M
Martina Mueller
Researcher at Ludwig Maximilian University of Munich
Publications - 7
Citations - 2851
Martina Mueller is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Odds ratio & Genome-wide association study. The author has an hindex of 5, co-authored 7 publications receiving 2782 citations.
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Hundreds of variants clustered in genomic loci and biological pathways affect human height
Hana Lango Allen,Karol Estrada,Guillaume Lettre,Sonja I. Berndt,Michael N. Weedon,Fernando Rivadeneira,Cristen J. Willer,Anne U. Jackson,Sailaja Vedantam,Soumya Raychaudhuri,Teresa Ferreira,Andrew R. Wood,Robert J. Weyant,Ayellet V. Segrè,Elizabeth K. Speliotes,Eleanor Wheeler,Nicole Soranzo,Ju-Hyun Park,Jian Yang,Daniel F. Gudbjartsson,Nancy L. Heard-Costa,Joshua C. Randall,Lu Qi,Albert V. Smith,Reedik Maegi,Tomi Pastinen,Liming Liang,Iris M. Heid,Jian'an Luan,Gudmar Thorleifsson,Thomas W. Winkler,Michael E. Goddard,Ken Sin Lo,Cameron D. Palmer,Tsegaselassie Workalemahu,Yurii S. Aulchenko,Åsa Johansson,M. Carola Zillikens,Mary F. Feitosa,Tõnu Esko,Toby Johnson,Shamika Ketkar,Peter Kraft,Massimo Mangino,Inga Prokopenko,Devin Absher,Eva Albrecht,Florian Ernst,Nicole L. Glazer,Caroline Hayward,Jouke-Jan Hottenga,Kevin B. Jacobs,Joshua W. Knowles,Zoltán Kutalik,Keri L. Monda,Ozren Polasek,Michael Preuss,Nigel W. Rayner,Neil R. Robertson,Valgerdur Steinthorsdottir,Jonathan Tyrer,Benjamin F. Voight,Fredrik Wiklund,Jianfeng Xu,Jing Hua Zhao,Dale R. Nyholt,Niina Pellikka,Markus Perola,John R. B. Perry,Ida Surakka,Mari-Liis Tammesoo,Elizabeth L. Altmaier,Najaf Amin,Thor Aspelund,Tushar Bhangale,Gabrielle Boucher,Daniel I. Chasman,Constance Chen,Lachlan J. M. Coin,Mark E. Cooper,Anna L. Dixon,Quince Gibson,Elin Grundberg,Ke Hao,M. Juhani Junttila,Lee M. Kaplan,Johannes Kettunen,Inke R. Koenig,Tony Kwan,Robert Lawrence,Douglas F. Levinson,Mattias Lorentzon,Barbara McKnight,Andrew P. Morris,Martina Mueller,Julius S. Ngwa,Shaun Purcell,Suzanne Rafelt,Rany M. Salem,Erika Salvi,Serena Sanna,Jianxin Shi,Ulla Sovio,John R. Thompson,Michael C. Turchin,Liesbeth Vandenput,Dominique J. Verlaan,Veronique Vitart,Charles C. White,Andreas Ziegler,Peter Almgren,Anthony J. Balmforth,Harry Campbell,Lorena Citterio,Alessandro De Grandi,Anna F. Dominiczak,Jubao Duan,Paul Elliott,Roberto Elosua,Johan G. Eriksson,Nelson B. Freimer,Eco J. C. de Geus,Nicola Glorioso,Shen Haiqing,Anna-Liisa Hartikainen,Aki S. Havulinna,Andrew A. Hicks,Jennie Hui,Wilmar Igl,Thomas Illig,Antti Jula,Eero Kajantie,Tuomas O. Kilpelaeinen,Markku Koiranen,Ivana Kolcic,Seppo Koskinen,Peter Kovacs,Jaana Laitinen,Jianjun Liu,Marja-Liisa Lokki,Ana Marušić,Andrea Maschio,Thomas Meitinger,Antonella