Open AccessJournal Article
Photoacoustic imaging in biomedicine
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.Abstract:
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.read more
Citations
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Measurement of Broadband Temperature-Dependent Ultrasonic Attenuation and Dispersion Using Photoacoustics
TL;DR: A photoacoustic technique for the transmission measurement of temperature-dependent ultrasonic attenuation and dispersion is described, which is demonstrated through temperature- dependent ultrasound measurements in castor oil and olive oil.
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Multispectral Optoacoustic Tomography—Volumetric Color Hearing in Real Time
TL;DR: The technical essentials of MSOT are provided, including latest developments in the inverse theory, spectral processing algorithms, and imaging instrumentation, and a separate section is devoted to the state of the art of molecular imaging applications using MSOT.
Proceedings ArticleDOI
Photoacoustic imaging of mesenchymal stem cells in living mice via silica-coated gold nanorods
TL;DR: Silica-coated gold nanorods are used as photoacoustic contrast agents and deployed to image and quantitate mesenchymal stem cells during implant into the muscle tissue of live mice and the photoac acoustic signal was validated with histology a long-term fluorescent tracking dye after MSC transplant.
Journal ArticleDOI
Target detection and quantification using a hybrid hand-held diffuse optical tomography and photoacoustic tomography system.
Patrick D. Kumavor,Chen Xu,Andres Aguirre,John Gamelin,Yasaman Ardeshirpour,Behnoosh Tavakoli,Saeid Zanganeh,Umar Alqasemi,Yi Yang,Quing Zhu +9 more
TL;DR: It is shown that the relative optical absorption map provided by photoacoustic tomography can potentially guide the diffuse optical tomography to accurately reconstruct target absorption maps.
Journal ArticleDOI
Reflected light intensity profile of two-layer tissues: phantom experiments
TL;DR: It is reported, for the first time, an experimental observation of a typical reflected light intensity behavior for the two-layer structure characterized by two different slopes in the reflected light profile of the irradiated tissue.
References
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Biomedical photoacoustic imaging
TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
Journal ArticleDOI
Multiscale photoacoustic microscopy and computed tomography.
TL;DR: PAT holds the promise of in vivo imaging at multiple length scales ranging from subcellular organelles to organs with the same contrast origin, an important application in multiscale systems biology research.
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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents
Jonathan F. Lovell,Cheng S. Jin,Cheng S. Jin,Elizabeth Huynh,Elizabeth Huynh,Honglin Jin,Honglin Jin,Chulhong Kim,John L. Rubinstein,Warren C. W. Chan,Weiguo Cao,Lihong V. Wang,Gang Zheng,Gang Zheng +13 more
TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
Journal ArticleDOI
Tutorial on Photoacoustic Microscopy and Computed Tomography
TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
Journal ArticleDOI
Development and Applications of Photo-triggered Theranostic Agents
Prakash Rai,Srivalleesha Mallidi,Xiang Zheng,Ramtin Rahmanzadeh,Youssef Mir,Stefan A. Elrington,Ahmat Khurshid,Ahmat Khurshid,Tayyaba Hasan,Tayyaba Hasan +9 more
TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
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