M
Michael Boehnke
Researcher at University of Michigan
Publications - 540
Citations - 155551
Michael Boehnke is an academic researcher from University of Michigan. The author has contributed to research in topics: Genome-wide association study & Type 2 diabetes. The author has an hindex of 152, co-authored 511 publications receiving 136681 citations. Previous affiliations of Michael Boehnke include SUNY Downstate Medical Center & Norwegian University of Science and Technology.
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Journal ArticleDOI
Sequencing and Imputation in GWAS: Cost-effective Strategies to Increase Power and Genomic Coverage Across Diverse Populations
Corbin Quick,Pramod Anugu,Solomon K. Musani,Scott T. Weiss,Scott T. Weiss,Scott T. Weiss,Esteban G. Burchard,Marquitta J. White,Kevin L. Keys,Francesco Cucca,Carlo Sidore,Michael Boehnke,Christian Fuchsberger,Christian Fuchsberger,Christian Fuchsberger +14 more
TL;DR: For poorly represented populations, sequencing a subset of participants is often most cost-effective, and can substantially increase imputation quality and GWAS power, and for populations that are well‐represented in existing reference panels, array genotyping alone is cost‐effective and well‐powered to detect common‐ and rare‐variant associations.
Journal ArticleDOI
Ordered subset analysis supports a glaucoma locus at GLC1I on chromosome 15 in families with earlier adult age at diagnosis
Abigail Woodroffe,Charles M. Krafchak,Nobuo Fuse,Nobuo Fuse,Paul R. Lichter,Sayoko E. Moroi,Robert M Schertzer,Robert M Schertzer,Catherine A. Downs,William L. Duren,Michael Boehnke,Julia E. Richards +11 more
TL;DR: Ordered subset analysis of this sample has provided evidence of linkage close to the previously identified GLC1I glaucoma locus on 15q11-13 in families with middle-aged mean age at diagnosis.
Journal ArticleDOI
Evaluation of genome-wide association study results through development of ontology fingerprints
TL;DR: It is demonstrated that ontology fingerprints can be used effectively to prioritize genes from GWA studies for experimental validation and identified genes relevant to lipid metabolism from the literature even in cases where such knowledge was not reflected in current annotation of these genes.
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney
Louise V. Wain,Ahmad Vaez,Rick Jansen,Roby Joehanes,Peter J. van der Most,A. Mesut Erzurumluoglu,Paul F. O'Reilly,Claudia P. Cabrera,Helen R. Warren,Lynda M. Rose,Germaine C. Verwoert,Jouke-Jan Hottenga,Rona J. Strawbridge,Tõnu Esko,Dan E. Arking,Shih-Jen Hwang,Xiuqing Guo,Zoltán Kutalik,Stella Trompet,Nick Shrine,Alexander Teumer,Janina S. Ried,Joshua C. Bis,Albert V. Smith,Najaf Amin,Ilja M. Nolte,Leo-Pekka Lyytikäinen,Anubha Mahajan,Nicholas J. Wareham,Edith Hofer,Peter K. Joshi,Kati Kristiansson,Michela Traglia,Aki S. Havulinna,Anuj Goel,Mike A. Nalls,Siim Sõber,Dragana Vuckovic,Jian'an Luan,Fabiola Del Greco M,Kristin L. Ayers,Jaume