent CI: -3.93 to -1.15) in stroke patient.
Journal ArticleDOI
Effects of Transcranial Direct Current Stimulation for Treatment of Primary Dysmenorrhea: Preliminary Results of a Randomized Sham-Controlled Trial.
Rodrigo Pegado,Luana Karyne Silva,Hégila da Silva Dantas,Hialison Andrade Câmara,Karime Andrade Mescouto,Edson Silva-Filho,Johnnatas Mikael Lopes,Maria Thereza Albuquerque Barbosa Cabral Micussi,Grasiéla Nascimento Correia +8 more
TL;DR: The intervention provided significant improvements on NRS in active tDCS, and some preliminary evidence for the potential role of tDCS as a contributor to the management of symptoms of PDM is provided.
References
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Journal ArticleDOI
Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation.
Michael A. Nitsche,Walter Paulus +1 more
TL;DR: Transcranial electrical stimulation using weak current may be a promising tool to modulate cerebral excitability in a non‐invasive, painless, reversible, selective and focal way.
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Neuroinflammation in Alzheimer's disease
Michael T. Heneka,Monica J. Carson,Joseph El Khoury,Gary E. Landreth,Frederic Brosseron,Douglas L. Feinstein,Andreas H. Jacobs,Tony Wyss-Coray,Tony Wyss-Coray,Javier Vitorica,Richard M. Ransohoff,Karl Herrup,Sally A. Frautschy,Bente Finsen,Guy C. Brown,Alexei Verkhratsky,Alexei Verkhratsky,Alexei Verkhratsky,Koji Yamanaka,Jari Koistinaho,Eicke Latz,Eicke Latz,Annett Halle,Gabor C. Petzold,Terrence Town,Dave Morgan,Mari L. Shinohara,V. Hugh Perry,Clive Holmes,Clive Holmes,Nicolas G. Bazan,David J. Brooks,Stéphane Hunot,Bertrand Joseph,Nikolaus Deigendesch,Olga Garaschuk,Erik Boddeke,Charles A. Dinarello,John C.S. Breitner,Greg M. Cole,Douglas T. Golenbock,Markus P. Kummer +41 more
TL;DR: Genome-wide analysis suggests that several genes that increase the risk for sporadic Alzheimer's disease encode factors that regulate glial clearance of misfolded proteins and the inflammatory reaction.
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Publication bias in clinical research
TL;DR: The presence of publication bias in a cohort of clinical research studies is confirmed and it is suggested that conclusions based only on a review of published data should be interpreted cautiously, especially for observational studies.
Book
Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex
TL;DR: The development of stimulus selectivity in the primary sensory cortex of higher vertebrates is considered in a general mathematical framework and a synaptic evolution scheme of a new kind is proposed in which incoming patterns rather than converging afferents compete.
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Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex
Rita Z. Goldstein,Nora D. Volkow +1 more
TL;DR: An integrated model of drug addiction that encompasses intoxication, bingeing, withdrawal, and craving is proposed, and results imply that addiction connotes cortically regulated cognitive and emotional processes, which result in the overvaluing of drug reinforcers, the undervalued of alternative rein forcers, and deficits in inhibitory control for drug responses.
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Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)
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