Open AccessJournal Article
Photoacoustic imaging in biomedicine
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.Abstract:
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.read more
Citations
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A Miniature Capacitive Micromachined Ultrasonic Transducer Array for Minimally Invasive Photoacoustic Imaging
TL;DR: In this paper, a capacitive micromachined ultrasonic transducer (CMUT) array for minimally invasive photoacoustic imaging (PAI) is presented.
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Photoacoustic tomography of the mouse cerebral cortex with a high-numerical-aperture-based virtual point detector.
Changhui Li,Lihong V. Wang +1 more
TL;DR: A virtual point detector based on a high numerical aperture (NA), positively focused transducer was used that has a wide omnidirectional acceptance angle, a high sensitivity, and a negligible aperture effect.
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Low-Cost Photoacoustic Tomography System Based on Multi-Channel Delay-Line Module
TL;DR: A multiway PA signal delay-line module for PAT was proposed, which merges four channels of PA signals in one channel that significantly reduces DAQ’s channel number needed for PAT system.
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Quantitative photoacoustic tomography using illuminations from a single direction.
TL;DR: The results show that the spatially modulated illumination patterns from a single direction could be used to provide multiple illuminations for quantitative photoacoustic tomography and can beused to distinguish absorption and scattering inclusions located near the surface of the target.
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Frequency domain reconstruction for photo- and thermoacoustic tomography with line detectors
TL;DR: In this article, a line-shaped detector was used for the recording of acoustic data, and the three-dimensional image reconstruction problem was reduced to a series of two-dimensional ones.
References
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Journal ArticleDOI
Biomedical photoacoustic imaging
TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
Journal ArticleDOI
Multiscale photoacoustic microscopy and computed tomography.
TL;DR: PAT holds the promise of in vivo imaging at multiple length scales ranging from subcellular organelles to organs with the same contrast origin, an important application in multiscale systems biology research.
Journal ArticleDOI
Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents
Jonathan F. Lovell,Cheng S. Jin,Cheng S. Jin,Elizabeth Huynh,Elizabeth Huynh,Honglin Jin,Honglin Jin,Chulhong Kim,John L. Rubinstein,Warren C. W. Chan,Weiguo Cao,Lihong V. Wang,Gang Zheng,Gang Zheng +13 more
TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
Journal ArticleDOI
Tutorial on Photoacoustic Microscopy and Computed Tomography
TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
Journal ArticleDOI
Development and Applications of Photo-triggered Theranostic Agents
Prakash Rai,Srivalleesha Mallidi,Xiang Zheng,Ramtin Rahmanzadeh,Youssef Mir,Stefan A. Elrington,Ahmat Khurshid,Ahmat Khurshid,Tayyaba Hasan,Tayyaba Hasan +9 more
TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
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