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The NIMH Research Domain Criteria (RDoC) Project: Precision Medicine for Psychiatry
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This article is published in American Journal of Psychiatry.The article was published on 2014-04-01. It has received 1147 citations till now. The article focuses on the topics: MEDLINE & Research Domain Criteria.read more
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Major depressive disorder
Christian Otte,Stefan M. Gold,Stefan M. Gold,Brenda W.J.H. Penninx,Carmine M. Pariante,Amit Etkin,Maurizio Fava,David C. Mohr,Alan F. Schatzberg +8 more
TL;DR: An overview of the current evidence of major depressive disorder, including its epidemiology, aetiology, pathophysiology, diagnosis and treatment, is provided.
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A Gene-Based Association Method for Mapping Traits Using Reference Transcriptome Data
Eric R. Gamazon,Heather E. Wheeler,Kaanan P. Shah,Sahar V. Mozaffari,Keston Aquino-Michaels,Robert J. Carroll,Anne E. Eyler,Joshua C. Denny,Dan L. Nicolae,Nancy J. Cox,Nancy J. Cox,Hae Kyung Im +11 more
TL;DR: The results demonstrate that PrediXcan can detect known and new genes associated with disease traits and provide insights into the mechanism of these associations.
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WHO World Mental Health Surveys International College Student Project: Prevalence and distribution of mental disorders.
Randy P. Auerbach,Philippe Mortier,Ronny Bruffaerts,Jordi Alonso,Corina Benjet,Pim Cuijpers,Koen Demyttenaere,David Daniel Ebert,Jennifer Greif Green,Penelope Hasking,Elaine Murray,Matthew K. Nock,Stephanie Pinder-Amaker,Nancy A. Sampson,Dan J. Stein,Gemma Vilagut,Alan M. Zaslavsky,Ronald C. Kessler +17 more
TL;DR: Initial results from the first stage of the WHO World Mental Health International College Student project are reported, in which a series of surveys in 19 colleges were carried out with the aim of estimating prevalence and basic sociodemographic correlates of common mental disorders among first-year college students.
Journal ArticleDOI
Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
Gin S Malhi,Darryl Bassett,Philip Boyce,Richard A. Bryant,Paul B. Fitzgerald,Kristina Fritz,Malcolm Hopwood,Bill Lyndon,Roger T. Mulder,Greg Murray,Richard J Porter,Ajeet B. Singh +11 more
TL;DR: The Mood Disorder CPG is the first Clinical Practice Guideline to address both depressive and bipolar disorders and provides up-to-date recommendations and guidance within an evidence-based framework, supplemented by expert clinical consensus.
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An Overview of Autism Spectrum Disorder, Heterogeneity and Treatment Options
TL;DR: This review provides a broad overview of the history, prevalence, etiology, clinical presentation, and heterogeneity of ASD and explores the potential of a new wave of research examining objective biomarkers to facilitate the evaluation of sub-typing, diagnosis, and treatment response in ASD.
References
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Research diagnostic criteria: Rationale and reliability.
TL;DR: The development and initial reliability studies of a set of specific diagnostic criteria for a selected group of functional psychiatric disorders, the Research Diagnostic Criteria (RDC), indicate high reliability for diagnostic judgments made using these criteria.
Journal ArticleDOI
Research domain criteria (RDoC): toward a new classification framework for research on mental disorders
Journal ArticleDOI
Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010.
Harvey Whiteford,Harvey Whiteford,Louisa Degenhardt,Louisa Degenhardt,Juergen Rehm,Juergen Rehm,Amanda J Baxter,Amanda J Baxter,Alize J. Ferrari,Alize J. Ferrari,Holly E. Erskine,Holly E. Erskine,Fiona J Charlson,Fiona J Charlson,Rosana E. Norman,Rosana E. Norman,Abraham D. Flaxman,Nicole E. Johns,Roy Burstein,Christopher J L Murray,Theo Vos +20 more
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) as discussed by the authors was used to estimate the burden of disease attributable to mental and substance use disorders in terms of disability-adjusted life years (DALYs), years of life lost to premature mortality (YLLs), and years lived with disability (YLDs).
Journal ArticleDOI
Establishment of Diagnostic Validity in Psychiatric Illness: Its Application to Schizophrenia
Eli Robins,Samuel B. Guze +1 more
TL;DR: It was shown by follow-up and family studies that poor prognosis cases can be validly separated clinically from good prediction cases, and the authors conclude that good prognosis "schizophrenia" is not mild schizophrenia, but a different illness.
Journal ArticleDOI
Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it
TL;DR: Rather than seek biomedical tests that can ‘diagnose’ DSM-defined disorders, the field should focus on identifying biologically homogenous subtypes that cut across phenotypic diagnosis—thereby sidestepping the issue of a gold standard.
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