Open AccessJournal Article
Photoacoustic imaging in biomedicine
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.Abstract:
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.read more
Citations
More filters
Journal ArticleDOI
Biomedical photoacoustic imaging
TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
Journal ArticleDOI
Multiscale photoacoustic microscopy and computed tomography.
TL;DR: PAT holds the promise of in vivo imaging at multiple length scales ranging from subcellular organelles to organs with the same contrast origin, an important application in multiscale systems biology research.
Journal ArticleDOI
Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents
Jonathan F. Lovell,Cheng S. Jin,Cheng S. Jin,Elizabeth Huynh,Elizabeth Huynh,Honglin Jin,Honglin Jin,Chulhong Kim,John L. Rubinstein,Warren C. W. Chan,Weiguo Cao,Lihong V. Wang,Gang Zheng,Gang Zheng +13 more
TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
Journal ArticleDOI
Tutorial on Photoacoustic Microscopy and Computed Tomography
TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
Journal ArticleDOI
Development and Applications of Photo-triggered Theranostic Agents
Prakash Rai,Srivalleesha Mallidi,Xiang Zheng,Ramtin Rahmanzadeh,Youssef Mir,Stefan A. Elrington,Ahmat Khurshid,Ahmat Khurshid,Tayyaba Hasan,Tayyaba Hasan +9 more
TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
References
More filters
Journal ArticleDOI
Multi-source quantitative photoacoustic tomography with detector response function and limited-view scanning
Feng Jing,Zhou Weifeng,Gao Hao +2 more
TL;DR: A direct image reconstruction method is proposed that incorporates SIR, EIR and limited-view scanning in a coupled opto-acoustic forward model, regularizes the nonlinear QPAT data fidelity with tensor framelet sparsity, and then solves theQPAT problem with Quasi-Newton method based alternating direction method of multipliers.
Dissertation
Minimally interactive segmentation with application to human placenta in fetal MR images
TL;DR: Experimental results show that the proposed algorithms outperform traditional interactive segmentation methods in terms of accuracy and interactivity, and might be suitable for segmentation of the placenta in planning systems for fetal and maternal surgery, and for rapid characterization of theplacenta by MR images.
Journal ArticleDOI
A frequency‐domain non‐contact photoacoustic microscope based on an adaptive interferometer
TL;DR: A frequency-domain, non-contact approach to photoacoustic microscopy (PAM) that employs amplitude-modulated (0.1-1 MHz) laser for excitation (638-nm pump) in conjunction with a 2-wave mixing interferometer (532-nm probe) for non- contact detection of photoac acoustic waves at the specimen surface is presented.
Proceedings ArticleDOI
Aortic atherosclerotic plaque detection using a multiwavelength handheld photoacoustic imaging system
TL;DR: A handheld photoacoustic imaging device developed can evaluate plaque properties by analysis with the photoac acoustic spectrum and verified its usefulness in phantom experiments with a bovine aorta in which mimic plaque had been embedded.
Proceedings ArticleDOI
Enhancement of photoacoustic signal using a novel light illumination improvement device: In vivo feasibility animal study
TL;DR: In this article, a light illumination improvement device, called light catcher, was proposed to increase the effective excitation energy, resulting in an increased photoacoustic (PA) signal for the same light source without increasing power.
Related Papers (5)
New Progress of Photoacoustic Imaging Technology in Biomedical Applications
Sihua Yang,Da Xing +1 more