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Dominique Stoppa-Lyonnet
Researcher at Curie Institute
Publications - 444
Citations - 32995
Dominique Stoppa-Lyonnet is an academic researcher from Curie Institute. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 80, co-authored 420 publications receiving 29316 citations. Previous affiliations of Dominique Stoppa-Lyonnet include PSL Research University & Bosch.
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Journal ArticleDOI
Assessment of human Nter and Cter BRCA1 mutations using growth and localization assays in yeast.
Gaël A. Millot,Gaël A. Millot,Gaël A. Millot,Adeline Berger,Adeline Berger,Adeline Berger,Vincent Lejour,Vincent Lejour,Vincent Lejour,Jean-Baptiste Boulé,Jean-Baptiste Boulé,Jean-Baptiste Boulé,Claude Bobo,Christophe Cullin,Judith Lopes,Judith Lopes,Judith Lopes,Dominique Stoppa-Lyonnet,Dominique Stoppa-Lyonnet,Dominique Stoppa-Lyonnet,Alain Nicolas,Alain Nicolas,Alain Nicolas +22 more
TL;DR: This work designed a new assay, called the “yeast localization phenotype (YLP) assay,” based on the accumulation of BRCA1 in a single inclusion body in the yeast nucleus, which is altered by variants positioned both in the Nter and Cter regions.
Journal ArticleDOI
Reply to prophylactic salpingo‐oophorectomy in a series of 89 women carrying a BRCA1 or a BRCA2 mutation
TL;DR: This study shows that prophylactic SO remains an important option for BRCA1/2 mutation carriers as asymptomatic ovarian/fallopian cancers were found in 4.5% of patients, and longer follow-up and larger series are required to more precisely evaluate the benefits of this procedure in terms of BC incidence, peritoneal malignancy, or recurrence.
Journal ArticleDOI
Non-Coding Variants in BRCA1 and BRCA2 Genes: Potential Impact on Breast and Ovarian Cancer Predisposition.
Elizabeth Santana dos Santos,François Lallemand,Leslie Burke,Dominique Stoppa-Lyonnet,Dominique Stoppa-Lyonnet,Melissa A. Brown,Sandrine M. Caputo,Etienne Rouleau +7 more
TL;DR: This review summarizes the available data on the impact of variants on non-coding regions of BRCA1/2 genes and their role on breast and ovarian cancer predisposition.
Journal ArticleDOI
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
Antoinette Hollestelle,Frederieke H. van der Baan,Andrew Berchuck,Sharon E. Johnatty,Katja K.H. Aben,Bjarni A. Agnarsson,Kristiina Aittomäki,Elisa Alducci,Irene L. Andrulis,Irene L. Andrulis,Hoda Anton-Culver,Natalia Antonenkova,Antonis C. Antoniou,Carmel Apicella,Volker Arndt,Norbert Arnold,Banu Arun,Brita Arver,Alan Ashworth,Laura Baglietto,Laura Baglietto,Laura Baglietto,Rosemary L. Balleine,Elisa V. Bandera,Daniel Barrowdale,Yukie Bean,Lars Beckmann,Matthias W. Beckmann,Javier Benitez,Andreas Berger,Raanan Berger,Benoit Beuselinck,Maria Bisogna,Line Bjørge,Line Bjørge,Carl Blomqvist,Natalia Bogdanova,Anders Bojesen,Stig E. Bojesen,Manjeet K. Bolla,Bernardo Bonanni,Judith S. Brand,Hiltrud Brauch,Hermann Brenner,Louise A. Brinton,Angela Brooks-Wilson,Angela Brooks-Wilson,Fiona Bruinsma,Fiona Bruinsma,Fiona Bruinsma,Joan Brunet,Thomas Brüning,Agnieszka Budzilowska,Clareann H. Bunker,Barbara Burwinkel,Barbara Burwinkel,Ralf Bützow,Saundra S. Buys,Maria A. Caligo,Ian G. Campbell,Ian G. Campbell,Jonathan Carter,Jenny Chang-Claude,Stephen J. Chanock,Kathleen Claes,J. Margriet Collée,Linda S. Cook,Fergus J. Couch,Angela Cox,Daniel W. Cramer,Daniel W. Cramer,Simon S. Cross,Julie M. Cunningham,Cezary Cybulski,Kamila Czene,Francesca Damiola,Agnieszka Dansonka-Mieszkowska,Hatef