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Andrea Z. LaCroix
Researcher at Fred Hutchinson Cancer Research Center
Publications - 276
Citations - 27753
Andrea Z. LaCroix is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Women's Health Initiative & Osteoporosis. The author has an hindex of 88, co-authored 273 publications receiving 25538 citations. Previous affiliations of Andrea Z. LaCroix include Group Health Cooperative & University of California, San Diego.
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Journal ArticleDOI
Design of the Women's Health Initiative clinical trial and observational study
Garnet L. Anderson,S. Cummings,L. S. Freedman,C. Furberg,Maureen M. Henderson,Susan R. Johnson,L. Kuller,JoAnn E. Manson,A. Oberman,Ross L. Prentice,Jacques E. Rossouw,L. Finnegan,R. Hiatt,L. Pottern,J. McGowan,C. Clifford,B. Caan,V. Kipnis,B. Ettinger,S. Sidney,G. Bailey,Andrea Z. LaCroix,Anne McTiernan,Deborah J. Bowen,C. Chen,Barbara B. Cochrane,Julie R. Hunt,Alan R. Kristal,Brian J. Lund,Ruth E. Patterson,Jeffrey L. Probstfield,Lesley F. Tinker,Nicole Urban,Ching Yun Wang,Emily White,J. M. Kotchen,S. Shumaker,P. Rautaharju,F. Rautaharju,E. Stein,P. Laskarzewski,P. Steiner,K. Sagar,M. Nevitt,M. Dockrell,T. Fuerst,John H. Himes,M. Stevens,F. Cammarata,S. Lindenfelser,Bruce M. Psaty,D. Siscovick,W. Longstreth,S. Heckbert,S. Wassertheil-Smoller,W. Frishman,Judy Wylie-Rosett,D. Barad,R. Freeman,S. Miller,Jennifer Hays,R. Young,C. Crowley,M. A. DePoe,G. Burke,E. Paskett,L. Wagenknecht,R. Crouse,L. Parsons,T. Kotchen,E. Braunwald,J. Buring,C. Hennekens,J. M. Gaziano,Annlouise R. Assaf,R. C. Carleton,M. Miller,C. Wheeler,A. Hume,M. Pedersen,O. Strickland,M. Huber,V. Porter,Shirley A.A. Beresford,V. Taylor,N. Woods,J. Hsia,V. Barnabei,M. Bovun,Rowan T. Chlebowski,R. Detrano,A. Nelson,J. Heiner,S. Pushkin,B. Valanis,V. Stevens,E. Whitlock,N. Karanja,A. Clark +98 more
TL;DR: The rationale for the interventions being studied in each of the CT components and for the inclusion of the OS component is described, including a brief description of the scientific and logistic complexity of the WHI.
Journal ArticleDOI
Low-Fat Dietary Pattern and Risk of Colorectal Cancer: The Women's Health Initiative Randomized Controlled Dietary Modification Trial
Shirley A.A. Beresford,Karen C. Johnson,Cheryl Ritenbaugh,Norman L. Lasser,Linda Snetselaar,Henry R. Black,Garnet L. Anderson,Annlouise R. Assaf,Annlouise R. Assaf,Tamsen Bassford,Deborah J. Bowen,Robert L. Brunner,Robert G. Brzyski,Bette J. Caan,Rowan T. Chlebowski,Margery Gass,Rosanne C. Harrigan,Jennifer Hays,David Heber,Gerardo Heiss,Susan L. Hendrix,Barbara V. Howard,Judith Hsia,F. Allan Hubbell,Rebecca D. Jackson,Jane Morley Kotchen,Lewis H. Kuller,Andrea Z. LaCroix,Dorothy S. Lane,Robert Langer,Cora E. Lewis,JoAnn E. Manson,Karen L. Margolis,Yasmin Mossavar-Rahmani,Judith K. Ockene,Linda M. Parker,Michael G. Perri,Lawrence S. Phillips,Ross L. Prentice,John A Robbins,Jacques E. Rossouw,Gloria E. Sarto,Marcia L. Stefanick,Linda Van Horn,Mara Z. Vitolins,Jean Wactawski-Wende,Robert B. Wallace,Evelyn P Whitlock +47 more
TL;DR: A low-fat dietary pattern intervention did not reduce the risk of colorectal cancer in postmenopausal women during 8.1 years of follow-up, and secondary analyses suggested potential interactions with baseline aspirin use and combined estrogen-progestin use status.