Mulas,Guillaume Paré,Alex N. Parker,John F. Peden,Astrid Petersmann,Irene Pichler,Kirsi H. Pietiläinen,Anneli Pouta,Martin Riddertrale,Jerome I. Rotter,Jennifer G. Sambrook,Alan R. Sanders,Carsten Oliver Schmidt,Juha Sinisalo,Jan Smit,Heather M. Stringham,G. Bragi Walters,Elisabeth Widen,Sarah H. Wild,Gonneke Willemsen,Laura Zagato,Lina Zgaga,Paavo Zitting,Helene Alavere,Martin Farrall,Wendy L. McArdle,Mari Nelis,Marjolein Peters,Samuli Ripatti,Joyce B. J. vVan Meurs,Katja K.H. Aben,Kristin G. Ardlie,Jacques S. Beckmann,John Beilby,Richard N. Bergman,Sven Bergmann,Francis S. Collins,Daniele Cusi,Martin den Heijer,Gudny Eiriksdottir,Pablo V. Gejman,Alistair S. Hall,Anders Hamsten,Heikki V. Huikuri,Carlos Iribarren,Mika Kähönen,Jaakko Kaprio,Sekar Kathiresan,Lambertus A. Kiemeney,Thomas D. Kocher,Lenore J. Launer,Terho Lehtimäki,Olle Melander,Thomas H. Mosley,Arthur W. Musk,Markku S. Nieminen,Christopher J. O'Donnell,Claes Ohlsson,Ben A. Oostra,Lyle J. Palmer,Olli T. Raitakari,Paul M. Ridker,John D. Rioux,Aila Rissanen,Carlo Rivolta,Heribert Schunkert,Alan R. Shuldiner,David S. Siscovick,Michael Stumvoll,Anke Toenjes,Jaakko Tuomilehto,Gert-Jan B. van Ommen,Jorma Viikari,Andrew C. Heath,Nicholas G. Martin,Grant W. Montgomery,Michael A. Province,Manfred Kayser,Alice M. Arnold,Larry D. Atwood,Eric Boerwinkle,Stephen J. Chanock,Panos Deloukas,Christian Gieger,Henrik Grönberg,Per Hall,Andrew T. Hattersley,Christian Hengstenberg,Wolfgang Hoffman,G. Mark Lathrop,Veikko Salomaa,Stefan Schreiber,Manuela Uda,Dawn M. Waterworth,Alan F. Wright,Themistocles L. Assimes,Inês Barroso,Albert Hofman,Karen L. Mohlke,Dorret I. Boomsma,Mark J. Caulfield,L. Adrienne Cupples,Jeanette Erdmann,Caroline S. Fox,Vilmundur Gudnason,Ulf Gyllensten,Tamara B. Harris,Richard B. Hayes,Marjo-Ritta Jarvelin,Vincent Mooser,Patricia B. Munroe,Willem H. Ouwehand,Brenda W.J.H. Penninx,Peter P. Pramstaller,Thomas Quertermous,Igor Rudan,Nilesh J. Samani,Tim D. Spector,Henry Voelzke,Hugh Watkins,James F. Wilson,Leif Groop,Talin Haritunians,Frank B. Hu,Robert C. Kaplan,Andres Metspalu,Kari E. North,David Schlessinger,Nicholas J. Wareham,David J. Hunter,Jeffrey R. O'Connell,David P. Strachan,H. Erich Schadt,Unnur Thorsteinsdottir,Leena Peltonen,André G. Uitterlinden,Peter M. Visscher,Nilanjan Chatterjee,Ruth J. F. Loos,Michael Boehnke,Mark I. McCarthy,Erik Ingelsson,Cecilia M. Lindgren,Gonçalo R. Abecasis,Kari Stefansson,Timothy M. Frayling,Joel N. Hirschhorn +289 more
TL;DR: In this paper, the authors show that hundreds of genetic variants, in at least 180 loci, influence adult height, a highly heritable and classic polygenic trait, revealing patterns with important implications for genetic studies of common human diseases and traits.
