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Journal ArticleDOI

Guidelines for the Management of Rheumatoid Arthritis 2002 Update

TLDR
The guideline reviewed in this month's column describes the recommended care of patients who have been previously diagnosed with RA.
Abstract
Rheumatoid arthritis (RA) is a progressive polyarthritis that is responsible for over nine million office visits annually. It is likely that most nurse practitioners will care for one or more patients with RA because approximately 1% of the adult population is affected by this disabling disorder. The guideline reviewed in this month's column describes the recommended care of patients who have been previously diagnosed with RA.

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The Management of Chronic Pain in Important Patient Subgroups

TL;DR: The use of mild opioids, such as codeine and tramadol, and strong opioids,such as morphine, hydromorphone and oxycodone, may be appropriate where paracetamol and other non-opioid analgesics are ineffective in chronic non-cancer pain.
Journal ArticleDOI

Correlation of CX3CL1 and CX3CR1 levels with response to infliximab therapy in patients with rheumatoid arthritis.

TL;DR: The results suggest that the CX3CL1-CX3CR1 system in patients with active RA may be sensitive to anti-tumor necrosis factor-α therapy, and confirm that CX 3CL1 plays a crucial role in the pathogenesis of RA.
Journal ArticleDOI

Patients with stable long-standing rheumatoid arthritis continue to deteriorate despite intensified treatment with traditional disease modifying anti-rheumatic drugs--results of the British Rheumatoid Outcome Study Group randomized controlled clinical trial.

TL;DR: The trial showed no additional benefit of intensified treatment with traditional disease modifying anti-rheumatic drugs (DMARDs) in patients with stable, established RA and it proved hard to suppress C-reactive protein levels.
Journal ArticleDOI

Influence of Methotrexate Dose on Its Efficacy and Safety in Rheumatoid Arthritis Patients: Evidence Based on the Variety of Prescribing Approaches Among Practicing Japanese Rheumatologists in a Single Institute-Based Large Observational Cohort (IORRA)

TL;DR: This study demonstrated that extensive methotrexate use effectively suppressed RA disease activity and inhibits disability progression and found that it is critical to pay attention to patient-reported adverse reactions.
References
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Journal ArticleDOI

Measurement of patient outcome in arthritis.

TL;DR: A structure for representation of patient outcome is presented, together with a method for outcome measurement and validation of the technique in rheumatoid arthritis, and these techniques appear extremely useful for evaluation of long term outcome of patients with rheumatic diseases.
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