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Open AccessJournal ArticleDOI

Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)

TLDR
It remains to be clarified whether the probable or possible therapeutic effects of tDCS are clinically meaningful and how to optimally perform tDCS in a therapeutic setting.
About
This article is published in Clinical Neurophysiology.The article was published on 2017-01-01 and is currently open access. It has received 1062 citations till now. The article focuses on the topics: Transcranial direct-current stimulation & Dorsolateral prefrontal cortex.

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Citations
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Journal ArticleDOI

Neurostimulation for drug-resistant epilepsy: a systematic review of clinical evidence for efficacy, safety, contraindications and predictors for response.

TL;DR: Head-to-head comparison of treatment modalities such as VNS, DBS and RNS across different epileptic syndromes are required to decide which treatment modality is the most effective for a given patient scenario.
Journal ArticleDOI

Non-invasive brain stimulation for fine motor improvement after stroke: a meta-analysis.

TL;DR: The results show that NIBS is associated with gains in fine motor performance in chronic stroke patients and healthy subjects, which supports the effects of NIBS on motor learning and encourages investigation to optimize their effects in clinical and research settings.
Journal ArticleDOI

Changing Brain Networks Through Non-invasive Neuromodulation.

TL;DR: Evidence in a clinical setting is presented to support the idea that non-invasive neuromodulation modulates brain networks, rather than just the local stimulation target, using neurmodulation studies in tinnitus and major depression as examples.
References
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Journal ArticleDOI

Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation.

TL;DR: Transcranial electrical stimulation using weak current may be a promising tool to modulate cerebral excitability in a non‐invasive, painless, reversible, selective and focal way.
Journal ArticleDOI

Neuroinflammation in Alzheimer's disease

Michael T. Heneka, +41 more
- 01 Apr 2015 - 
TL;DR: Genome-wide analysis suggests that several genes that increase the risk for sporadic Alzheimer's disease encode factors that regulate glial clearance of misfolded proteins and the inflammatory reaction.
Journal ArticleDOI

Publication bias in clinical research

TL;DR: The presence of publication bias in a cohort of clinical research studies is confirmed and it is suggested that conclusions based only on a review of published data should be interpreted cautiously, especially for observational studies.
Book

Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex

TL;DR: The development of stimulus selectivity in the primary sensory cortex of higher vertebrates is considered in a general mathematical framework and a synaptic evolution scheme of a new kind is proposed in which incoming patterns rather than converging afferents compete.
Journal ArticleDOI

Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex

TL;DR: An integrated model of drug addiction that encompasses intoxication, bingeing, withdrawal, and craving is proposed, and results imply that addiction connotes cortically regulated cognitive and emotional processes, which result in the overvaluing of drug reinforcers, the undervalued of alternative rein forcers, and deficits in inhibitory control for drug responses.
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