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Open AccessJournal ArticleDOI

Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)

TLDR
It remains to be clarified whether the probable or possible therapeutic effects of tDCS are clinically meaningful and how to optimally perform tDCS in a therapeutic setting.
About
This article is published in Clinical Neurophysiology.The article was published on 2017-01-01 and is currently open access. It has received 1062 citations till now. The article focuses on the topics: Transcranial direct-current stimulation & Dorsolateral prefrontal cortex.

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Citations
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Journal ArticleDOI

REAC Neuromodulation Treatments in Depression, Anxiety and Stress. A Comparative Retrospective Study.

TL;DR: In this paper, the effects of two different modalities of administration of the neuro psycho physical optimization (NPPO) neuromodulation treatment, applied with radio electric asymmetric conveyer (REAC) devices, were compared.
Journal ArticleDOI

Paired Acute Invasive/Non-invasive Stimulation (PAINS) study: A phase I/II randomized, sham-controlled crossover trial in chronic neuropathic pain.

TL;DR: In this article, the authors employed a randomized, sham-controlled crossover study design to investigate whether single-session tDCS would have an additive therapeutic effect alongside DRG stimulation (DRGS) in the treatment of chronic pain.
Journal ArticleDOI

The effect of high-definition transcranial direct current stimulation on pain processing in a healthy population: A single-blinded crossover controlled study

TL;DR: In this article , the effects of high-definition anodic stimulation of primary motor cortex (M1) and DLPFC on conditioned pain modulation (CPM) and pain thresholds were investigated.
Journal ArticleDOI

Activation of ephrinb1/EPHB2/MAP-2/NMDAR Mediates Hippocampal Neurogenesis Promoted by Transcranial Direct Current Stimulation in Cerebral-Ischemic Mice.

TL;DR: In this paper, the authors investigated the effect and mechanism of repetitive anodal-tDCS on hippocampal neurogenesis after cerebral ischemia in mice and found that the effect was related to the activation of the ephrinb1/EPHB2/MAP-2/NMDAR signaling pathway.
Book ChapterDOI

Personalization of Multi-electrode Setups in tCS/tES: Methods and Advantages

TL;DR: A pipeline that leverages individualized head models combined with montage optimization algorithms to reduce the variability of the E-field distributions over subjects in tCS is described.
References
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Journal ArticleDOI

Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation.

TL;DR: Transcranial electrical stimulation using weak current may be a promising tool to modulate cerebral excitability in a non‐invasive, painless, reversible, selective and focal way.
Journal ArticleDOI

Neuroinflammation in Alzheimer's disease

Michael T. Heneka, +41 more
- 01 Apr 2015 - 
TL;DR: Genome-wide analysis suggests that several genes that increase the risk for sporadic Alzheimer's disease encode factors that regulate glial clearance of misfolded proteins and the inflammatory reaction.
Journal ArticleDOI

Publication bias in clinical research

TL;DR: The presence of publication bias in a cohort of clinical research studies is confirmed and it is suggested that conclusions based only on a review of published data should be interpreted cautiously, especially for observational studies.
Book

Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex

TL;DR: The development of stimulus selectivity in the primary sensory cortex of higher vertebrates is considered in a general mathematical framework and a synaptic evolution scheme of a new kind is proposed in which incoming patterns rather than converging afferents compete.
Journal ArticleDOI

Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex

TL;DR: An integrated model of drug addiction that encompasses intoxication, bingeing, withdrawal, and craving is proposed, and results imply that addiction connotes cortically regulated cognitive and emotional processes, which result in the overvaluing of drug reinforcers, the undervalued of alternative rein forcers, and deficits in inhibitory control for drug responses.
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