M
Michael Boehnke
Researcher at University of Michigan
Publications - 540
Citations - 155551
Michael Boehnke is an academic researcher from University of Michigan. The author has contributed to research in topics: Genome-wide association study & Type 2 diabetes. The author has an hindex of 152, co-authored 511 publications receiving 136681 citations. Previous affiliations of Michael Boehnke include SUNY Downstate Medical Center & Norwegian University of Science and Technology.
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Journal ArticleDOI
Association of the calpain-10 gene with type 2 diabetes in Europeans: Results of pooled and meta-analyses
Takafumi Tsuchiya,Peter Schwarz,Laura del Bosque-Plata,M. Geoffrey Hayes,Christian Dina,Philippe Froguel,G. Wayne Towers,G. Wayne Towers,Sabine Fischer,Theodora Temelkova-Kurktschiev,Hannes Rietzsch,Juergen Graessler,Josef Vcelak,Daniela Palyzová,Thomas Selisko,Bela Bendlova,Jan Schulze,Ulrich Julius,Markolf Hanefeld,Michael N. Weedon,Julie Evans,Timothy M. Frayling,Andrew T. Hattersley,Marju Orho-Melander,Leif Groop,Maciej T. Malecki,Torben Hansen,Oluf Pedersen,Tasha E. Fingerlin,Michael Boehnke,Craig L. Hanis,Nancy J. Cox,Graeme I. Bell +32 more
TL;DR: The pooled and meta-analyses as well as the linkage disequilibrium and haplotype diversity studies suggest a role for genetic variation in CAPN10 affecting risk of T2D in Europeans.
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Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
Jonas B. Nielsen,Lars G. Fritsche,Lars G. Fritsche,Wei Zhou,Tanya M. Teslovich,Oddgeir L. Holmen,Stefan Gustafsson,Maiken Elvestad Gabrielsen,Ellen M. Schmidt,Robin N Beaumont,Brooke N. Wolford,Maoxuan Lin,Chad M. Brummett,Michael Preuss,Lena Refsgaard,Erwin P. Bottinger,Sarah E. Graham,Ida Surakka,Yunhan Chu,Anne Heidi Skogholt,Håvard Dalen,Håvard Dalen,Alan P. Boyle,Hakan Oral,Todd J. Herron,Jacob O. Kitzman,José Jalife,José Jalife,Jesper Hastrup Svendsen,Morten S. Olesen,Inger Njølstad,Maja-Lisa Løchen,Aris Baras,Omri Gottesman,Anthony Marcketta,Colm O'Dushlaine,Marylyn D. Ritchie,Tom Wilsgaard,Ruth J. F. Loos,Timothy M. Frayling,Michael Boehnke,Michael Boehnke,Erik Ingelsson,Erik Ingelsson,David J. Carey,Frederick E. Dewey,Hyun Min Kang,Gonçalo R. Abecasis,Gonçalo R. Abecasis,Kristian Hveem,Kristian Hveem,Cristen J. Willer +51 more
TL;DR: Pathway and functional enrichment analyses suggested that many AF-associated genetic variants act through a mechanism of impaired muscle cell differentiation and tissue formation during fetal heart development.
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Examination of genetic linkage of chromosome 15 to schizophrenia in a large Veterans Affairs Cooperative Study sample.
Debby Tsuang,Debby Tsuang,Andrew D. Skol,Stephen V. Faraone,Stephen V. Faraone,Stephen V. Faraone,Stephen F. Bingham,Keith A. Young,Sarita Prabhudesai,S.L. Haverstock,Felicitas Mena,A. Shrikumar Menon,Darren Bisset,John R. Pepple,John R. Pepple,John R. Pepple,Fred Sauter,Charlene Baldwin,David G. Weiss,Joseph F. Collins,Michael Boehnke,Gerard D. Schellenberg,Gerard D. Schellenberg,Ming T. Tsuang +23 more
TL;DR: In this paper, the authors reported genetic linkage evidence for a schizophrenia gene on chromosome 15q using 166 schizophrenia families, each with two or more affected subjects, including northern European American families and African American kindreds.
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Common variants in maturity-onset diabetes of the young genes contribute to risk of type 2 diabetes in Finns.
Lori L. Bonnycastle,Cristen J. Willer,Karen N. Conneely,Anne U. Jackson,Cecily P. Burrill,Richard M. Watanabe,Peter S. Chines,Narisu Narisu,Laura J. Scott,Sareena T. Enloe,Amy J. Swift,William L. Duren,Heather M. Stringham,Michael R. Erdos,Nancy Riebow,Thomas A. Buchanan,Timo T. Valle,Jaakko Tuomilehto,Jaakko Tuomilehto,Richard N. Bergman,Karen L. Mohlke,Michael Boehnke,Francis S. Collins +22 more
TL;DR: In this article, the authors examined the other five known MODY genes for association with type 2 diabetes in Finnish individuals, including GCK, HNF1A and NEUROD1.
Journal ArticleDOI
Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans.
Jedidiah Carlson,Adam E. Locke,Matthew Flickinger,Matthew Zawistowski,Shawn Levy,Richard M. Myers,Michael Boehnke,Hyun Min Kang,Laura J. Scott,Jun Li,Sebastian Zöllner +10 more
TL;DR: These estimates are more accurate than previously published results based on ancestrally older variants without considering genomic features, and provide the most refined portrait to date of the factors contributing to genome-wide variability of the human germline mutation rate.