M
Michael Boehnke
Researcher at University of Michigan
Publications - 540
Citations - 155551
Michael Boehnke is an academic researcher from University of Michigan. The author has contributed to research in topics: Genome-wide association study & Type 2 diabetes. The author has an hindex of 152, co-authored 511 publications receiving 136681 citations. Previous affiliations of Michael Boehnke include SUNY Downstate Medical Center & Norwegian University of Science and Technology.
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Journal ArticleDOI
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Janina S. Ried,Janina M. Jeff,Audrey Y. Chu,Jennifer L. Bragg-Gresham,Jenny van Dongen,Jennifer E. Huffman,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Gemma Cadby,Niina Eklund,Joel Eriksson,Tõnu Esko,Tõnu Esko,Mary F. Feitosa,Anuj Goel,Mathias Gorski,Caroline Hayward,Nancy L. Heard-Costa,Nancy L. Heard-Costa,Anne U. Jackson,Eero Jokinen,Stavroula Kanoni,Stavroula Kanoni,Kati Kristiansson,Kati Kristiansson,Zoltán Kutalik,Zoltán Kutalik,Jari Lahti,Jian'an Luan,Reedik Mägi,Reedik Mägi,Anubha Mahajan,Massimo Mangino,Carolina Medina-Gomez,Keri L. Monda,Keri L. Monda,Ilja M. Nolte,Louis Pérusse,Inga Prokopenko,Inga Prokopenko,Lu Qi,Lynda M. Rose,Erika Salvi,Megan T. Smith,Harold Snieder,Alena Standáková,Yun Ju Sung,Ioanna Tachmazidou,Alexander Teumer,Gudmar Thorleifsson,Pim van der Harst,Ryan W. Walker,Sophie R. Wang,Sophie R. Wang,Sarah H. Wild,Sara M. Willems,Andrew Wong,Weihua Zhang,Weihua Zhang,Eva Albrecht,Alexessander Couto Alves,Stephan J. L. Bakker,Cristina Barlassina,Traci M. Bartz,John Beilby,Claire Bellis,Claire Bellis,Richard N. Bergman,Sven Bergmann,Sven Bergmann,John Blangero,Matthias Blüher,Eric Boerwinkle,Lori L. Bonnycastle,Stefan R. Bornstein,Marcel Bruinenberg,Harry Campbell,Yii-Der Ida Chen,Charleston W. K. Chiang,Peter S. Chines,Francis S. Collins,Fracensco Cucca,L. Adrienne Cupples,Francesca D'Avila,Eco J. C. de Geus,George Dedoussis,Maria Dimitriou,Maria Dimitriou,Angela Döring,Johan G. Eriksson,Johan G. Eriksson,Aliki-Eleni Farmaki,Martin Farrall,Teresa Ferreira,Krista Fischer,Nita G. Forouhi,Nele Friedrich,Anette P. Gjesing,Nicola Glorioso,Mariaelisa Graff,Harald Grallert,Niels Grarup,Jürgen Gräßler,Jagvir Grewal,Jagvir Grewal,Anders Hamsten,Marie Neergaard Harder,Catharina A. Hartman,Maija Hassinen,Nicholas D. Hastie,Andrew T. Hattersley,Aki S. Havulinna,Markku Heliövaara,Hans L. Hillege,Albert Hofman,Oddgeir L. Holmen,Georg Homuth,Jouke-Jan Hottenga,Jennie Hui,Lise Lotte N. Husemoen,Pirro G. Hysi,Aaron Isaacs,Till Ittermann,Shapour Jalilzadeh,Alan James,Torben Jørgensen,Torben Jørgensen,Pekka Jousilahti,Antti Jula,Johanne Marie Justesen,Anne E. Justice,Mika Kähönen,Maria Karaleftheri,Kay-Tee Khaw,Sirkka Keinänen-Kiukaanniemi,Leena Kinnunen,Paul Knekt,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Ivana Kolcic,Ishminder K. Kooner,Seppo Koskinen,Peter Kovacs,Theodosios Kyriakou,Tomi Laitinen,Claudia Langenberg,Claudia Langenberg,Alexandra M. Lewin,Peter Lichtner,Cecilia M. Lindgren,Cecilia M. Lindgren,Jaana Lindström,Allan Linneberg,Roberto Lorbeer,Mattias Lorentzon,Robert Luben,Valeriya Lyssenko,Valeriya