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Open AccessJournal Article

Photoacoustic imaging in biomedicine

Xu Xiao
- 01 Jan 2008 - 
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.
Abstract
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.

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Citations
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Biomedical photoacoustic imaging

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Multiscale photoacoustic microscopy and computed tomography.

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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
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Tutorial on Photoacoustic Microscopy and Computed Tomography

TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
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Development and Applications of Photo-triggered Theranostic Agents

TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
References
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Journal ArticleDOI

Real-time photoacoustic and ultrasound dual-modality imaging system facilitated with graphics processing unit and code parallel optimization

TL;DR: A fully integrated PAT and US dual-modality imaging system, which performs signal scanning, image reconstruction, and display for both photoacoustic (PA) and US imaging all in a truly real-time manner, is reported.
Journal ArticleDOI

Three-dimensional photoacoustic imaging using fiber-based line detectors.

TL;DR: Three-dimensional images of phantoms and insects using a glass-fiber-based Fabry-Perot interferometer as integrating line detector are presented.
Journal ArticleDOI

CuS-Based Theranostic Micelles for NIR-Controlled Combination Chemotherapy and Photothermal Therapy and Photoacoustic Imaging

TL;DR: In both two-dimensional monolayer cell and three-dimensional multicellular tumor spheroid models, GE11-tagged CuS-based micelles under NIR irradiation, enabling the combination chemotherapy and PTT, exhibited the best therapeutic outcome due to a synergistic effect.
Journal ArticleDOI

Croconaine nanoparticles with enhanced tumor accumulation for multimodality cancer theranostics

TL;DR: The CR780-PEG5K not only displayed the strength of small molecules, but also demonstrated the advantages of nanomaterials as a versatile theranostic agent.
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