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Open AccessJournal Article

Photoacoustic imaging in biomedicine

Xu Xiao
- 01 Jan 2008 - 
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.
Abstract
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.

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Citations
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Biomedical photoacoustic imaging

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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
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Tutorial on Photoacoustic Microscopy and Computed Tomography

TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
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Development and Applications of Photo-triggered Theranostic Agents

TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
References
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Selective detection of cancer using spectroscopic photoacoustic imaging and bioconjugated gold nanoparticles

TL;DR: The results of this study indicate that photoacoustic imaging is capable of highly sensitive and selective detection of cancer cells by utilizing the plasmon resonance coupling effect of EGFR targeted gold nanoparticles.
Proceedings ArticleDOI

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TL;DR: In this article, a microwave-induced thermoacoustic detection system for embedded targets in lossy media is presented, which achieves reliable detection of 5 cm × 5 cm/2 cm targets embedded in a large Agarose sample at a 20 cm acoustic standoff.
Proceedings ArticleDOI

Free-hand 3d optoacoustic imaging of vasculature

TL;DR: In this article, a stereo-camera is used to track the transducer position for fast and convenient acquisition of 3D optoacoustic data for 3D b-scans.
Journal ArticleDOI

Computational analysis of the effectiveness of blood flushing with saline injection from an intravascular diagnostic catheter.

TL;DR: A computational fluid dynamics model is reported that allows for the optimization of blood flushing parameters in a manner that minimizes the amount of saline needed to clear the optical field of view and reduces any adverse effects caused by the external saline jet.
Proceedings ArticleDOI

High resolution optoacoustic detection of nanoparticles on living cells

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