Open Access
Supplementary Materials for Host-Derived Nitrate Boosts Growth of E. coli in the Inflamed Gut
Sebastian E. Winter,Maria G. Winter,Mariana N. Xavier,A. Marijke Keestra,Richard Laughlin,Gabriel Gomez,Jing Wu,Ina Popova,Sanjai J. Parikh,L. Garry Adams,Renée M. Tsolis,Andreas J. Bäumler +11 more
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The article was published on 2013-01-01 and is currently open access. It has received 505 citations till now.read more
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Role of the microbiota in cancer growth and necrosis: the challenges and opportunities of bacteriotherapy for cancer and its complications
Wei Pan,Yongbo Kang +1 more
TL;DR: The interacting network of cancer, host, and microbial genotypes is identified in this review to assess how microorganism may play an important role in carcinogenesis, developing novel therapeutic and diagnostic strategies for cancer and its complications.
Journal ArticleDOI
mSphere of Influence: a Controlled Burn-Pathogen Manipulation of the Dynamic Chemistry That Results from Inflammation
TL;DR: This mSphere of Influence article reflects on how gut inflammation provides a respiratory electron acceptor for Salmonella by Winter and colleagues (S. E. Winter, P. Thiennimitr, M. P. Butler, et al., Nature 467:426–429) made an impact on Neal Hammer by demonstrating that Salmoneella enterica serotype Typhimurium metabolism is uniquely suited to exploit the chemical by-products that result from the host’s inflammatory response
Dissertation
Not Got Milk? The Effect on the Gut Microbiome of Removing Dairy from the Diet
TL;DR: This study shows that alterations to a diet can cause changes of the relative abundances of bacteria in the human gut at multiple taxonomic levels, but that at the level of the entire community these shifts in gut microbiota can be reversed.
Dissertation
Identification of Clinical and Bacterial Genetic Risk Factors Associated withKlebsiella pneumoniae Infection
Journal ArticleDOI
Alternations of Gastric Microbiota with Mucosal Atrophy and Intestinal Metaplasia
TL;DR: The Korean Journal of Helicobacter and Upper Gastrointestinal Research is an Open-Access Journal that permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
TL;DR: A simple and highly efficient method to disrupt chromosomal genes in Escherichia coli in which PCR primers provide the homology to the targeted gene(s), which should be widely useful, especially in genome analysis of E. coli and other bacteria.
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A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in Gram negative bacteria
TL;DR: In this paper, a new vector strategy for the insertion of foreign genes into the genomes of gram negative bacteria not closely related to Escherichia coli was developed, which can utilize any gram negative bacterium as a recipient for conjugative DNA transfer.
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Diversity of the human intestinal microbial flora.
Paul B. Eckburg,Elisabeth M. Bik,Charles N. Bernstein,Elizabeth Purdom,Les Dethlefsen,Michael Sargent,Steven R. Gill,Karen E. Nelson,David A. Relman,David A. Relman,David A. Relman +10 more
TL;DR: A majority of the bacterial sequences corresponded to uncultivated species and novel microorganisms, and significant intersubject variability and differences between stool and mucosa community composition were discovered.
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Obesity alters gut microbial ecology
Ruth E. Ley,Fredrik Bäckhed,Peter J. Turnbaugh,Catherine A. Lozupone,Robin D. Knight,Jeffrey I. Gordon +5 more
TL;DR: Analysis of the microbiota of genetically obese ob/ob mice, lean ob/+ and wild-type siblings, and their ob/+ mothers, all fed the same polysaccharide-rich diet, indicates that obesity affects the diversity of the gut microbiota and suggests that intentional manipulation of community structure may be useful for regulating energy balance in obese individuals.
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Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
Daniel N. Frank,Allison L. St. Amand,Robert A. Feldman,Edgar C. Boedeker,Noam Harpaz,Norman R. Pace +5 more
TL;DR: Patient stratification by GI microbiota provides further evidence that CD represents a spectrum of disease states and suggests that treatment of some forms of IBD may be facilitated by redress of the detected microbiological imbalances.