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Development and Applications of Photo-triggered Theranostic Agents

TLDR
Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2010-08-30 and is currently open access. It has received 457 citations till now.

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Silver Nanoparticles: Synthesis, Characterization, Properties, Applications, and Therapeutic Approaches

TL;DR: This review extensively discusses the multifunctional bio-applications of AgNPs; for example, as antibacterial, antifungal, antiviral,Anti-inflammatory, anti-angiogenic, and anti-cancer agents, and the mechanism of the anti- cancer activity of Ag NPs.
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New photosensitizers for photodynamic therapy

TL;DR: The dual-specificity of PDT relies on accumulation of the PS in diseased tissue and also on localized light delivery, and future directions include photochemical internalization, genetically encoded protein PSs, theranostics, two-photon absorption PDT, and sonodynamic therapy using ultrasound.
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Diverse Applications of Nanomedicine

Beatriz Pelaz, +91 more
- 14 Mar 2017 - 
TL;DR: An overview of recent developments in nanomedicine is provided and the current challenges and upcoming opportunities for the field are highlighted and translation to the clinic is highlighted.
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Mesoporous Silica-Coated Gold Nanorods as a Light-Mediated Multifunctional Theranostic Platform for Cancer Treatment

TL;DR: With doxorubicin hydrochloride loaded, Au@SiO(2)-DOX show two light-mediated therapeutic modes: low power density laser-triggered drug release for chemotherapy, and high powerdensity laser-induced hyperthermia, which suggest the potential for in-vivo applications.
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Oncologic photodynamic therapy: Basic principles, current clinical status and future directions

TL;DR: An overview of the clinical trials conducted over the last 10 years is provided, illustrating how PDT is applied in the clinic today, and the factors that hamper the exploration of this effective therapy and what should be changed to render it a more effective and more widely available option for patients.
References
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Journal ArticleDOI

Atherosclerosis — An Inflammatory Disease

TL;DR: Atherosclerosis is an inflammatory disease as discussed by the authors, and it is a major cause of death in the United States, Europe, and much of Asia, despite changes in lifestyle and use of new pharmacologic approaches to lower plasma cholesterol concentrations.
Journal Article

Atherosclerosis is an Inflammatory Disease

TL;DR: Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations, cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.
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Cancer Statistics, 2009

TL;DR: The most recent data on cancer incidence, mortality, and survival from the American Cancer Society (ACS) is presented in this paper, where the authors compare the three major cancer sites in men (lung, prostate, and colon and rectum [colorectum]) and in two major cancers sites in women (breast and colorectal) over a 15-year period.
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Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics

TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
Journal ArticleDOI

The Ki‐67 protein: From the known and the unknown

TL;DR: Although the Ki‐67 protein is well characterized on the molecular level and extensively used as a proliferation marker, the functional significance still remains unclear; there are indications, however, that Ki‐ 67 protein expression is an absolute requirement for progression through the cell‐division cycle.
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