Lyssenko,Satu Männistö,Paolo Manunta,Irene Mateo Leach,Wendy L. McArdle,Barbara McKnight,Barbara McKnight,Karen L. Mohlke,Evelin Mihailov,Lili Milani,Rebecca Mills,May E. Montasser,Andrew P. Morris,Andrew P. Morris,Gabriele Müller,Arthur W. Musk,Narisu Narisu,Ken K. Ong,Ken K. Ong,Ben A. Oostra,Clive Osmond,Aarno Palotie,Aarno Palotie,James S. Pankow,Lavinia Paternoster,Brenda W.J.H. Penninx,Irene Pichler,Maria Grazia Pilia,Ozren Polasek,Ozren Polasek,Peter P. Pramstaller,Olli T. Raitakari,Tuomo Rankinen,Dabeeru C. Rao,Nigel W. Rayner,Nigel W. Rayner,Rasmus Ribel-Madsen,Treva Rice,Marcus Richards,Marcus Richards,Paul M. Ridker,Fernando Rivadeneira,Kathy Ryan,Serena Sanna,Mark A. Sarzynski,Salome Scholtens,Robert A. Scott,Sylvain Sebert,Sylvain Sebert,Lorraine Southam,Lorraine Southam,Thomas Sparsø,Valgerdur Steinthorsdottir,Kathleen Stirrups,Kathleen Stirrups,Ronald P. Stolk,Konstantin Strauch,Heather M. Stringham,Morris A. Swertz,Amy J. Swift,Anke Tönjes,Emmanouil Tsafantakis,Peter J. van der Most,Jana V. van Vliet-Ostaptchouk,Liesbeth Vandenput,Erkki Vartiainen,Cristina Venturini,Cristina Venturini,Niek Verweij,Jorma Viikari,Veronique Vitart,Marie-Claude Vohl,Judith M. Vonk,Gérard Waeber,Elisabeth Widen,Gonneke Willemsen,Tom Wilsgaard,Thomas W. Winkler,Alan F. Wright,Laura M. Yerges-Armstrong,Jing Hua Zhao,M. Carola Zillikens,Dorret I. Boomsma,Claude Bouchard,John C. Chambers,John C. Chambers,John C. Chambers,Daniel I. Chasman,Daniele Cusi,Ron T. Gansevoort,Christian Gieger,Torben Hansen,Torben Hansen,Andrew A. Hicks,Frank B. Hu,Kristian Hveem,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Eero Kajantie,Eero Kajantie,Eero Kajantie,Jaspal S. Kooner,Jaspal S. Kooner,Jaspal S. Kooner,Diana Kuh,Johanna Kuusisto,Markku Laakso,Timo A. Lakka,Terho Lehtimäki,Andres Metspalu,Inger Njølstad,Claes Ohlsson,Albertine J. Oldehinkel,Lyle J. Palmer,Oluf Pedersen,Markus Perola,Markus Perola,Markus Perola,Annette Peters,Bruce M. Psaty,Bruce M. Psaty,Hannu Puolijoki,Rainer Rauramaa,Igor Rudan,Veikko Salomaa,Peter Schwarz,Alan R. Shudiner,Jan Smit,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Tim D. Spector,Kari Stefansson,Kari Stefansson,Michael Stumvoll,Angelo Tremblay,Jaakko Tuomilehto,Jaakko Tuomilehto,Jaakko Tuomilehto,André G. Uitterlinden,Matti Uusitupa,Uwe Völker,Peter Vollenweider,Nicholas J. Wareham,Hugh Watkins,James F. Wilson,Eleftheria Zeggini,Gonçalo R. Abecasis,Michael Boehnke,Ingrid B. Borecki,Panos Deloukas,Panos Deloukas,Panos Deloukas,Cornelia M. van Duijn,Caroline S. Fox,Caroline S. Fox,Leif Groop,Leif Groop,Iris M. Heid,David J. Hunter,Robert C. Kaplan,Mark I. McCarthy,Kari E. North,Jeffrey R. O'Connell,David Schlessinger,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,David P. Strachan,Timothy M. Frayling,Joel N. Hirschhorn,Joel N. Hirschhorn,Martina Müller-Nurasyid,Ruth J. F. Loos,Ruth J. F. Loos +330 more
TL;DR: In this paper, the authors examined whether genetic variants affect body shape as a composite phenotype that is represented by a combination of anthropometric traits, and identified six novel loci: LEMD2 and CD47 for AvPC1, RPS6KA5/C14orf159 and GANAB for AVPC3, and ARL15 and ANP32 for Avpc4.