Journal ArticleDOI
Common variants in KCNN3 are associated with lone atrial fibrillation
Patrick T. Ellinor,Kathryn L. Lunetta,Kathryn L. Lunetta,Nicole L. Glazer,Arne Pfeufer,Alvaro Alonso,Mina K. Chung,Moritz F. Sinner,Paul I.W. de Bakker,Paul I.W. de Bakker,Martina Mueller,Steven A. Lubitz,Ervin R. Fox,Dawood Darbar,Nicholas L. Smith,Nicholas L. Smith,Jonathan D. Smith,Renate B. Schnabel,Elsayed Z. Soliman,Kenneth Rice,David R. Van Wagoner,Britt-M. Beckmann,Charlotte van Noord,Ke Wang,Georg Ehret,Georg Ehret,Jerome I. Rotter,Stanley L. Hazen,Gerhard Steinbeck,Albert V. Smith,Lenore J. Launer,Tamara B. Harris,Seiko Makino,Mari Nelis,Mari Nelis,David J. Milan,Siegfried Perz,Tõnu Esko,Tõnu Esko,Anna Köttgen,Susanne Moebus,Christopher Newton-Cheh,Christopher Newton-Cheh,Man Li,Stefan Möhlenkamp,Thomas J. Wang,Thomas J. Wang,W. H. Linda Kao,Ramachandran S. Vasan,Ramachandran S. Vasan,Markus M. Nöthen,Markus M. Nöthen,Calum A. MacRae,Bruno H. Stricker,Albert Hofman,André G. Uitterlinden,Daniel Levy,Eric Boerwinkle,Andres Metspalu,Andres Metspalu,Eric J. Topol,Aravinda Chakravarti,Vilmundur Gudnason,Bruce M. Psaty,Bruce M. Psaty,Dan M. Roden,Thomas Meitinger,H.-Erich Wichmann,Jacqueline C.M. Witteman,John Barnard,Dan E. Arking,Emelia J. Benjamin,Emelia J. Benjamin,Susan R. Heckbert,Susan R. Heckbert,Stefan Kääb +75 more
TL;DR: A meta-analysis of genome-wide association studies conducted using 1,335 individuals with lone AF and 12,844 unaffected individuals found an association on chromosome 1q21 to lone AF, which is intronic to KCNN3, which encodes a potassium channel protein involved in atrial repolarization.
Journal ArticleDOI
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.
Emelia J. Benjamin,Emelia J. Benjamin,Kenneth Rice,Dan E. Arking,Arne Pfeufer,Charlotte van Noord,Albert V. Smith,Renate B. Schnabel,Renate B. Schnabel,Joshua C. Bis,Eric Boerwinkle,Moritz F. Sinner,Abbas Dehghan,Steven A. Lubitz,Ralph B. D'Agostino,Ralph B. D'Agostino,Thomas Lumley,Georg Ehret,Jan Heeringa,Thor Aspelund,Christopher Newton-Cheh,Christopher Newton-Cheh,Martin G. Larson,Martin G. Larson,Kristin D. Marciante,Elsayed Z. Soliman,Fernando Rivadeneira,Thomas J. Wang,Thomas J. Wang,Gudny Eiriksdottir,Daniel Levy,Daniel Levy,Bruce M. Psaty,Bruce M. Psaty,Man Li,Alanna M. Chamberlain,Albert Hofman,Ramachandran S. Vasan,Tamara B. Harris,Jerome I. Rotter,W. H. Linda Kao,Sunil K. Agarwal,Bruno H. Stricker,Ke Wang,Lenore J. Launer,Nicholas L. Smith,Nicholas L. Smith,Aravinda Chakravarti,André G. Uitterlinden,Philip A. Wolf,Philip A. Wolf,Nona Sotoodehnia,Anna Köttgen,Cornelia M. van Duijn,Thomas Meitinger,Martina Mueller,Siegfried Perz,Gerhard Steinbeck,H.-Erich Wichmann,Kathryn L. Lunetta,Kathryn L. Lunetta,Susan R. Heckbert,Susan R. Heckbert,Vilmundur Gudnason,Alvaro Alonso,Stefan Kääb,Patrick T. Ellinor,Jacqueline C.M. Witteman +67 more
TL;DR: Meta-analyses of genome-wide association studies for atrial fibrillation in participants from five community-based cohorts identified a new locus for AF as ZFHX3, rs2106261, which was replicated in an independent cohort from the German AF Network.
