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Open AccessJournal Article

Photoacoustic imaging in biomedicine

Xu Xiao
- 01 Jan 2008 - 
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.
Abstract
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.

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Citations
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Biomedical photoacoustic imaging

TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
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Multiscale photoacoustic microscopy and computed tomography.

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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
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Tutorial on Photoacoustic Microscopy and Computed Tomography

TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
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Development and Applications of Photo-triggered Theranostic Agents

TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
References
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Proceedings ArticleDOI

Optical spectroscopic ultrasound displacement imaging

TL;DR: A novel imaging method, named optical spectroscopic ultrasound displacement (OSUD) imaging, is proposed, which enables optical Spectroscopic imaging in deep scattering tissue using multiple low-cost continuous-wave laser sources and ultrasound imaging equipment.
Proceedings ArticleDOI

Ultrasound array photoacoustic microscopy for dynamic in vivo 3D imaging

TL;DR: The demonstrated capability suggests that high-speed 3-D photoacoustic imaging should facilitate the understanding of the dynamics of various dyes in SLNs, and potentially help identify SLNs with high accuracy.

Acoustic Inverse Scattering for Breast Cancer Microcalcification Detection

TL;DR: In this article, the linear sampling method was augmented with a method for estimating the inhomogeneous Green's function for wave propagation in the breast, which can be translated to an acoustic imaging system to detect, localize, and characterize microcalcifications in breast phantoms using data from the far-field scattering measurements.
Journal Article

Ultrasound-transmission parameter imaging in a photoacoustic imager

TL;DR: In this article, a hybrid imaging system was proposed to image both optical absorption properties and acoustic transmission properties of an object in a two-dimensional slice using a computed tomography photoacoustic imager.
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