Open AccessJournal Article
Photoacoustic imaging in biomedicine
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.Abstract:
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.read more
Citations
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Biomedical photoacoustic imaging
TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
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Multiscale photoacoustic microscopy and computed tomography.
TL;DR: PAT holds the promise of in vivo imaging at multiple length scales ranging from subcellular organelles to organs with the same contrast origin, an important application in multiscale systems biology research.
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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents
Jonathan F. Lovell,Cheng S. Jin,Cheng S. Jin,Elizabeth Huynh,Elizabeth Huynh,Honglin Jin,Honglin Jin,Chulhong Kim,John L. Rubinstein,Warren C. W. Chan,Weiguo Cao,Lihong V. Wang,Gang Zheng,Gang Zheng +13 more
TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
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Tutorial on Photoacoustic Microscopy and Computed Tomography
TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
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Development and Applications of Photo-triggered Theranostic Agents
Prakash Rai,Srivalleesha Mallidi,Xiang Zheng,Ramtin Rahmanzadeh,Youssef Mir,Stefan A. Elrington,Ahmat Khurshid,Ahmat Khurshid,Tayyaba Hasan,Tayyaba Hasan +9 more
TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
References
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Journal ArticleDOI
Silver Nanoplate Contrast Agents for in Vivo Molecular Photoacoustic Imaging
Kimberly A. Homan,Michael L Souza,Ryan L. Truby,Geoffrey P. Luke,Christopher Green,Erika C. Vreeland,Stanislav Emelianov +6 more
TL;DR: The synthesized silver nanoplates are well suited for a host of biomedical imaging and sensing applications and shown to be nontoxic at concentrations up to 1 mg/mL.
Journal ArticleDOI
Photoacoustic Source Detection and Reflection Artifact Removal Enabled by Deep Learning
TL;DR: It is shown that the CNN-based information can be displayed in a novel artifact-free image format, enabling us to effectively remove reflection artifacts from photoacoustic images, which is not possible with traditional geometry-based beamforming.
Proceedings ArticleDOI
The challenges for quantitative photoacoustic imaging
TL;DR: In this paper, the authors describe the principal challenges that must be overcome for such a general procedure to be successful, and describe an inversion procedure that is not specific to any particular situation and free of restrictive suppositions.
Journal ArticleDOI
An Imaging Model Incorporating Ultrasonic Transducer Properties for Three-Dimensional Optoacoustic Tomography
Kun Wang,Sergey A. Ermilov,Richard Su,Hans-Peter Brecht,Alexander A. Oraevsky,Mark A. Anastasio +5 more
TL;DR: It is demonstrated that use of the imaging model in an iterative reconstruction method can improve the spatial resolution of the optoacoustic images as compared to those reconstructed assuming point-like ultrasound transducers.
Journal ArticleDOI
Albumin-NIR dye self-assembled nanoparticles for photoacoustic pH imaging and pH-responsive photothermal therapy effective for large tumors.
TL;DR: Using HSA-Croc as a pH-responsive photothermal agent, effective photothermal ablation of large tumors is realized, likely owing to the more evenly distributed intratumoral heating compared to that achieved by conventional pH-insensitive photothermal agents, which are effective mostly for tumors with small sizes.
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