Journal ArticleDOI
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer
Laufey T. Amundadottir,Peter Kraft,Rachael Z. Stolzenberg-Solomon,Charles S. Fuchs,Gloria M. Petersen,Alan A. Arslan,H. Bas Bueno-de-Mesquita,Myron D. Gross,Kathy J. Helzlsouer,Eric J. Jacobs,Andrea Z. LaCroix,Wei Zheng,Demetrius Albanes,William R. Bamlet,Christine D. Berg,Franco Berrino,Sheila Bingham,Julie E. Buring,Paige M. Bracci,Federico Canzian,Françoise Clavel-Chapelon,Sandra Clipp,Michelle Cotterchio,Mariza de Andrade,Eric J. Duell,John W. Fox,Steven Gallinger,J. Michael Gaziano,J. Michael Gaziano,Edward Giovannucci,Michael Goggins,Carlos A. González,Göran Hallmans,Susan E. Hankinson,Manal Hassan,Elizabeth A. Holly,David J. Hunter,Amy K. Hutchinson,Amy K. Hutchinson,Rebecca D. Jackson,Kevin B. Jacobs,Kevin B. Jacobs,Mazda Jenab,Rudolf Kaaks,Alison P. Klein,Charles Kooperberg,Robert C. Kurtz,Donghui Li,Shannon M. Lynch,Margaret T. Mandelson,Margaret T. Mandelson,Robert R. McWilliams,Julie B. Mendelsohn,Dominique S. Michaud,Dominique S. Michaud,Sara H. Olson,Kim Overvad,Alpa V. Patel,Petra H.M. Peeters,Petra H.M. Peeters,Aleksandar Rajkovic,Elio Riboli,Harvey A. Risch,Xiao-Ou Shu,Gilles Thomas,Geoffrey S. Tobias,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Stephen K. Van Den Eeden,Jarmo Virtamo,Jean Wactawski-Wende,Brian M. Wolpin,Herbert Yu,Kai Yu,Anne Zeleniuch-Jacquotte,Stephen J. Chanock,Patricia Hartge,Robert N. Hoover +77 more
TL;DR: In this paper, a two-stage genome-wide association study of pancreatic cancer, a cancer with one of the lowest survival rates worldwide, was conducted, where 558,542 SNPs were genotyped in 1,896 individuals and 1,939 controls drawn from 12 prospective cohorts plus one hospital-based case-control study.
Journal ArticleDOI
Association between alcohol and cardiovascular disease:Mendelian randomisation analysis based on individual participant data
Michael V. Holmes,Michael V. Holmes,Caroline Dale,Luisa Zuccolo,Richard J. Silverwood,Yiran Guo,Zheng Ye,David Prieto-Merino,Abbas Dehghan,Stella Trompet,Andrew Wong,Alana Cavadino,Dagmar Drogan,Sandosh Padmanabhan,Shanshan Li,Ajay Yesupriya,Maarten Leusink,Johan Sundström,Jaroslav A. Hubacek,Hynek Pikhart,Daniel I. Swerdlow,Andrie G. Panayiotou,S. A. Borinskaya,Chris Finan,Sonia Shah,Karoline Kuchenbaecker,Tina Shah,Jorgen Engmann,Lasse Folkersen,Per Eriksson,Fulvio Ricceri,Olle Melander,Carlotta Sacerdote,Dale M Gamble,Sruti Rayaprolu,Owen A. Ross,Stela McLachlan,OV Vikhireva,Ivonne Sluijs,Robert A. Scott,Vera Adamkova,Leon Flicker,Frank M. van Bockxmeer,Christine Power,Pedro Marques-Vidal,Tom W. Meade,Michael Marmot,José M. Ferro,Sofia Paulos-Pinheiro,Steve E. Humphries,Philippa J. Talmud,Irene Mateo Leach,Niek Verweij,Allan Linneberg,Tea Skaaby,Pieter A. Doevendans,Maarten J Cramer,Pim van der Harst,Olaf H. Klungel,Nicole F. Dowling,Anna F. Dominiczak,Meena Kumari,Andrew N. Nicolaides,Cornelia Weikert,Heiner Boeing,Shah Ebrahim,Tom R. Gaunt,Jackie F. Price,Lars Lannfelt,Anne Peasey,Ruzena Kubinova,Andrzej Pajak,Sofia Malyutina,Mikhail Voevoda,Mikhail Voevoda,Abdonas Tamosiunas,Anke H. Maitland-van der Zee,Paul Norman,Graeme J. Hankey,Graeme J. Hankey,Manuela M. Bergmann,Albert Hofman,Oscar H. Franco,Jackie A. Cooper,Jutta Palmen,Wilko Spiering,Pim A. de Jong,Diana Kuh,Rebecca Hardy,André G. Uitterlinden,M. Arfan