Journal ArticleDOI
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Amy R. Bentley,Raymond Noordam,Yun Ju Sung,Karen Schwander,Thomas W. Winkler,Hermina Jakupović,Daniel I. Chasman,Daniel I. Chasman,Alisa K. Manning,Ioanna Ntalla,Hugues Aschard,Hugues Aschard,Michael R. Brown,Lisa de las Fuentes,Nora Franceschini,Xiuqing Guo,Dina Vojinovic,Stella Aslibekyan,Mary F. Feitosa,Minjung Kho,Solomon K. Musani,Melissa A. Richard,Heming Wang,Zhe Wang,Traci M. Bartz,Lawrence F. Bielak,Archie Campbell,Rajkumar Dorajoo,Virginia Fisher,Fernando Pires Hartwig,Fernando Pires Hartwig,Andrea R. V. R. Horimoto,Changwei Li,Kurt Lohman,Jonathan Marten,Xueling Sim,Albert V. Smith,Salman M. Tajuddin,Maris Alver,Marzyeh Amini,Mathilde Boissel,Jin-Fang Chai,Xu Chen,Jasmin Divers,Evangelos Evangelou,Evangelos Evangelou,Chuan Gao,Mariaelisa Graff,Sarah E. Harris,Meian He,Fang-Chi Hsu,Anne U. Jackson,Jing Hua Zhao,Aldi T. Kraja,Brigitte Kühnel,Federica Laguzzi,Leo-Pekka Lyytikäinen,Ilja M. Nolte,Rainer Rauramaa,Muhammad Riaz,Antonietta Robino,Rico Rueedi,Rico Rueedi,Heather M. Stringham,Fumihiko Takeuchi,Peter J. van der Most,Tibor V. Varga,Niek Verweij,Erin B. Ware,Wanqing Wen,Xiaoyin Li,Lisa R. Yanek,Najaf Amin,Donna K. Arnett,Eric Boerwinkle,Eric Boerwinkle,Marco Brumat,Brian E. Cade,Mickaël Canouil,Yii-Der Ida Chen,Maria Pina Concas,John M. C. Connell,Renée de Mutsert,H. Janaka de Silva,Paul S. de Vries,Ayse Demirkan,Jingzhong Ding,Charles B. Eaton,Jessica D. Faul,Yechiel Friedlander,Kelley Pettee Gabriel,Mohsen Ghanbari,Mohsen Ghanbari,Franco Giulianini,Chi Charles Gu,Dongfeng Gu,Tamara B. Harris,Jiang He,Sami Heikkinen,Chew-Kiat Heng,Chew-Kiat Heng,Steven C. Hunt,Steven C. Hunt,M. Arfan Ikram,Jost B. Jonas,Jost B. Jonas,Woon-Puay Koh,Pirjo Komulainen,José Eduardo Krieger,Stephen B. Kritchevsky,Zoltán Kutalik,Zoltán Kutalik,Johanna Kuusisto,Carl D. Langefeld,Claudia Langenberg,Lenore J. Launer,Karin Leander,Rozenn N. Lemaitre,Cora E. Lewis,Jingjing Liang,Jianjun Liu,Jianjun Liu,Reedik Mägi,Ani Manichaikul,Thomas Meitinger,Andres Metspalu,Yuri Milaneschi,Karen L. Mohlke,Thomas H. Mosley,Alison D. Murray,Mike A. Nalls,Ei-Ei Khaing Nang,Christopher P. Nelson,Christopher P. Nelson,Sotoodehnia Nona,Jill M. Norris,Chiamaka Vivian Nwuba,Jeffrey R. O'Connell,Nicholette D. Palmer,George J. Papanicolau,Raha Pazoki,Nancy L. Pedersen,Annette Peters,Patricia A. Peyser,Ozren