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Open AccessJournal Article

Photoacoustic imaging in biomedicine

Xu Xiao
- 01 Jan 2008 - 
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.
Abstract
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.

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Citations
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Biomedical photoacoustic imaging

TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
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Multiscale photoacoustic microscopy and computed tomography.

TL;DR: PAT holds the promise of in vivo imaging at multiple length scales ranging from subcellular organelles to organs with the same contrast origin, an important application in multiscale systems biology research.
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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
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Tutorial on Photoacoustic Microscopy and Computed Tomography

TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
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Development and Applications of Photo-triggered Theranostic Agents

TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
References
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Proceedings ArticleDOI

Theoretical and experimental investigation of multispectral photoacoustic osteoporosis detection method

TL;DR: In this article, the effects of multiple wavelength excitations and induced osteoporosis on the PA signal were investigated and a simple two mode theoretical model was fitted to the measured phase signals.
Proceedings ArticleDOI

A microfabricated water-immersible scanning mirror with a small form factor for handheld ultrasound and photoacoustic microscopy

TL;DR: In this paper, a micro-fabricated water-immersible scanning mirror with a small form factor was developed for in-vivo high-speed and wide-field ultrasound and photoacoustic microscopy.
Proceedings ArticleDOI

The use of optically activated nanoparticles to enhance controlled lesion formation from high intensity focused ultrasound exposures

TL;DR: In this article, it has been shown that heating nanoparticles with a laser whilst they are simultaneously under tension from a high intensity focused ultrasound (HIFU) field results in a significant reduction in the optical fluence and acoustic pressure thresholds required for bubble formation.

Investigation of Techniques to increase the Field of View of a Staring Transducer Array for Photoacoustic Imaging

Avery Raess
TL;DR: In this article, the authors present a co-authorship statement, acknowledgements, and a Table of Table of Contents for Co-Authorship Statement and acknowledgements of authors.

Three-Dimensional Photoacoustic Computed Tomography: Imaging Models and Reconstruction Algorithms

Kun Wang
TL;DR: Wang et al. as discussed by the authors proposed a three-dimensional photoacoustic computed tomography (PACT) imaging model that incorporates the characteristics of data acquisition systems and applied it to experimental data.
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