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Open AccessJournal Article

Photoacoustic imaging in biomedicine

Xu Xiao
- 01 Jan 2008 - 
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.
Abstract
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.

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Citations
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Biomedical photoacoustic imaging

TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
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Multiscale photoacoustic microscopy and computed tomography.

TL;DR: PAT holds the promise of in vivo imaging at multiple length scales ranging from subcellular organelles to organs with the same contrast origin, an important application in multiscale systems biology research.
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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
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Tutorial on Photoacoustic Microscopy and Computed Tomography

TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
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Development and Applications of Photo-triggered Theranostic Agents

TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
References
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Using Some Nanoparticles as Contrast Agents for Optical Bioimaging

TL;DR: In this paper, gold nanorods (GNRs), quantum dots (QDs), and organically modified silica (ORMOSIL) nanoparticles can overcome many drawbacks of conventional agents such as poor contrast, photobleaching, and low chemical and optical stability in biological environment.
Proceedings ArticleDOI

Feasibility of transcranial photoacoustic imaging for interventional guidance of endonasal surgeries

TL;DR: To investigate feasibility, a plastisol phantom embedded with a spherical metal target was submerged in a water tank and results are generally promising for photoacoustic-guided endonasal surgeries.
Proceedings ArticleDOI

Multimodal simultaneous photoacoustic tomography, optical resolution microscopy, and OCT system

TL;DR: In this paper, a combination of photo-acoustic tomography (PAT), optical resolution photoacoustic microscopy (ORPAM) and optical coherence tomography instrument was developed for imaging biological tissues.
Proceedings ArticleDOI

Quantitative Photoacoustic Blood Oxygenation Imaging Using Deep Residual And Recurrent Neural Network

TL;DR: A deep residual, and recurrent neural network, i.e., DR2U-net, is developed for the quantitative estimation of blood oxygenation of photoacoustic imaging that can extract fluence distribution information from optical absorption images only using two wavelengths of light in Monte Carlo simulation.
Journal ArticleDOI

Comparative Effects of Linearly and Circularly Polarized Illumination on Microwave-Induced Thermoacoustic Tomography

TL;DR: In this paper, a customized horn antenna and a helical antenna working at 3 GHz were used to provide linearly polarized and circularly polarized illuminations, respectively, for TAT images.
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