Polasek,David J. Porteous,Alaitz Poveda,Olli T. Raitakari,Olli T. Raitakari,Stephen S. Rich,Neil Risch,Jennifer G. Robinson,Lynda M. Rose,Igor Rudan,Pamela J. Schreiner,Robert A. Scott,Stephen Sidney,Mario Sims,Jennifer A. Smith,Harold Snieder,Tamar Sofer,Tamar Sofer,John M. Starr,Barbara Sternfeld,Konstantin Strauch,Hua Tang,Kent D. Taylor,Michael Y. Tsai,Jaakko Tuomilehto,Jaakko Tuomilehto,André G. Uitterlinden,M. Yldau van der Ende,Diana van Heemst,Trudy Voortman,Melanie Waldenberger,Patrik Wennberg,Gregory P. Wilson,Yong-Bing Xiang,Jie Yao,Caizheng Yu,Jian-Min Yuan,Wei Zhao,Alan B. Zonderman,Diane M. Becker,Michael Boehnke,Donald W. Bowden,Ulf de Faire,Ian J. Deary,Paul Elliott,Tõnu Esko,Tõnu Esko,Barry I. Freedman,Philippe Froguel,Philippe Froguel,Paolo Gasparini,Christian Gieger,Norihiro Kato,Markku Laakso,Timo A. Lakka,Terho Lehtimäki,Patrik K. E. Magnusson,Albertine J. Oldehinkel,Brenda W.J.H. Penninx,Nilesh J. Samani,Nilesh J. Samani,Xiao-Ou Shu,Pim van der Harst,Jana V. van Vliet-Ostaptchouk,Peter Vollenweider,Lynne E. Wagenknecht,Ya X. Wang,Nicholas J. Wareham,David R. Weir,Tangchun Wu,Wei Zheng,Xiaofeng Zhu,Michele K. Evans,Paul W. Franks,Vilmundur Gudnason,Caroline Hayward,Bernardo L. Horta,Tanika N. Kelly,Yongmei Liu,Kari E. North,Alexandre C. Pereira,Paul M. Ridker,Paul M. Ridker,E. Shyong Tai,Rob M. van Dam,Ervin R. Fox,Sharon L.R. Kardia,Ching-Ti Liu,Dennis O. Mook-Kanamori,Michael A. Province,Susan Redline,Cornelia M. van Duijn,Jerome I. Rotter,Charles Kooperberg,W. James Gauderman,Bruce M. Psaty,Bruce M. Psaty,Kenneth Rice,Patricia B. Munroe,Myriam Fornage,L. Adrienne Cupples,L. Adrienne Cupples,Charles N. Rotimi,Alanna C. Morrison,Dabeeru C. Rao,Ruth J. F. Loos +251 more
TL;DR: In this article, the role of physical activity interactions in the genetic contribution to blood lipid levels was investigated, showing that higher levels of physical activities enhance the HDL cholesterol-increasing effects of the CLASP1, LHX1, and SNTA1 loci and attenuate the LDL cholesterol -increasing effect of the CNTNAP2 locus.
Journal Article
Selected locus and multiple panel models for radiation hybrid mapping.
TL;DR: Two new types of models for whole-genome radiation hybrid mapping using the general multipoint framework are developed, appropriate for mapping markers in the region of a selectable locus that was used in creation of the hybrids.
