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Koji Yamanaka

Researcher at Nagoya University

Publications -  111
Citations -  18199

Koji Yamanaka is an academic researcher from Nagoya University. The author has contributed to research in topics: Amyotrophic lateral sclerosis & SOD1. The author has an hindex of 42, co-authored 93 publications receiving 15572 citations. Previous affiliations of Koji Yamanaka include RIKEN Brain Science Institute & University of California, San Diego.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Neuroinflammation in Alzheimer's disease

Michael T. Heneka, +41 more
- 01 Apr 2015 - 
TL;DR: Genome-wide analysis suggests that several genes that increase the risk for sporadic Alzheimer's disease encode factors that regulate glial clearance of misfolded proteins and the inflammatory reaction.
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Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia

Séverine Boillée, +7 more
- 02 Jun 2006 - 
TL;DR: Onset and progression of amyotrophic lateral sclerosis represent distinct disease phases defined by mutant action within different cell types to generate non–cell-autonomous killing of motor neurons; these findings validate therapies, including cell replacement, targeted to the non-neuronal cells.
Journal ArticleDOI

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.

Koji Yamanaka, +8 more
- 01 Mar 2008 - 
TL;DR: These findings demonstrate that mutant astrocytes are viable targets for therapies for slowing the progression of non–cell autonomous killing of motor neurons in ALS.
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Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

Kazuhiro Iwai, +7 more
- 26 Oct 1999 - 
TL;DR: The results suggest that pVHL might be the substrate recognition subunit of the VBC-CUL-2 E3 ligase, the first example of a human tumor-suppressor protein being directly involved in the ubiquitin conjugation system which leads to the targeted degradation of substrate proteins.