Open AccessJournal Article
Photoacoustic imaging in biomedicine
TLDR
In this paper, the authors provide an overview of the rapidly developing field of photoacoustic imaging, which is a promising method for visualizing biological tissues with optical absorbers, compared with optical imaging and ultrasonic imaging.Abstract:
Photoacoustic imaging is a promising method for visualizing biological tissues with optical absorbers. This article provides an overview of the rapidly developing field of photoacoustic imaging. Photoacoustics, the physical basis of photoacoustic imaging, is analyzed briefly. The merits of photoacoustic technology, compared with optical imaging and ultrasonic imaging, are described. Various imaging techniques are also discussed, including scanning tomography, computed tomography and original detection of photoacoustic imaging. Finally, some biomedical applications of photoacoustic imaging are summarized.read more
Citations
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Biomedical photoacoustic imaging
TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
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Multiscale photoacoustic microscopy and computed tomography.
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Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents
Jonathan F. Lovell,Cheng S. Jin,Cheng S. Jin,Elizabeth Huynh,Elizabeth Huynh,Honglin Jin,Honglin Jin,Chulhong Kim,John L. Rubinstein,Warren C. W. Chan,Weiguo Cao,Lihong V. Wang,Gang Zheng,Gang Zheng +13 more
TL;DR: The development of porphysomes; nanovesicles formed from self-assembled porphyrin bilayers that generated large, tunable extinction coefficients, structure-dependent fluorescence self-quenching and unique photothermal and photoacoustic properties demonstrate the multimodal potential of organic nanoparticles for biophotonic imaging and therapy.
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Tutorial on Photoacoustic Microscopy and Computed Tomography
TL;DR: In this paper, the fundamentals of photoacoustics are first introduced and then, scanning photoacoustic microscopy and reconstruction-based photo-acoustic computed tomography (or photo acoustics computed tomograph) are covered.
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Development and Applications of Photo-triggered Theranostic Agents
Prakash Rai,Srivalleesha Mallidi,Xiang Zheng,Ramtin Rahmanzadeh,Youssef Mir,Stefan A. Elrington,Ahmat Khurshid,Ahmat Khurshid,Tayyaba Hasan,Tayyaba Hasan +9 more
TL;DR: Recent developments in the use of light-triggered theranostic agents for simultaneous imaging and photoactivation of therapeutic agents for several diseases are reviewed.
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Development of a multi-modal tissue diagnostic system combining high frequency ultrasound and photoacoustic imaging with lifetime fluorescence spectroscopy
Yang Sun,Douglas N. Stephens,Jesung Park,Yinghua Sun,Laura Marcu,Jonathan M. Cannata,K.K. Shung +6 more
TL;DR: Current results demonstrate that the fusion of these techniques enables sequentially detection of functional, morphological, and compositional features of biological tissue, suggesting potential applications in diagnosis of tumors and atherosclerotic plaques.
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Gold nanoparticles as cancer theranostic agents
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TL;DR: The role of GNPs in improving radiotherapy efficiency as radiosensitizers is reviewed, with a focus on recent progresses in the field of gold nanostructures in cancer treatment and diagnosis.
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A fast 512-element ring array photoacoustic imaging system for small animals
John Gamelin,Anastasios Maurudis,Andres Aguirre,Fei Huang,Puyun Guo,Lihong V. Wang,Quing Zhu +6 more
TL;DR: A 512-element photoacoustic tomography system for small animal imaging using a ring ultrasound array has been developed in this article, which features a 5 MHz piezocomposite transducer array formed into a complete circular aperture.
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Thermo-Acoustic Ultrasound for Detection of RF-Induced Device Lead Heating in MRI
TL;DR: It is demonstrated that thermo-acoustic ultrasound (TAUS) has the potential to be utilized for a pre-scan procedure assessing the risk of RF-induced lead tip heating in MRI and is a promising method for assessing RF implant safety.
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