Journal ArticleDOI
Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease
Adam S. Butterworth,Peter S. Braund,Martin Farrall,Robert J. Hardwick,Danish Saleheen,J F Peden,Nicole Soranzo,John C. Chambers,Suthesh Sivapalaratnam,Marcus E. Kleber,Brendan J. Keating,Atif Qasim,Norman Klopp,Jeanette Erdmann,Themistocles L. Assimes,Stephen G. Ball,Anthony J. Balmforth,Timothy A. Barnes,Hanneke Basart,Jens Baumert,Connie R. Bezzina,Eric Boerwinkle,Bernhard O. Boehm,Jessy Brocheton,Peter Bugert,François Cambien,Robert Clarke,Veryan Codd,Rory Collins,David Couper,L. Adrienne Cupples,Jonas S.S.G. de Jong,Patrick Diemert,Kenechi Ejebe,Clara C. Elbers,Paul Elliott,Myriam Fornage,Maria Grazia Franzosi,Philippe M. Frossard,Stephen F. Garner,Anuj Goel,Alison H. Goodall,Christian Hengstenberg,Sarah E. Hunt,John J.P. Kastelein,Olaf H. Klungel,Harald Klüterr,Kerstin Koch,Inke R. König,Angad S. Kooner,Reijo Laaksonen,Mark Lathrop,Mingyao Li,Kiang Liu,Ruth McPherson,Muntaser D. Musameh,Solomon K. Musani,Christopher P. Nelson,Christopher J. O'Donnell,Halit Ongen,George J. Papanicolaou,Annette Peters,Bas J M Peters,Simon C. Potter,Bruce M. Psaty,Liming Qu,Daniel J. Rader,Asif Rasheed,Catherine M. Rice,James Scott,Udo Seedorf,Joban Sehmi,Nona Sotoodehnia,Klaus Stark,Jonathan Stephens,C. Ellen van der Schoot,Yvonne T. van der Schouw,Unnur Thorsteinsdottir,Maciej Tomaszewski,Pim van der Harst,Ramachandran S. Vasan,Arthur A.M. Wilde,Christina Willenborg,Bernhard R. Winkelmann,Moazzam Zaidi,Weihua Zhang,Andreas Ziegler,Paul I.W. de Bakker,Wolfgang Koenig,Winfried März,Mieke D. Trip,Muredach P. Reilly,Sekar Kathiresan,Heribert Schunkert,Anders Hamsten,Alistair S. Hall,Jaspal S. Kooner,Simon G. Thompson,John R. Thompson,Panos Deloukas,Willem H. Ouwehand,Hugh Watkins,John Danesh,Nilesh J. Samani,Timothy A. Barnes,Timothy A. Barnes,Suzanne Rafelt,Nienke Bruinsma,Lukas R.C. Dekker,José P. Henriques,Karel T. Koch,Karel T. Koch,Robbert J. de Winter,Marco Alings,Cor F. Allaart,Anton P.M. Gorgels,Freek W. Verheugt,Martina Mueller,Christa Meisinger,Stephanie DerOhannessian,Nehal N. Mehta,Jane F. Ferguson,Hakon Hakonarson,William H. Matthai,Robert L. Wilensky,Jemma C. Hopewell,Sarah Parish,Pamela Linksted,J. Notman,Hector M. González,A. Young,T. Ostley,A. Munday,N. Goodwin,V. Verdon,Svati H. Shah,Laura K. Cobb,Cathryn Edwards,Carol A. Mathews,R. Gunter,J. Benham,Christopher Davies,M. Cobb,J. Crowther,Arthur Mark Richards,M. Silver,S. Tochlin,S. Mozley,Sarah Clark,M. Radley,K. Kourellias,Per Georg Olsson,Simona Barlera,Gianni Tognoni,Stephan Rust,Gerd Assmann,Simon Heath,Diana Zelenika,Ivo Gut,Fiona Green,John F. Peden,Anette Aly,Karolina Anner,Karin Björklund,Gun Blomgren,Barbro Cederschiöld,Karin Danell-Toverud,Per Eriksson,Ulla Grundstedt,Merja Heinonen,Mai Lis Hellénius,Ferdinand M. van't Hooft,Karin Husman,Jacob Lagercrantz,Anita Larsson,Malin Larsson,Magnus Mossfeldt,Anders Mälarstig,Gunnar O Olsson,Maria Sabater-Lleal,Bengt Sennblad,Angela Silveira,Rona J. Strawbridge,Birgitta Söderholm,John Öhrvik,Khan Shah Zaman,Nadeem Hayat Mallick,Muhammad Azhar,Abdus Samad,M. Ishaq,Nabi Shah,Maria Samuel,Muredach P. Reilly,Muredach P. Reilly,Hilma Holm,Michael Preuss,Alexandre F.R. Stewart,Maja Barbalić,Christian Gieger,Devin Absher,Zouhair Aherrahrou,Hooman Allayee,David Altshuler,Sonia S. Anand,Karl