Marrugat,Daniela Ruggiero,Lorna M. Lopez,Teemu J. Niiranen,Stefan Enroth,Anne U. Jackson,Christopher P. Nelson,Jennifer E. Huffman,Weihua Zhang,Jonathan Marten,Ilaria Gandin,Sarah E. Harris,Tatijana Zemunik,Yingchang Lu,Evangelos Evangelou,Nabi Shah,Martin H. de Borst,Massimo Mangino,Bram P. Prins,Archie Campbell,Ruifang Li-Gao,Ganesh Chauhan,Christopher Oldmeadow,Gonçalo R. Abecasis,Maryam Abedi,Caterina Barbieri,Michael R. Barnes,Chiara Batini,John Beilby,Tineka Blake,Michael Boehnke,Erwin P. Bottinger,Peter S. Braund,Morris Brown,Marco Brumat,Harry Campbell,John C. Chambers,Massimiliano Cocca,Francis S. Collins,John M. C. Connell,Heather J. Cordell,Jeffrey Damman,Gail Davies,Eco J. C. de Geus,Renée de Mutsert,Joris Deelen,Yusuf Demirkale,Alex S. F. Doney,Marcus Dörr,Martin Farrall,Teresa Ferreira,Mattias Frånberg,He Gao,Vilmantas Giedraitis,Christian Gieger,Franco Giulianini,Alan J. Gow,Anders Hamsten,Tamara B. Harris,Albert Hofman,Elizabeth G. Holliday,Jennie Hui,Marjo-Riitta Järvelin,Åsa Johansson,Andrew D. Johnson,Pekka Jousilahti,Antti Jula,Mika Kähönen,Sekar Kathiresan,Kay-Tee Khaw,Ivana Kolcic,Seppo Koskinen,Claudia Langenberg,Marty Larson,Lenore J. Launer,Benjamin Lehne,David C. Liewald,Li Lin,Lars Lind,François Mach,Chrysovalanto Mamasoula,Cristina Menni,Borbala Mifsud,Yuri Milaneschi,Anna Morgan,Andrew D. Morris,Alanna C. Morrison,Peter J. Munson,Priyanka Nandakumar,Quang Tri Nguyen,Teresa Nutile,Albertine J. Oldehinkel,Ben A. Oostra,Elin Org,Sandosh Padmanabhan,Aarno Palotie,Guillaume Paré,Alison Pattie,Brenda W.J.H. Penninx,Neil Poulter,Peter P. Pramstaller,Olli T. Raitakari,Meixia Ren,Kenneth Rice,Paul M. Ridker,Harriëtte Riese,Samuli Ripatti,Antonietta Robino,Jerome I. Rotter,Igor Rudan,Yasaman Saba,Aude Saint Pierre,Cinzia Sala,Antti-Pekka Sarin,Reinhold Schmidt,Rodney J. Scott,Marc A. Seelen,Denis C. Shields,David S. Siscovick,Rossella Sorice,Alice Stanton,David J. Stott,Johan Sundström,Morris A. Swertz,Kent D. Taylor,Simon Thom,Ioanna Tzoulaki,Christophe Tzourio,André G. Uitterlinden,Uwe Völker,Peter Vollenweider,Sarah H. Wild,Gonneke Willemsen,Alan F. Wright,Jie Yao,Sébastien Thériault,David Conen,John Attia,Peter S. Sever,Stéphanie Debette,Dennis O. Mook-Kanamori,Eleftheria Zeggini,Tim D. Spector,Pim van der Harst,Colin N. A. Palmer,Anne-Claire Vergnaud,Ruth J. F. Loos,Ozren Polasek,John M. Starr,Giorgia Girotto,Caroline Hayward,Jaspal S. Kooner,C M Lindgren,Veronique Vitart,Nilesh J. Samani,Jaakko Tuomilehto,Ulf Gyllensten,Paul Knekt,Ian J. Deary,Marina Ciullo,Roberto Elosua,Bernard Keavney,Andrew A. Hicks,Robert A. Scott,Paolo Gasparini,Maris Laan,Yongmei Liu,Hugh Watkins,Catharina A. Hartman,Veikko Salomaa,Daniela Toniolo,Markus Perola,James F. Wilson,Helena Schmidt,Jing Hua Zhao,Terho Lehtimäki,Cornelia M. van Duijn,Vilmundur Gudnason,Bruce M. Psaty,Annette Peters,Rainer Rettig,Alan James,J. Wouter Jukema,David P. Strachan,Walter Palmas,Andres Metspalu,Erik Ingelsson,Dorret I. Boomsma,Oscar H. Franco,Murielle Bochud,Christopher Newton-Cheh,Patricia B. Munroe,Paul Elliott,Daniel I. Chasman,Aravinda Chakravarti,Joanne Knight,Andrew P. Morris,Daniel Levy,Martin D. Tobin,Harold Snieder,Mark J. Caulfield,Georg Ehret,T. Y. Alistair,J. P. Betholdson,Limin Xiao +245 more
