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Open AccessJournal Article

Photoacoustic imaging in biomedicine

Xu Xiao
- 01 Jan 2008 - 
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.
Abstract
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.

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Citations
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Design and Demonstration of a Configurable Imaging Platform for Combined Laser, Ultrasound, and Elasticity Imaging

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An Improved Filtered Back-Projection Algorithm for Photoacoustic Tomography

TL;DR: In this paper, the anisotropic diffusion (AD) is introduced to improve the reconstruction algorithm of the filtered back-projection (FBP) algorithm for photoacoustic tomography (PAT).
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Ultrasound and photoacoustic imaging for enhanced image-guided endovenous laser ablation procedures

TL;DR: The utility of US and PA in tracking fiber tip in a set of vessel-mimicking phantoms indicated artifact-free and accurate detection of the fiber tip using PA in contrast to US, and the utility of PA for real-time monitoring of temperature increase during laser ablation procedures was demonstrated.
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Quantification of effective attenuation coefficients using continuous wavelet transform of photoacoustic signals

TL;DR: A computational simulation reveals that the time-resolved frequency spectra exhibit better correlation with the coefficients than do power spectra calculated using a Fourier transformation.
References
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Journal ArticleDOI

Biomedical photoacoustic imaging

TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
Journal ArticleDOI

Multiscale photoacoustic microscopy and computed tomography.

TL;DR: PAT holds the promise of in vivo imaging at multiple length scales ranging from subcellular organelles to organs with the same contrast origin, an important application in multiscale systems biology research.
Journal ArticleDOI

Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
Journal ArticleDOI

Tutorial on Photoacoustic Microscopy and Computed Tomography

TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
Journal ArticleDOI

Development and Applications of Photo-triggered Theranostic Agents

TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
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