scispace - formally typeset
Open AccessJournal Article

Photoacoustic imaging in biomedicine

Xu Xiao
- 01 Jan 2008 - 
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.
Abstract
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.

read more

Citations
More filters
Proceedings ArticleDOI

Image reconstruction in photoacoustic tomography using integrating detectors accounting for frequency-dependent attenuation

TL;DR: In this article, the authors proposed integrating detectors that integrate the pressure in one or two dimensions -a line or a plane detector, respectively, to measure the optical contrast of a sample with high spatial resolution.
Proceedings ArticleDOI

Fine-resolution photoacoustic imaging of the eye

TL;DR: In this article, a focused 20 MHz ultrasound probe with a central aperture was used for imaging the eye, which can produce 1-μJ, 5-nsec pulses at 532 or 1064 nm with a 20-μm spot size at a 500 Hz repetition rate.
Journal ArticleDOI

Spread Spectrum Photoacoustic Tomography With Image Optimization

TL;DR: This work came up with a method including signal recovery based on inverse filtering and multi-sampled signal de-noising, with which it was capable of rebuilding wider band PA signals and reconstructing PA images with higher SNR.
Journal ArticleDOI

Sharp estimates for the Neumann functions and applications to quantitative photo-acoustic imaging in inhomogeneous media ∗

TL;DR: In this article, the authors obtained sharp Lp and Holder estimates for the Neumann function of the operator ∇⋅γ∇−ik on a bounded domain and also obtained quantitative description of its singularity.
Proceedings ArticleDOI

Drug delivery monitoring by photoacoustic tomography with an ICG encapsulated double emulsion

TL;DR: In this article, the authors successfully encapsulated ICG in an ultrasound-triggerable perfluorocarbon double emulsion that prevents ICG from binding with plasma proteins, which could facilitate spatial and quantitative monitoring of ultrasound initiated drug delivery.
References
More filters
Journal ArticleDOI

Biomedical photoacoustic imaging

TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
Journal ArticleDOI

Multiscale photoacoustic microscopy and computed tomography.

TL;DR: PAT holds the promise of in vivo imaging at multiple length scales ranging from subcellular organelles to organs with the same contrast origin, an important application in multiscale systems biology research.
Journal ArticleDOI

Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
Journal ArticleDOI

Tutorial on Photoacoustic Microscopy and Computed Tomography

TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
Journal ArticleDOI

Development and Applications of Photo-triggered Theranostic Agents

TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
Related Papers (5)