Posted ContentDOI
Global Biobank Meta-analysis Initiative: powering genetic discovery across human diseases
Wei Zhou,Wei Zhou,Masahiro Kanai,Kuan-Han H. Wu,Rasheed Humaira,Rasheed Humaira,Rasheed Humaira,Kristin Tsuo,Kristin Tsuo,Jibril B Hirbo,Ying Wang,Ying Wang,Arjun Bhattacharya,Huiling Zhao,Shinichi Namba,Ida Surakka,Brooke N. Wolford,Valeria Lo Faro,Valeria Lo Faro,Valeria Lo Faro,Esteban A Lopera-Maya,Kristi Läll,Marie-Julie Favé,Sinéad B. Chapman,Juha Karjalainen,Mitja I. Kurki,Maasha Mutaamba,Ben Michael Brumpton,Sameer Chavan,Tzu-Ting Chen,Michelle Daya,Yi Ding,Yi Ding,Yen-Chen Anne Feng,Christopher R. Gignoux,Sarah E. Graham,Whitney E. Hornsby,Nathan Ingold,Ruth E. Johnson,Ruth E. Johnson,Triin Laisk,Kuang Lin,Jun Lv,Iona Y Millwood,Priit Palta,Priit Palta,Anita Pandit,Michael Preuss,Unnur Thorsteinsdottir,Jasmina Uzunovic,Matthew Zawistowski,Xue Zhong,Archie Campbell,Kristy Crooks,Geertruida H. de Bock,Nicholas J. Douville,Sarah Finer,Lars G. Fritsche,Chris Griffiths,Yu Guo,Karen A. Hunt,Takahiro Konuma,Takahiro Konuma,Riccardo E. Marioni,Jansonius Nomdo,Snehal Patil,Nicholas M. Rafaels,Anne Richmond,Jonathan A. Shortt,Peter Straub,Ran Tao,Brett Vanderwerff,Kathleen C. Barnes,Marike Boezen,Zhengming Chen,Chia-Yen Chen,Judy H. Cho,George Davey Smith,Hilary K. Finucane,Hilary K. Finucane,Lude Franke,Eric R. Gamazon,Eric R. Gamazon,Andrea Ganna,Andrea Ganna,Andrea Ganna,Tom R. Gaunt,Tian Ge,Hailiang Huang,Hailiang Huang,Jennifer E. Huffman,Clara Lajonchere,Matthew Law,Liming Li,Cecilia M. Lindgren,Ruth J. F. Loos,Stuart MacGregor,Koichi Matsuda,Catherine M. Olsen,David J. Porteous,Jordan A. Shavit,Harold Snieder,Richard C. Trembath,Judith M. Vonk,David C. Whiteman,Stephen J. Wicks,Cisca Wijmenga,John Wright,Jie Zheng,Xiang Zhou,Philip Awadalla,Philip Awadalla,Michael Boehnke,Nancy J. Cox,Daniel H. Geschwind,Caroline Hayward,Kristian Hveem,Eimear E. Kenny,Yen-Feng Lin,Yen-Feng Lin,Reedik Mägi,Hilary C. Martin,Sarah E. Medland,Yukinori Okada,Aarno Palotie,Aarno Palotie,Aarno Palotie,Bogdan Pasaniuc,Serena Sanna,Serena Sanna,Jordan W. Smoller,Kari Stefansson,David A. van Heel,Robin G. Walters,Sebastian Zoellner,BioMe,BioVU,Estonian Biobank,FinnGen,Generation Scotland,LifeLines,Mass General Brigham Biobank,Michigan Genomics Initiative,Qimr Berghofer Biobank,Taiwan Biobank,UK Biobank,Alicia R. Martin,Alicia R. Martin,Cristen J. Willer,Mark J. Daly,Benjamin M. Neale,Benjamin M. Neale +151 more
TL;DR: The Global Biobank Meta-analysis Initiative (GBMI) as mentioned in this paper is a collaborative network of 19 biobanks from 4 continents representing more than 2.1 million consented individuals with genetic data linked to electronic health records.