Andersen,Jeffrey L. Anderson,Diego Ardissino,Lewis C. Becker,Diane M. Becker,Klaus Berger,Joshua C. Bis,S. Matthijs Boekholdt,Morris J. Brown,Mary Susan Burnett,Ian Buysschaert,John F. Carlquist,Li Chen,Robert W. Davies,George Dedoussis,Abbas Dehghan,Serkalem Demissie,Joseph M. Devaney,Ron Do,Angela Doering,Nour Eddine El Mokhtari,Stephen G. Ellis,Roberto Elosua,James C. Engert,Stephen E. Epstein,Ulf de Faire,Marcus Fischer,Aaron R. Folsom,Jennifer Freyer,Bruna Gigante,Domenico Girelli,Solveig Gretarsdottir,Vilmundur Gudnason,Jeffrey R. Gulcher,Stephanie Tennstedt,Eran Halperin,Naomi Hammond,Stanley L. Hazen,Albert Hofman,Benjamin D. Horne,Thomas Illig,Carlos Iribarren,Gregory T. Jones,J. Wouter Jukema,Michael A. Kaiser,Lee M. Kaplan,Kay-Tee Khaw,Joshua W. Knowles,G. Kolovou,Augustine Kong,Diether Lambrechts,Karin Leander,Wolfgang Lieb,Guillaume Lettre,Christina Loley,Andrew J. Lotery,Pier Mannuccio Mannucci,Seraya Maouche,Nicola Martinelli,Pascal P. McKeown,Thomas Meitinger,Olle Melander,Pier Angelica Merlini,Vincent Mooser,Thomas M. Morgan,Thomas W. Mühleisen,Joseph B. Muhlestein,Kiran Musunuru,Janja Nahrstaedt,Markus M. Nöthen,Oliviero Olivieri,Flora Peyvandi,Riyaz S. Patel,Christopher Patterson,Arshed A. Quyyumi,Loukianos S. Rallidis,Frits R. Roosendaal,Diana Rubin,Veikko Salomaa,M. Lourdes Sampietro,M. S. Sandhu,Eric E. Schadt,Arne Schäfer,Arne Schillert,Stefan Schreiber,Jürgen Schrezenmeir,Stephen M. Schwartz,David S. Siscovick,Mohan U. Sivananthan,Albert V. Smith,Tamara B. Smith,Jaapjan D. Snoep,John A. Spertus,Kari Stefansson,Kathy Stirrups,Monika Stoll,W.H. Wilson Tang,Gudmundur Thorgeirsson,Gudmar Thorleifsson,André G. Uitterlinden,Andre M. van Rij,Benjamin F. Voight,Nicholas J. Wareham,George A. Wells,H.-Erich Wichmann,Jaqueline C M Witteman,Benjamin J. Wright,Shu Ye,Thomas Quertermous,Stefan Blankenberg,Robert Roberts,N. Charlotte Onland-Moret,Jessica van Setten,W. M. Monique Verschuren,Jolanda M. A. Boer,Cisca Wijmenga,Marten H. Hofker,Anke-Hilse Maitland-van der Zee,Anthonius de Boer,Diederick E. Grobbee,Tony Attwood,Stephanie Belz,Peter S. Braund,Peter S. Braund,Jason D. Cooper,Abi Crisp-Hihn,Nicola Foad,Jay Gracey,Emma Gray,Rhian Gwilliams,Susanne Heimerl,Jennifer Jolley,Unni Krishnan,Heather Lloyd-Jones,Ingrid Lugauer,Per Lundmark,Jasbir S. Moore,David Muir,Elizabeth Murray,Jessica Neudert,David Niblett,Karen O'Leary,Helen Pollard,Angela Rankin,Catherine M. Rice,Hendrik B. Sager,Jennifer G. Sambrook,Gerd Schmitz,Michael Scholz,Laura Schroeder,Ann Christine Syvannen,Chris Wallace +355 more
TL;DR: This large-scale gene-centric analysis has identified several novel genes for CAD that relate to diverse biochemical and cellular functions and clarified the literature with regard to many previously suggested genes.
European lactase persistence genotype shows evidence of association with increase in body mass index
Johannes Kettunen,Kaisa Silander,Olli Saarela,Najaf Amin,Martina Mueller,Nicholas J. Timpson,Ida Surakka,Samuli Ripatti,Jaana Laitinen,Anna-Liisa Hartikainen,Anneli Pouta,Päivi Lahermo,Verneri Anttila,Satu Männistö,Antti Jula,Jarmo Virtamo,Veikko Salomaa,Terho Lehtimäki,Olli T. Raitakari,Christian Gieger,Erich Wichmann,Cornelia M. van Duijn,George Davey Smith,Mark I. McCarthy,Marjo-Riitta Järvelin,Markus Perola,Leena Peltonen +26 more