Darabi,Miguel de la Hoya,Anna deFazio,Anna deFazio,Joe Dennis,Peter Devilee,Ed Dicks,Orland Diez,Jennifer A. Doherty,Susan M. Domchek,Cecilia M. Dorfling,Thilo Dörk,Isabel dos Santos Silva,Andreas du Bois,Martine Dumont,Alison M. Dunning,Mercedes Durán,Douglas F. Easton,Diana Eccles,Robert P. Edwards,Hans Ehrencrona,Bent Ejlertsen,Arif B. Ekici,Steve Ellis,Christoph Engel,Mikael Eriksson,Peter A. Fasching,Lídia Feliubadaló,Jonine D. Figueroa,Dieter Flesch-Janys,Olivia Fletcher,Annette Fontaine,Annette Fontaine,Stefano Fortuzzi,Florentia Fostira,Brooke L. Fridley,Tara M. Friebel,Eitan Friedman,Grace Friel,Debra Frost,Judy Garber,Montserrat Garcia-Closas,Simon A. Gayther,Aleksandra Gentry-Maharaj,Anne-Marie Gerdes,Graham G. Giles,Graham G. Giles,Graham G. Giles,Rosalind Glasspool,Gord Glendon,Andrew K. Godwin,Marc T. Goodman,Martin Gore,Mark H. Greene,Mervi Grip,Jacek Gronwald,Daphne Gschwantler Kaulich,Pascal Guénel,Starr R. Guzman,Lothar Haeberle,Christopher A. Haiman,Per Hall,Sandra L. Halverson,Ute Hamann,Thomas Hansen,Philipp Harter,Jaana M. Hartikainen,Sue Healey,Alexander Hein,Florian Heitz,Brian E. Henderson,Josef Herzog,Michelle A.T. Hildebrandt,Claus Høgdall,Estrid Høgdall,Frans B. L. Hogervorst,John L. Hopper,Keith Humphreys,Tomasz Huzarski,Evgeny N. Imyanitov,Claudine Isaacs,Anna Jakubowska,Ramunas Janavicius,Katarzyna Jaworska,Allan Jensen,Uffe Birk Jensen,Nichola Johnson,Arja Jukkola-Vuorinen,Maria Kabisch,Beth Y. Karlan,Vesa Kataja,Noah D. Kauff,Linda E. Kelemen,Linda E. Kelemen,Michael J. Kerin,Lambertus A. Kiemeney,Susanne K. Kjaer,Julia A. Knight,Julia A. Knight,Jacoba P. Knol-Bout,Irene Konstantopoulou,Veli-Matti Kosma,Camilla Krakstad,Camilla Krakstad,Vessela N. Kristensen,Karoline Kuchenbaecker,Jolanta Kupryjanczyk,Yael Laitman,Diether Lambrechts,Sandrina Lambrechts,Melissa C. Larson,Adriana Lasa,Pierre Laurent-Puig,Conxi Lázaro,Nhu D. Le,Loic Le Marchand,Arto Leminen,Jenny Lester,Douglas A. Levine,Jingmei Li,Dong Liang,Annika Lindblom,Noralane M. Lindor,Jolanta Lissowska,Jirong Long,Karen Lu,Jan Lubinski,Lene Lundvall,Galina Lurie,Phuong L. Mai,Arto Mannermaa,Sara Margolin,Frederique Mariette,Frederik Marmé,John W.M. Martens,Leon F.A.G. Massuger,Christine Maugard,Sylvie Mazoyer,Lesley McGuffog,Valerie McGuire,Catriona McLean,Iain A. McNeish,Alfons Meindl,Florence Menegaux,Primitiva Menéndez,Janusz Menkiszak,Usha Menon,Arjen R. Mensenkamp,Nicola Miller,Roger L. Milne,Roger L. Milne,Francesmary Modugno,Marco Montagna,Kirsten B. Moysich,Heiko Müller,Anna Marie Mulligan,Anna Marie Mulligan,Taru A. Muranen,Steven A. Narod,Katherine L. Nathanson,Roberta B. Ness,Susan L. Neuhausen,Heli Nevanlinna,Patrick Neven,Finn Cilius Nielsen,Sune F. Nielsen,Børge G. Nordestgaard,Robert L. Nussbaum,Kunle Odunsi,Kenneth Offit,Edith Olah,Olufunmilayo I. Olopade,Janet E. Olson,Sara H. Olson,Jan C. Oosterwijk,Irene Orlow,Nick Orr,Sandra Orsulic,Ana Osorio,Laura Ottini,James Paul,Celeste Leigh Pearce,Inge Søkilde Pedersen,Bernard Peissel,Tanja Pejovic,Liisa M. Pelttari,Jo Perkins,Jenny Permuth-Wey,Paolo Peterlongo,Julian Peto,Catherine M. Phelan,Kelly-Anne Phillips,Marion Piedmonte,Malcolm C. Pike,Malcolm C. Pike,Radka Platte,Joanna Plisiecka-Halasa,Elizabeth M. Poole,Elizabeth M. Poole,Bruce Poppe,Katri Pylkäs,Katri Pylkäs,Paolo Radice,Susan J. Ramus,Timothy R. Rebbeck,Malcolm W.R. Reed,Gad Rennert,Harvey A. Risch,Mark E. Robson,Gustavo C. Rodriguez,Atocha Romero,Mary Anne Rossing,Mary Anne Rossing,Joseph H. Rothstein,Anja Rudolph,Ingo B. Runnebaum,Ritu Salani,Helga B. Salvesen,Helga B. Salvesen,Elinor