Journal ArticleDOI
A common biological basis of obesity and nicotine addiction
Thorgeir E. Thorgeirsson,Daniel F. Gudbjartsson,Patrick Sulem,Søren Besenbacher,Søren Besenbacher,Unnur Styrkarsdottir,Gudmar Thorleifsson,G B Walters,Helena Furberg,Patrick F. Sullivan,Jonathan Marchini,Jonathan Marchini,Mark I. McCarthy,Mark I. McCarthy,Valgerdur Steinthorsdottir,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Ida Surakka,Ida Surakka,Jacqueline M. Vink,Najaf Amin,Frank Geller,Thorunn Rafnar,Tõnu Esko,Tõnu Esko,Stefan Walter,Christian Gieger,Rajesh Rawal,Massimo Mangino,Inga Prokopenko,Inga Prokopenko,Reedik Mägi,Reedik Mägi,Reedik Mägi,Kaisu Keskitalo,Iris H Gudjonsdottir,Solveig Gretarsdottir,Hreinn Stefansson,Yurii S. Aulchenko,Mari Nelis,Mari Nelis,Katja K.H. Aben,Martin den Heijer,Nicole Soranzo,Nicole Soranzo,Ana M. Valdes,Claire J. Steves,André G. Uitterlinden,Albert Hofman,Anke Tönjes,Peter Kovacs,Jouke-Jan Hottenga,Gonneke Willemsen,Nicole Vogelzangs,Angela Döring,Norbert Dahmen,Norbert Dahmen,Barbara Nitz,Samuli Ripatti,Samuli Ripatti,M. Perola,M. Perola,Johannes Kettunen,Anna-Liisa Hartikainen,Anna-Liisa Hartikainen,Anneli Pouta,Jaana Laitinen,Matti Isohanni,Matti Isohanni,Shen Huei-Yi,Shen Huei-Yi,Maxine Allen,Maria Krestyaninova,Alistair S. Hall,John R. Thompson,Hogni Oskarsson,Thorarinn Tyrfingsson,Lambertus A. Kiemeney,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Veikko Salomaa,Michael Stumvoll,Tim D. Spector,H.-Erich Wichmann,Andres Metspalu,Andres Metspalu,Nilesh J. Samani,Brenda W.J.H. Penninx,Ben A. Oostra,Dorret I. Boomsma,Henning Tiemeier,Cornelia M. van Duijn,Jaakko Kaprio,Jaakko Kaprio,Jeffrey R. Gulcher,Yunjung Kim,Jennifer Dackor,Eric Boerwinkle,Nora Franceschini,Diego Ardissino,Luisa Bernardinelli,Luisa Bernardinelli,Pier Mannuccio Mannucci,Francesco Mauri,Piera Angelica Merlini,Devin Absher,Themistocles L. Assimes,Stephen P. Fortmann,Carlos Iribarren,Joshua W. Knowles,Thomas Quertermous,Luigi Ferrucci,Toshiko Tanaka,Joshua C. Bis,Curt D. Furberg,Talin Haritunians,Barbara McKnight,Bruce M. Psaty,Bruce M. Psaty,Kent D. Taylor,Evan L. Thacker,Peter Almgren,Leif Groop,Claes Ladenvall,Michael Boehnke,Anne U. Jackson,Karen L. Mohlke,Heather M. Stringham,Jaakko Tuomilehto,Jaakko Tuomilehto,Emelia J. Benjamin,Shih-Jen Hwang,Daniel Levy,Sarah R. Preis,Ramachandran S. Vasan,Jubao Duan,Pablo V. Gejman,Douglas F. Levinson,Alan R. Sanders,Jianxin Shi,Esther H. Lips,James McKay,Antonio Agudo,Luigi Barzan,Vladimir Bencko,Simone Benhamou,Xavier Castellsagué,Cristina Canova,David I. Conway,Eleonora Fabianova,Lenka Foretova,Vladimir Janout,Claire M. Healy,Ivana Holcatova,Kristina Kjærheim,Pagona Lagiou,Jolanta Lissowska,Ray Lowry,Tatiana V. Macfarlane,Dana Mates,Lorenzo Richiardi,Peter Rudnai,Neonilia Szeszenia-Dabrowska,David Zaridze,Ariana Znaor,Mark Lathrop,Mark Lathrop,Paul Brennan,Stefania