Ikram,Ian Ford,Elina Hyppönen,Elina Hyppönen,Osvaldo P. Almeida,Osvaldo P. Almeida,Nicholas J. Wareham,Kay-Tee Khaw,Anders Hamsten,Anders Hamsten,Lise Lotte N. Husemoen,Anne Tjønneland,Janne Schurmann Tolstrup,Eric B. Rimm,Eric B. Rimm,Joline W.J. Beulens,W. M. Monique Verschuren,N. Charlotte Onland-Moret,Marten H. Hofker,S. Goya Wannamethee,Peter H. Whincup,Richard W Morris,Astrid M. Vicente,Hugh Watkins,Hugh Watkins,Martin Farrall,Martin Farrall,J. Wouter Jukema,James F. Meschia,L. Adrienne Cupples,Stephen J. Sharp,Myriam Fornage,Charles Kooperberg,Andrea Z. LaCroix,James Y. Dai,Matthew B. Lanktree,David S. Siscovick,Eric Jorgenson,Bonnie Spring,Josef Coresh,Yun Li,Sarah G. Buxbaum,Pamela J. Schreiner,R. Curtis Ellison,Michael Y. Tsai,Sanjay R. Patel,Sanjay R. Patel,Susan Redline,Andrew D. Johnson,Ron C. Hoogeveen,Hakon Hakonarson,Jerome I. Rotter,Eric Boerwinkle,Paul I.W. de Bakker,Mika Kivimäki,Folkert W. Asselbergs,Folkert W. Asselbergs,Naveed Sattar,Debbie A Lawlor,John C. Whittaker,John C. Whittaker,George Davey Smith,Kenneth J. Mukamal,Bruce M. Psaty,Bruce M. Psaty,James G. Wilson,Leslie A. Lange,Ajna Hamidovic,Aroon D. Hingorani,Børge G. Nordestgaard,Børge G. Nordestgaard,Martin Bobak,David A. Leon,Claudia Langenberg,Tom Palmer,Alexander P. Reiner,Brendan J. Keating,Brendan J. Keating,Frank Dudbridge,Juan P. Casas,Juan P. Casas +170 more
TL;DR: In this article, the causal role of alcohol consumption in cardiovascular disease was investigated using a Mendelian randomisation meta-analysis of 56 epidemiological studies, including 20 259 coronary heart disease cases and 10 164 stroke events.
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer
Laufey T. Amundadottir,Peter Kraft,Rachael Z. Stolzenberg-Solomon,Charles S. Fuchs,Gloria M. Petersen,Alan A. Arslan,H. Bas Bueno-de-Mesquita,Myron D. Gross,Kathy J. Helzlsouer,Eric J. Jacobs,Andrea Z. LaCroix,Wei Zheng,Demetrius Albanes,William R. Bamlet,Christine D. Berg,Franco Berrino,Sheila Bingham,Julie E. Buring,Paige M. Bracci,Federico Canzian,Françoise Clavel-Chapelon,Sandra Clipp,Michelle Cotterchio,Mariza de Andrade,Eric J. Duell,John W. Fox,Steven Gallinger,J. Michael Gaziano,J. Michael Gaziano,Edward Giovannucci,Michael Goggins,Carlos A. González,Göran Hallmans,Susan E. Hankinson,Manal Hassan,Elizabeth A. Holly,David J. Hunter,Amy K. Hutchinson,Amy K. Hutchinson,Rebecca D. Jackson,Kevin B. Jacobs,Kevin B. Jacobs,Mazda Jenab,Rudolf Kaaks,Alison P. Klein,Charles Kooperberg,Robert C. Kurtz,Donghui Li,Shannon M. Lynch,Margaret T. Mandelson,Margaret T. Mandelson,Robert R. McWilliams,Julie B. Mendelsohn,Dominique S. Michaud,Dominique S. Michaud,Sara H. Olson,Kim Overvad,Alpa V. Patel,Petra H.M. Peeters,Petra H.M. Peeters,Aleksandar Rajkovic,Elio Riboli,Harvey A. Risch,Xiao-Ou Shu,Gilles Thomas,Geoffrey S. Tobias,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Stephen K. Van Den Eeden,Jarmo Virtamo,Jean Wactawski-Wende,Brian M. Wolpin,Herbert Yu,Kai Yu,Anne Zeleniuch-Jacquotte,Stephen J. Chanock,Patricia Hartge,Robert N. Hoover +77 more
TL;DR: An association between a locus on 9q34 and pancreatic cancer marked by the SNP rs505922 is identified, consistent with earlier epidemiologic evidence suggesting that people with blood group O may have a lower risk of pancreaticcancer than those with groups A or B.