J. Sawyer,Joellen M. Schildkraut,Joellen M. Schildkraut,Marjanka K. Schmidt,Rita K. Schmutzler,Andreas Schneeweiss,Minouk J. Schoemaker,Michael G. Schrauder,Fredrick R. Schumacher,Ira Schwaab,Giulietta Scuvera,Thomas A. Sellers,Gianluca Severi,Gianluca Severi,Gianluca Severi,Caroline M. Seynaeve,Mitul Shah,Martha J. Shrubsole,Nadeem Siddiqui,Weiva Sieh,Jacques Simard,Christian F. Singer,Olga M. Sinilnikova,Dominiek Smeets,Christof Sohn,Maria Soller,Honglin Song,Penny Soucy,Melissa C. Southey,Christa Stegmaier,Dominique Stoppa-Lyonnet,Dominique Stoppa-Lyonnet,Lara Sucheston,Anthony J. Swerdlow,Ingvild L. Tangen,Ingvild L. Tangen,Muy-Kheng Tea,Manuel R. Teixeira,Kathryn L. Terry,Kathryn L. Terry,Mary Beth Terry,Mads Thomassen,Pamela J. Thompson,Laima Tihomirova,Marc Tischkowitz,Amanda E. Toland,Rob A. E. M. Tollenaar,Ian Tomlinson,Diana Torres,Diana Torres,Thérèse Truong,Helen Tsimiklis,Nadine Tung,Shelley S. Tworoger,Shelley S. Tworoger,Jonathan Tyrer,Celine M. Vachon,Laura J. van't Veer,Anne M. van Altena,C. J. van Asperen,David Van Den Berg,Ans M.W. van den Ouweland,Helena C. van Doorn,Els Van Nieuwenhuysen,Elizabeth J. van Rensburg,Ignace Vergote,Senno Verhoef,Robert A. Vierkant,Joseph Vijai,Allison F. Vitonis,Allison F. Vitonis,Anna von Wachenfeldt,Christine Walsh,Qin Wang,Shan Wang-Gohrke,Barbara Wappenschmidt,Maren Weischer,Jeffrey N. Weitzel,Caroline Weltens,Nicolas Wentzensen,Alice S. Whittemore,Lynne R. Wilkens,Robert Winqvist,Robert Winqvist,Anna H. Wu,Xifeng Wu,Hannah P. Yang,Daniela Zaffaroni,M. Pilar Zamora,Wei Zheng,Argyrios Ziogas,Georgia Chenevix-Trench,Paul D.P. Pharoah,Matti A. Rookus,Maartje J. Hooning,Ellen L. Goode +391 more
TL;DR: Genotyping rs61764370 is not associated with risk of ovarian or breast cancer nor with clinical outcome for patients with these cancers, and genotyping this variant has no clinical utility related to the prediction or management of these cancers.
Journal ArticleDOI
Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers
Amanda B. Spurdle,Louise Marquart,Lesley McGuffog,Sue Healey,Olga M. Sinilnikova,Fei Wan,Xiaoqing Chen,Jonathan Beesley,Christian F. Singer,Anne Catharine Dressler,Daphne Gschwantler-Kaulich,Joanne L. Blum,Nadine Tung,Jeff Weitzel,Henry T. Lynch,Judy Garber,Douglas F. Easton,Susan Peock,Margaret Cook,Clare Oliver,Debra Frost,Don M. Conroy,D. Gareth Evans,Fiona Lalloo,Ros Eeles,Louise Izatt,Rosemarie Davidson,Carol Chu,Diana Eccles,Christina G. Selkirk,Mary B. Daly,Claudine Isaacs,Dominique Stoppa-Lyonnet,Olga M. Sinilnikova,Olga M. Sinilnikova,Bruno Buecher,Muriel Belotti,Sylvie Mazoyer,Laure Barjhoux,Laure Barjhoux,Carole Verny-Pierre,Carole Verny-Pierre,Christine Lasset,Hélène Dreyfus,Pascal Pujol,Marie Agnés Collonge-Rame,Matti A. Rookus,Senno Verhoef,Mieke Kriege,Nicoline Hoogerbrugge,Margreet G. E. M. Ausems,Theo A. M. van Os,Juul T. Wijnen,Peter Devilee,Hanne Meijers-Heijboer,Marinus J. Blok,Tuomas Heikkinen,Heli Nevanlinna,Anna Jakubowska,Jan Lubinski,Tomasz Huzarski,Tomasz Byrski,Francine Durocher,Fergus J. Couch,Noralane M. Lindor,Xianshu Wang,Mads Thomassen,Susan M. Domchek,Katherine L. Nathanson,Maria A. Caligo,Helena Jernström,Annelie Liljegren,Hans Ehrencrona,Per Karlsson,Patricia A. Ganz,Olufunmilayo I. Olopade,Gail E. Tomlinson,Susan L. Neuhausen,Antonis C. Antoniou,Georgia Chenevix-Trench,Timothy R. Rebbeck +80 more
TL;DR: Evidence to date does not support a role for BARD1 variation, including the Cy557Ser variant, as a modifier of risk in BRCA1/2 mutation carriers, according to single SNP analysis.