Bandinelli,Timothy M. Frayling,Jack M. Guralnik,Yuri Milaneschi,John R. B. Perry,David Altshuler,David Altshuler,Roberto Elosua,S. Kathiresan,S. Kathiresan,Gavin Lucas,Olle Melander,Christopher J. O'Donnell,Stephen M. Schwartz,Benjamin F. Voight,Benjamin F. Voight,Johannes H. Smit,Johannes H. Smit,Eco J. C. de Geus,Stephen J. Chanock,Stephen J. Chanock,Fangyi Gu,Fangyi Gu,Susan E. Hankinson,David J. Hunter,David J. Hunter,Daniel I. Chasman,Brendan M. Everett,Brendan M. Everett,Brendan M. Everett,Guillaume Paré,Guillaume Paré,Paul M. Ridker,Ming D. Li,Hermine H. Maes,Janet Audrain-McGovern,Danielle Posthuma,Laura M. Thornton,Caryn Lerman,Jed E. Rose,John P. A. Ioannidis,John P. A. Ioannidis,Peter Kraft,Danyu Lin,Danyu Lin,Jason S. Liu,Federica Tozzi,Dawn M. Waterworth,Sreekumar G. Pillai,Pierandrea Muglia,Lefkos T. Middleton,Wade H. Berrettini,Christopher W. Knouff,Xin Yuan,Gérard Waeber,Peter Vollenweider,Martin Preisig,Nicholas J. Wareham,Jing Hua Zhao,Ruth J. F. Loos,Inês Barroso,Kay-Tee Khaw,Scott M. Grundy,Philip J. Barter,Robert W. Mahley,Antero Kesäniemi,Ruth McPherson,Ruth McPherson,John B. Vincent,John Strauss,James L. Kennedy,Anne Farmer,Peter McGuffin,Richard O. Day,Keith Matthews,Per Bakke,Amund Gulsvik,Susanne Lucae,Marcus Ising,T. Brueckl,S. Horstmann,Joachim Heinrich,Claudia Lamina,Claudia Lamina,Ozren Polasek,Lina Zgaga,Jennifer E. Huffman,Susan Campbell,Jaspal S. Kooner,John C. Chambers,Mary Susan Burnett,Joe Devaney,Augusto D. Pichard,Kenneth M. Kent,Lowell F. Satler,Joseph M. Lindsay,Ron Waksman,Stephen E. Epstein,James F. Wilson,Sarah H. Wild,Harry Campbell,Veronique Vitart,Muredach P. Reilly,Mingyao Li,Liming Qu,Robert L. Wilensky,William H. Matthai,Hakon Hakonarson,Daniel J. Rader,Andre Franke,Michael Wittig,Arne Schäfer,Manuela Uda,Antonio Terracciano,Xiangjun Xiao,Fabio Busonero,Paul Scheet,David Schlessinger,David St Clair,Dan Rujescu,Gonçalo R. Abecasis,Hans J. Grabe,Alexander Teumer,Henry Völzke,Astrid Petersmann,Ulrich John,Igor Rudan,Caroline Hayward,Alan F. Wright,Ivana Kolcic,Benjamin J. Wright,Anthony J. Balmforth,Carl A. Anderson,Tariq Ahmed,Christopher G. Mathew,Miles Parkes,Jack Satsangi,Mark J. Caulfield,Patricia B. Munroe,Martin Farrall,Anna F. Dominiczak,Jane Worthington,Wendy Thomson,Steve Eyre,Anne Barton,Vincent Mooser,Clyde Francks +316 more
TL;DR: The results strongly point to a common biological basis of the regulation of theregulation of the authors' appetite for tobacco and food, and thus the vulnerability to nicotine addiction and obesity, and the effect of single-nucleotide polymorphisms affecting body mass index (BMI).
Journal ArticleDOI
A look at linkage disequilibrium.
TL;DR: New data indicate that the extent of disequilibrium is highly variable across the genome, and that differences in disequ equilibrium levels between isolated and mixed populations are modest.