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Open AccessJournal Article

Photoacoustic imaging in biomedicine

Xu Xiao
- 01 Jan 2008 - 
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.
Abstract
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.

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Citations
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Biomedical photoacoustic imaging

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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
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Tutorial on Photoacoustic Microscopy and Computed Tomography

TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
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Development and Applications of Photo-triggered Theranostic Agents

TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
References
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Journal ArticleDOI

A simple Fourier transform-based reconstruction formula for photoacoustic computed tomography with a circular or spherical measurement geometry

TL;DR: A hybrid reconstruction formula is derived that is mathematically exact and operates on a data function that is expressed in the temporal frequency and spatial domains of PACT and yields a straightforward numerical implementation that is robust and two orders of magnitude more computationally efficient than filtered backprojection algorithms.
Journal ArticleDOI

Lifetime-based photoacoustic oxygen sensing in vivo

TL;DR: A lifetime-based photoacoustic technique for the measurement of oxygen in vivo, using an oxygen sensitive dye, enabling real time quantification of blood oxygenation, is demonstrated for the first time.
Journal ArticleDOI

Quantitative Analysis of Caspase-1 Activity in Living Cells Through Dynamic Equilibrium of Chlorophyll-Based Nano-assembly Modulated Photoacoustic Signals

TL;DR: A biocompatible self-assembly from chlorophyll-peptide derivatives is presented and first correlate the dynamic equilibrium with ratiometric photoacoustic signals and the activity of caspase-1 enables reflection of the bacterial infection in the early stage.
Journal ArticleDOI

Photoacoustic lifetime imaging for direct in vivo tissue oxygen monitoring.

TL;DR: Two studies which apply photoacoustic lifetime imaging (PALI) to monitor changes of tissue oxygen induced by external modulations are presented and it is demonstrated that PALI is able to reflect the change in oxygen level with respect to normal, oxygen-rich, and oxygen-poor breathing conditions.
Journal ArticleDOI

Information theoretic regularization in diffuse optical tomography

TL;DR: In this article, the authors examined the possibility of regularizing diffuse optical tomography via the introduction of a priori information from alternative high-resolution anatomical modalities, using the information theory concepts of mutual information (MI) and joint entropy (JE).
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